Search Results - "Betters, Ryan K"

Thioflavin S Staining and Amyloid Formation Are Unique to Mixed Tauopathies by Fiock, Kimberly L., Betters, Ryan K., Hefti, Marco M.

“…Tau phosphorylation, aggregation, and toxicity are the main drivers of neurodegeneration in multiple tauopathies, including Alzheimer’s disease (AD) and…”
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Tau Phosphorylation and Aggregation in the Developing Human Brain by Hefti, Marco M, Kim, SoongHo, Bell, Aaron J, Betters, Ryan K, Fiock, Kimberly L, Iida, Megan A, Smalley, Martin E, Farrell, Kurt, Fowkes, Mary E, Crary, John F

“…Abstract Tau hyperphosphorylation, mostly at serine (Ser) or threonine (Thr) residues, plays a key role in the pathogenesis of Alzheimer disease (AD) and other…”
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Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins by Betters, Ryan K, Luhmann, Emma, Gottschalk, Amy C, Xu, Zhen, Shin, Mallory R, Ptak, Christopher P, Fiock, Kimberly L, Radoshevich, Lilliana C, Hefti, Marco M

“…Despite exhibiting tau phosphorylation similar to Alzheimer's disease (AD), the human fetal brain is remarkably resilient to tau aggregation and toxicity. To…”
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