Search Results - "Bettecken, T"

TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies by Erhardt, A, Czibere, L, Roeske, D, Lucae, S, Unschuld, P G, Ripke, S, Specht, M, Kohli, M A, Kloiber, S, Ising, M, Heck, A, Pfister, H, Zimmermann, P, Lieb, R, Pütz, B, Uhr, M, Weber, P, Deussing, J M, Gonik, M, Bunck, M, Keßler, M S, Frank, E, Hohoff, C, Domschke, K, Krakowitzky, P, Maier, W, Bandelow, B, Jacob, C, Deckert, J, Schreiber, S, Strohmaier, J, Nöthen, M, Cichon, S, Rietschel, M, Bettecken, T, Keck, M E, Landgraf, R, Müller-Myhsok, B, Holsboer, F, Binder, E B

“…The lifetime prevalence of panic disorder (PD) is up to 4% worldwide and there is substantial evidence that genetic factors contribute to the development of…”
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The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders by Thoeringer, C. K., Ripke, S., Unschuld, P. G., Lucae, S., Ising, M., Bettecken, T., Uhr, M., Keck, M. E., Mueller-Myhsok, B., Holsboer, F., Binder, E. B., Erhardt, A.

“…Recent evidence suggests that the GABA transporter 1 (GAT-1; SLC6A1) plays a role in the pathophysiology and treatment of anxiety disorders. In order to…”
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MS susceptibility is not affected by single nucleotide polymorphisms in the MMP9 gene by Nischwitz, S, Wolf, C, Andlauer, T.F.M, Czamara, D, Zettl, U.K, Rieckmann, P, Buck, D, Ising, M, Bettecken, T, Mueller-Myhsok, B, Weber, F

“…Abstract Matrix metalloproteinase 9 (MMP9) plays an important role in the pathogenesis of multiple sclerosis (MS). However, the impact of genetic variants…”
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IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations by Weber, F, Fontaine, B, Cournu-Rebeix, I, Kroner, A, Knop, M, Lutz, S, Müller-Sarnowski, F, Uhr, M, Bettecken, T, Kohli, M, Ripke, S, Ising, M, Rieckmann, P, Brassat, D, Semana, G, Babron, M-C, Mrejen, S, Gout, C, Lyon-Caen, O, Yaouanq, J, Edan, G, Clanet, M, Holsboer, F, Clerget-Darpoux, F, Müller-Myhsok, B

“…Multiple sclerosis (MS) is the most common chronic inflammatory neurologic disorder diagnosed in young adults and, due to its chronic course, is responsible…”
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Variants within the GABA transaminase (ABAT) gene region are associated with somatosensory evoked EEG potentials in families at high risk for affective disorders by Wegerer, M, Adena, S, Pfennig, A, Czamara, D, Sailer, U, Bettecken, T, Müller-Myhsok, B, Modell, S, Ising, M

“…Depression frequently co-occurs with somatization, and somatic complaints have been reported as a vulnerability marker for affective disorders observable…”
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Mitochondrial 12S rRNA susceptibility mutations in aminoglycoside-associated and idiopathic bilateral vestibulopathy by Elstner, M., Schmidt, C., Zingler, V.C., Prokisch, H., Bettecken, T., Elson, J.L., Rudolph, G., Bender, A., Halmagyi, G.M., Brandt, T., Strupp, M., Klopstock, T.

“…The mitochondrial 12S rRNA is considered a hotspot for mutations associated with nonsyndromic (NSHL) and aminoglycoside-induced hearing loss (AIHL). Although…”
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Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways by Ditzen, C, Varadarajulu, J, Czibere, L, Gonik, M, Targosz, B S, Hambsch, B, Bettecken, T, Keßler, M S, Frank, E, Bunck, M, Teplytska, L, Erhardt, A, Holsboer, F, Müller-Myhsok, B, Landgraf, R, Turck, C W

“…In our biomarker identification efforts, we have reported earlier on a protein that differs in its electrophoretic mobility between mouse lines bred either for…”
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More CLEC16A gene variants associated with multiple sclerosis by Nischwitz, S., Cepok, S., Kroner, A., Wolf, C., Knop, M., Müller-Sarnowski, F., Pfister, H., Rieckmann, P., Hemmer, B., Ising, M., Uhr, M., Bettecken, T., Holsboer, F., Müller-Myhsok, B., Weber, F.

“…Nischwitz S, Cepok S, Kroner A, Wolf C, Knop M, Müller‐Sarnowski F, Pfister H, Rieckmann P, Hemmer B, Ising M, Uhr M, Bettecken T, Holsboer F, Müller‐Myhsok B,…”
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Family-based association study of serotonergic candidate genes and attention-deficit/hyperactivity disorder in a German sample by Heiser, P, Dempfle, A, Friedel, S, Konrad, K, Hinney, A, Kiefl, H, Walitza, S, Bettecken, T, Saar, K, Linder, M, Warnke, A, Herpertz-Dahlmann, B, Schäfer, H, Remschmidt, H, Hebebrand, J

“…Alterations in the serotonergic pathway have been implicated in the pathogenesis of attention-deficit/hyperactivity disorder (ADHD). The aim of this study was…”
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Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism by Heck, A, Lieb, R, Unschuld, P G, Ellgas, A, Pfister, H, Lucae, S, Erhardt, A, Himmerich, H, Horstmann, S, Kloiber, S, Ripke, S, Müller-Myhsok, B, Bettecken, T, Uhr, M, Holsboer, F, Ising, M

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Sequence fossils, triplet expansion, and reconstruction of earliest codons by Trifonov, E.N., Bettecken, T.

