Search Results - "Bettuzzi, S."

Roles of Autophagy Induced by Natural Compounds in Prostate Cancer by Rizzi, Federica, Bettuzzi, Saverio, Modernelli, A., Naponelli, V.

“…Autophagy is a homeostatic mechanism through which intracellular organelles and proteins are degraded and recycled in response to increased metabolic demand or…”
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Molecular targets of (-)-epigallocatechin-3-gallate (EGCG): specificity and interaction with membrane lipid rafts by Patra, S K, Rizzi, F, Silva, A, Rugina, D O, Bettuzzi, S

“…Proteomic studies on anticancer activity of Green Tea Catechins (specifically EGCG) are suggesting a large set of protein targets that may directly interact…”
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Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation by Patra, S. K, Bettuzzi, S

“…DNA (cytosine-5-carbon) methylation is one of the hallmarks of mammalian chromatin modifications. Distinct methylation pattern can generate synergistic or…”
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Targeting Clusterin in prostate cancer by Rizzi, F, Bettuzzi, S

“…The biological function of Clusterin has been puzzling researchers for a long time since its first discovery and characterization in the early 80's. CLU plays…”
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Genetic inactivation of ApoJ clusterin: effects on prostate tumourigenesis and metastatic spread by Bettuzzi, S, Davalli, P, Davoli, S, Chayka, O, Rizzi, F, Belloni, L, Pellacani, D, Fregni, G, Astancolle, S, Fassan, M, Corti, A, Baffa, R, Sala, A

“…ApoJ/Clusterin (CLU) is a heterodimeric protein localized in the nucleus, cytoplasm or secretory organelles and involved in cell survival and neoplastic…”
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Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosis by Scaltriti, M, Bettuzzi, S, Sharrard, R M, Caporali, A, Caccamo, A E, Maitland, N J

“…Expression of the castration-induced clusterin protein is incompatible with the survival of human prostate cancer cells in tissues and in cell culture. To…”
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Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in patients with benign prostate hyperplasia by CRESCIOLI, C, FERRUZZI, P, COLLIE, E, ADORINI, L, MAGGI, M, CAPORALI, A, SCALTRITI, M, BETTUZZI, S, MANCINA, R, GELMINI, S, SERIO, M, VILLARI, D, VANNELLI, G. B

“…Calcitriol analogues might represent an interesting new therapy for benign prostate hyperplasia (BPH). We here report the preclinical characterization of…”
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Coordinate changes of polyamine metabolism regulatory proteins during the cell cycle of normal human dermal fibroblasts by Bettuzzi, S., Davalli, P., Astancolle, S., Pinna, C., Roncaglia, R., Boraldi, F., Tiozzo, R., Sharrard, M., Corti, A.

“…In human dermal fibroblasts, brought to quiescence (G 0) by serum starvation, the S phase peaked 24 h and G 2/M phases 36 h after serum re-addition. Under the…”
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Nuclear Translocation of a Clusterin Isoform Is Associated with Induction of Anoikis in SV40-Immortalized Human Prostate Epithelial Cells by CACCAMO, A E., SCALTRITI, M, CAPORALI, A, D'ARCA, D, SCORCIONI, F, CANDIANO, G, MANGIOLA, M, BETTUZZI, S

“…: Clusterin gene expression is potently induced in experimental models in which apoptosis is activated, such as rat prostate involution following castration…”
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Inhibition of Spontaneous and Androgen-Induced Prostate Growth by a Nonhypercalcemic Calcitriol Analog by Crescioli, C, Ferruzzi, P, Caporali, A, Mancina, R, Comerci, A, Muratori, M, Scaltriti, M, Vannelli, G. B, Smiroldo, S, Mariani, R, Villari, D, Bettuzzi, S, Serio, M, Adorini, L, Maggi, M

