Search Results - "Betters, Jenna"

Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport by Jia, Lin, Betters, Jenna L, Yu, Liqing

“…Increased blood cholesterol is an independent risk factor for atherosclerotic cardiovascular disease. Cholesterol homeostasis in the body is controlled mainly…”
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NPC1L1 and cholesterol transport by Betters, Jenna L., Yu, Liqing

“…The polytopic transmembrane protein, Niemann–Pick C1-Like 1 (NPC1L1), is enriched in the apical membrane of small intestine absorptive enterocytes where it…”
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The Serine Hydrolase ABHD6 Is a Critical Regulator of the Metabolic Syndrome by Thomas, Gwynneth, Betters, Jenna L., Lord, Caleb C., Brown, Amanda L., Marshall, Stephanie, Ferguson, Daniel, Sawyer, Janet, Davis, Matthew A., Melchior, John T., Blume, Lawrence C., Howlett, Allyn C., Ivanova, Pavlina T., Milne, Stephen B., Myers, David S., Mrak, Irina, Leber, Vera, Heier, Christoph, Taschler, Ulrike, Blankman, Jacqueline L., Cravatt, Benjamin F., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Zimmermann, Robert, Brown, H. Alex, Brown, J. Mark

“…The serine hydrolase α/β hydrolase domain 6 (ABHD6) has recently been implicated as a key lipase for the endocannabinoid 2-arachidonylglycerol (2-AG) in the…”
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CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance[S] by Brown, J. Mark, Betters, Jenna L., Lord, Caleb, Ma, Yinyan, Han, Xianlin, Yang, Kui, Alger, Heather M., Melchior, John, Sawyer, Janet, Shah, Ramesh, Wilson, Martha D., Liu, Xiuli, Graham, Mark J., Lee, Richard, Crooke, Rosanne, Shulman, Gerald I., Xue, Bingzhong, Shi, Hang, Yu, Liqing

“…Mutations of Comparative Gene Identification-58 (CGI-58) in humans cause triglyceride (TG) accumulation in multiple tissues. Mice genetically lacking CGI-58…”
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Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice by Guo, Feng, Ma, Yinyan, Kadegowda, Anil K.G., Betters, Jenna L., Xie, Ping, Liu, George, Liu, Xiuli, Miao, Hongming, Ou, Juanjuan, Su, Xiong, Zheng, Zhenlin, Xue, Bingzhong, Shi, Hang, Yu, Liqing

“…Triglyceride (TG) accumulation in hepatocytes (hepatic steatosis) preludes the development of advanced nonalcoholic fatty liver diseases (NAFLDs) such as…”
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Nitric oxide increases GLUT4 expression and regulates AMPK signaling in skeletal muscle by Lira, Vitor A, Soltow, Quinlyn A, Long, Jodi H D, Betters, Jenna L, Sellman, Jeff E, Criswell, David S

“…Nitric oxide (NO) and 5'-AMP-activated protein kinase (AMPK) are involved in glucose transport and mitochondrial biogenesis in skeletal muscle. Here, we…”
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Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis[S] by Jia, Lin, Ma, Yinyan, Rong, Shunxing, Betters, Jenna L., Xie, Ping, Chung, Soonkyu, Wang, Nanping, Tang, Weiqing, Yu, Liqing

“…Niemann-Pick C1-Like 1 (NPC1L1) mediates intestinal absorption of dietary and biliary cholesterol. Ezetimibe, by inhibiting NPC1L1 function, is widely used to…”
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Trolox Attenuates Mechanical Ventilation-induced Diaphragmatic Dysfunction and Proteolysis by Betters, Jenna L, Criswell, David S, Shanely, R. Andrew, Van Gammeren, Darin, Falk, Darin, DeRuisseau, Keith C, Deering, Melissa, Yimlamai, Tossaporn, Powers, Scott K

“…Prolonged mechanical ventilation results in diaphragmatic oxidative injury, elevated proteolysis, fiber atrophy, and reduced force-generating capacity. We…”
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Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation by Lord, Caleb C., Ferguson, Daniel, Thomas, Gwynneth, Brown, Amanda L., Schugar, Rebecca C., Burrows, Amy, Gromovsky, Anthony D., Betters, Jenna, Neumann, Chase, Sacks, Jessica, Marshall, Stephanie, Watts, Russell, Schweiger, Martina, Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Lathia, Justin D., Sakaguchi, Takuya F., Lehner, Richard, Haemmerle, Guenter, Zechner, Rudolf, Brown, J. Mark