“…mRNA sequences are known to carry a hidden periodical pattern (GCU) n, which may be considered a remnant of sequence organization of mRNA early in its…”
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No association of sequence variants in the neuropeptide Y2 receptor (NPY2R) gene with early onset obesity in Germans by Wang, H-J, Wermter, A-K, Nguyen, T T, Scherag, A, Reichwald, K, Waldenmaier, B, Lichtner, P, Bettecken, T, Hebebrand, J, Hinney, A

“…The neuropeptide Y2 receptor (NPY2R) has been implicated in body weight regulation both in humans and rodents. We investigated if genetic variation in the…”
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The molecular basis for Duchenne versus Becker muscular dystrophy: correlation of severity with type of deletion by KOENIG, M, BEGGS, A. H, DE LA CHAPELLE, A, KIURU, A, SAVONTAUS, M.-L, GILGENKRANTZ, H, RECAN, D, CHELLY, J, KAPLAN, J.-C, COVONE, A. E, ARCHIDIACONO, N, ROMEO, G, MOYER, M, SCHERPF, S, HEINDRICH, K, BETTECKEN, T, MENG, G, MÜLLER, C. R, LINDÖF, M, KAARIAINEN, H

“…About 60% of both Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) is due to deletions of the dystrophin gene. For cases with a deletion…”
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Tetrasomy 21pter→q21.2 in a male infant without typical Down’s syndrome dysmorphic features but moderate mental retardation by Rost, I, Fiegler, H, Fauth, C, Carr, P, Bettecken, T, Kraus, J, Meyer, C, Enders, A, Wirtz, A, Meitinger, T, Carter, N P, Speicher, M R

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On the origin of deletions and point mutations in Duchenne muscular dystrophy: most deletions arise in oogenesis and most point mutations result from events in spermatogenesis by Grimm, T, Meng, G, Liechti-Gallati, S, Bettecken, T, Müller, C R, Müller, B

“…We present the results of a study of the rate and origin of mutations in Duchenne muscular dystrophy (DMD). Depending on the type of mutation…”
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Consciousness disturbances in megalencephalic leukoencephalopathy with subcortical cysts by Bugiani, M, Moroni, I, Bizzi, A, Nardocci, N, Bettecken, T, Gärtner, J, Uziel, G

“…Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a genetic disorder featuring diffuse MRI white matter abnormalities and a discrepantly mild…”
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs by Lee, S Hong, Ripke, Stephan, Neale, Benjamin M, Faraone, Stephen V, Purcell, Shaun M, Perlis, Roy H, Mowry, Bryan J, Thapar, Anita, Goddard, Michael E, Witte, John S, Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A, Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E, Asherson, Philip, Azevedo, Maria H, Backlund, Lena, Badner, Judith A, Bailey, Anthony J, Banaschewski, Tobias, Barchas, Jack D, Barnes, Michael R, Barrett, Thomas B, Bass, Nicholas, Battaglia, Agatino, Bauer, Michael, Bayés, Mònica, Bellivier, Frank, Bergen, Sarah E, Berrettini, Wade, Betancur, Catalina, Bettecken, Thomas, Biederman, Joseph, Binder, Elisabeth B, Black, Donald W, Blackwood, Douglas H R, Bloss, Cinnamon S, Boehnke, Michael, Boomsma, Dorret I, Breen, Gerome, Breuer, René, Bruggeman, Richard, Cormican, Paul, Buccola, Nancy G, Buitelaar, Jan K, Bunney, William E, Buxbaum, Joseph D, Byerley, William F, Byrne, Enda M, Caesar, Sian, Cahn, Wiepke, Cantor, Rita M, Casas, Miguel, Chakravarti, Aravinda, Chambert, Kimberly, Choudhury, Khalid, Cichon, Sven, Cloninger, C Robert, Collier, David A, Cook, Edwin H, Coon, Hilary, Cormand, Bru, Corvin, Aiden, Coryell, William H, Craig, David W, Craig, Ian W, Crosbie, Jennifer, Cuccaro, Michael L, Curtis, David, Czamara, Darina, Datta, Susmita, Dawson, Geraldine, Day, Richard, De Geus, Eco J, Degenhardt, Franziska, Djurovic, Srdjan, Donohoe, Gary J, Doyle, Alysa E, Duan, Jubao, Dudbridge, Frank, Duketis, Eftichia, Ebstein, Richard P, Edenberg, Howard J, Elia, Josephine, Ennis, Sean, Etain, Bruno, Fanous, Ayman, Farmer, Anne E, Ferrier, I Nicol, Flickinger, Matthew, Fombonne, Eric, Foroud, Tatiana, Frank, Josef, Franke, Barbara, Fraser, Christine