“…We have recently found that analog V (BXL-353, a calcitriol analog) inhibits growth factor (GF)-stimulated human benign prostate hyperplasia (BPH) cell…”
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Clinical relevance of the inhibitory effect of green tea catechins (GtCs) on prostate cancer progression in combination with molecular profiling of catechin-resistant tumors: an integrated view by Bettuzzi, S, Rizzi, F, Belloni, L

“…Prostate cancer (CaP) is a fast-growing health and social problem already representing the second leading cause of cancer-related death among men in Western…”
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Manipulation of the expression of regulatory genes of polyamine metabolism results in specific alterations of the cell-cycle progression by Scorcioni, F, Corti, A, Davalli, P, Astancolle, S, Bettuzzi, S

“…We have previously reported that cyclical phases of accumulation and depletion of polyamines occur during cell-cycle progression. Regulatory ornithine…”
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Increased levels of clusterin (SGP-2) mRNA and protein accompany rat ventral prostate involution following finasteride treatment by Astancolle, S, Guidetti, G, Pinna, C, Corti, A, Bettuzzi, S

“…Finasteride is a well-known inhibitor of the prostatic enzyme 5 alpha-reductase type 2 which prevents conversion of testosterone into 5…”
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Effet hépatoprotecteur et antiradicalaire d’un extrait butanolique de Rhantherium suaveolens by Amrani, A., Benaissa, O., Boubekri, N., Zama, D., Biod, K., Beroal, N., Benayache, F., Benayache, S., Bettuzzi, S.

“…Résumé Les effets hépatoprotecteur et antioxydant d’un extrait butanolique de Rhantherium suaveolens et de la vitamine E sont étudiés sur un modèle…”
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Differential induction of spermidine/spermine N 1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N 1,N 12-bis(ethyl)spermine involves transcriptional and post-transcriptional regulation by Marverti, G., Bettuzzi, S., Astancolle, S., Pinna, C., Monti, M.G., Moruzzi, M.S.

“…The growth inhibition that occurs in cisplatin-sensitive 2008 human ovarian cancer cells in response to the spermine analogue, N 1,N 12-bis(ethyl)spermine…”
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Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis by Bettuzzi, S, Hiipakka, R A, Gilna, P, Liao, S T

“…The concentrations of a small number of mRNAs in the rat ventral prostate increase after castration and then decrease upon androgen treatment. Since the…”
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Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia : A preliminary report from a one-year proof-of-principle study by BETTUZZI, Saverio, BRAUSI, Maurizio, RIZZI, Federica, CASTAGNETTI, Giovanni, PERACCHIA, Giancarlo, CORTI, Arnaldo

“…Green tea catechins (GTCs) proved to be effective in inhibiting cancer growth in several experimental models. Recent studies showed that 30% of men with…”
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Clusterin (SGP-2) gene expression is cell cycle dependent in normal human dermal fibroblasts by Bettuzzi, S, Astancolle, S, Guidetti, G, Moretti, M, Tiozzo, R, Corti, A

“…In confluent human dermal fibroblasts brought to quiescence (G 0) by serum starvation, the S phase peaked at 24 h after serum re-addiction and G 2/M phase…”
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Differential induction of spermidine/spermine N1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N1, N12-bis(ethyl)spermine involves transcriptional and post-transcriptional regulation by MARVERTI, G, BETTUZZI, S, ASTANCOLLE, S, PINNA, C, MONTI, M. G, MORUZZI, M. S

“…The growth inhibition that occurs in cisplatin-sensitive 2008 human ovarian cancer cells in response to the spermine analogue, N1,N12-bis(ethyl)spermine…”
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Different localization of spermidine/spermine N 1 -acetyltransferase and ornithine decarboxylase transcripts in the rat kidney by Bettuzzi, S., Marinelli, M., Strocchi, P., Davalli, P., Cevolani, D., Corti, A.

“…In situ hybridization histochemistry of transverse sections from male rat kidney showed that the mRNA of the regulatory enzyme of polyamine degradation,…”
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