“…Adipose triglyceride lipase (ATGL) and comparative gene identification 58 (CGI-58) are critical regulators of triacylglycerol (TAG) turnover. CGI-58 is thought…”
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CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action by LORD, Caleb C, BETTERS, Jenna L, LEE, Richard G, CROOKE, Rosanne M, GRAHAM, Mark J, PARKS, John S, BRASAEMLE, Dawn L, FESSLER, Michael B, BROWN, H. Alex, BROWN, J. Mark, IVANOVA, Pavlina T, MILNE, Stephen B, MYERS, David S, MADENSPACHER, Jennifer, THOMAS, Gwynneth, CHUNG, Soonkyu, MINGXIA LIU, DAVIS, Matthew A

“…Mutations of comparative gene identification 58 (CGI-58) in humans cause Chanarin-Dorfman syndrome, a rare autosomal recessive disease in which excess…”
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Adipose-selective overexpression of ABHD5/CGI-58 does not increase lipolysis or protect against diet-induced obesity by Caviglia, Jorge M., Betters, Jenna L., Dapito, Dianne-Helerie, Lord, Caleb C., Sullivan, Sean, Chua, Streamson, Yin, Terry, Sekowski, Anna, Mu, Haiyan, Shapiro, Lawrence, Brown, J. Mark, Brasaemle, Dawn L.

“…Adipose triglyceride lipase (ATGL) catalyzes the first step of triacylglycerol hydrolysis in adipocytes. Abhydrolase domain 5 (ABHD5) increases ATGL activity…”
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In vivo inhibition of nitric oxide synthase impairs upregulation of contractile protein mRNA in overloaded plantaris muscle by Sellman, Jeff E, DeRuisseau, Keith C, Betters, Jenna L, Lira, Vitor A, Soltow, Quinlyn A, Selsby, Joshua T, Criswell, David S

“…Center for Exercise Science, University of Florida, Gainesville, Florida Submitted 1 August 2005 ; accepted in final form 14 September 2005 Inhibition of…”
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Supplemental nitric oxide augments satellite cell activity on cultured myofibers from aged mice by Betters, Jenna L., Lira, Vitor A., Soltow, Quinlyn A., Drenning, Jason A., Criswell, David S.

“…Skeletal muscle regenerative potential is reduced with aging. We hypothesized that in vitro activation of muscle satellite cells would be compromised, and that…”
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Nitric oxide regulates stretch-induced proliferation in C2C12 myoblasts by Soltow, Quinlyn A, Lira, Vitor A, Betters, Jenna L, Long, Jodi H. D, Sellman, Jeff E, Zeanah, Elizabeth H, Criswell, David S

“…Mechanical stretch of skeletal muscle activates nitric oxide (NO) production and is an important stimulator of satellite cell proliferation. Further,…”
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Arginine supplementation induces myoblast fusion via augmentation of nitric oxide production by Long, Jodi H D, Lira, Vitor A, Soltow, Quinlyn A, Betters, Jenna L, Sellman, Jeff E, Criswell, David S

“…The semi-essential amino acid, L-arginine (L-Arg), is the substrate for endogenous synthesis of nitric oxide, a molecule that is involved in myoblast…”
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Ibuprofen inhibits skeletal muscle hypertrophy in rats by SOLTOW, Quinlyn A, BETTERS, Jenna L, SELLMAN, Jeff E, LIRA, Vitor A, LONG, Jodi H. D, CRISWELL, David S

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Cumulative effects of aging and mechanical ventilation on in vitro diaphragm function by Criswell, David S, Shanely, R Andrew, Betters, Jenna J, McKenzie, Michael J, Sellman, Jeff E, Van Gammeren, Darin L, Powers, Scott K

“…Unloading the diaphragm, via mechanical ventilation (MV), results in significant diaphragmatic atrophy, contractile dysfunction, and oxidative stress in young…”
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Nitric oxide reverses prednisolone-induced inactivation of muscle satellite cells by Betters, Jenna L., Long, Jodi H.D., Howe, Kathleen S., Braith, Randy W., Soltow, Quinlyn A., Lira, Vitor A., Criswell, David S.

“…Long‐term corticosteroid therapy causes myopathy and can inhibit regeneration of skeletal muscle. Therefore, we hypothesized that corticosteroid exposure…”
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Abstract 109: Role of ApoAIV in ApoB Lipoprotein Assembly and Triglyceride Transport by Fabritius, Melissa A, MacArthur, Philip S, Betters, Jenna L, Brown, J Mark, Shelness, Gregory S

“…Abstract only Apolipoprotein A-IV (apoAIV) is a lipid binding protein expressed primarily in mammalian intestine and also in rodent liver. While in vitro…”
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Regulation of the alpha beta hydrolase domain (ABHD) protein family in murine and human obesity by Brown, J. Mark, Martinez, Kristina, Betters, Jenna, Shores, Nathan, Rudel, Lawrence L, McIntosh, Michael K, Thomas, Gwynneth

“…Abstract only In the search for factors that regulate obesity and diabetes, we have discovered a novel lipid‐signaling pathway involving the enzyme alpha beta…”
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