“…Naomi Wray and colleagues report an analysis of genome-wide association data sets from the Psychiatric Genomics Consortium for five psychiatric disorders. They…”
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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways by O'Dushlaine, C., Rossin, L., Lee P., H., Duncan, L., Parikshak N., N., Newhouse, S., Ripke, S., Neale B., M., Purcell S., M., Posthuma, D., Nurnberger J., I., Lee S., H., Faraone S., V., Perlis R., H., Mowry B., J., Thapar, A., Goddard M., E., Witte J., S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen O., A., Anjorin, A., Anney, R., Anttila, V., Arking D., E., Asherson, P., Azevedo M., H., Backlund, L., Badner J., A., Bailey A., J., Banaschewski, T., Barchas J., D., Barnes M., R., Barrett T., B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen S., E., Berrettini, W., Betancur, Catalina, Bettecken, T., Biederman, J., Binder E., B., Black D., W., Blackwood D., H., Bloss C., S., Boehnke, M., Boomsma D., I., Breuer, R., Bruggeman, R., Cormican, P., Buccola N., G., Buitelaar J., K., Bunney W., E., Buxbaum J., D., Byerley W., F., Byrne E., M., Caesar, S., Cahn, W., Cantor R., M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Mattheisen, M., Cloninger C., R., Collier D., A., Cook E., H., Coon, H., Cormand, B., Corvin, A., Coryell W., H., Craig D., W., Craig I., W., Crosbie, J., Cuccaro M., L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., de Geus E., J., Degenhardt, F., Djurovic, S., Donohoe G., J., Doyle A., E., Duan, J., Dudbridge, F., Duketis, E., Ebstein R., P., Edenberg H., J., Elia, J., Ennis, S., Etain, B., Fanous, F.

“…Better analytical methods are needed to extract biological meaning from genome-wide association studies (GWAS) of psychiatric disorders. Here the authors take…”
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A mega-analysis of genome-wide association studies for major depressive disorder by Ripke, Stephan, Wray, Naomi R, Lewis, Cathryn M, Hamilton, Steven P, Weissman, Myrna M, Breen, Gerome, Byrne, Enda M, Blackwood, Douglas H R, Boomsma, Dorret I, Cichon, Sven, Heath, Andrew C, Holsboer, Florian, Lucae, Susanne, Madden, Pamela A F, Martin, Nicholas G, McGuffin, Peter, Muglia, Pierandrea, Noethen, Markus M, Penninx, Brenda P, Pergadia, Michele L, Potash, James B, Rietschel, Marcella, Lin, Danyu, Müller-Myhsok, Bertram, Shi, Jianxin, Steinberg, Stacy, Grabe, Hans J, Lichtenstein, Paul, Magnusson, Patrik, Perlis, Roy H, Preisig, Martin, Smoller, Jordan W, Stefansson, Kari, Uher, Rudolf, Kutalik, Zoltan, Tansey, Katherine E, Teumer, Alexander, Viktorin, Alexander, Barnes, Michael R, Bettecken, Thomas, Binder, Elisabeth B, Breuer, René, Castro, Victor M, Churchill, Susanne E, Coryell, William H, Craddock, Nick, Craig, Ian W, Czamara, Darina, De Geus, Eco J, Degenhardt, Franziska, Farmer, Anne E, Fava, Maurizio, Frank, Josef, Gainer, Vivian S, Gallagher, Patience J, Gordon, Scott D, Goryachev, Sergey, Gross, Magdalena, Guipponi, Michel, Henders, Anjali K, Herms, Stefan, Hickie, Ian B, Hoefels, Susanne, Hoogendijk, Witte, Hottenga, Jouke Jan, Iosifescu, Dan V, Ising, Marcus, Jones, Ian, Jones, Lisa, Jung-Ying, Tzeng, Knowles, James A, Kohane, Isaac S, Kohli, Martin A, Korszun, Ania, Landen, Mikael, Lawson, William B, Lewis, Glyn, Macintyre, Donald, Maier, Wolfgang, Mattheisen, Manuel, McGrath, Patrick J, McIntosh, Andrew, McLean, Alan, Middeldorp, Christel M, Middleton, Lefkos, Montgomery, Grant M, Murphy, Shawn N, Nauck, Matthias, Nolen, Willem A, Nyholt, Dale R, O'Donovan, Michael, Oskarsson, Högni, Pedersen, Nancy, Scheftner, William A, Schulz, Andrea, Schulze, Thomas G, Shyn, Stanley I, Sigurdsson, Engilbert, Slager, Susan L, Smit, Johannes H

“…Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have met with limited success. We sought to increase statistical power to…”
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Reduced amplification efficiency of KIAA0027/MLC1 alleles: implications for the molecular diagnosis of megalencephalic leukoencephalopathy with subcortical cysts by Bettecken, T., Rubie, C., Lichtner, P., Siekiera, M., Meitinger, T., Stöber, G.

“…Autosomal recessive megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare childhood-onset spongiform leukodystrophy with macrocephaly and…”
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