Search Results - "Betsou, Fay"

Fitness for purpose of stabilized stool samples for bile acid metabolite analyses by Neuberger-Castillo, Lorie, Ammerlaan, Wim, Betsou, Fay

“…Biobanks and cohort studies are increasingly utilizing chemical stabilizers to collect and store stool samples for downstream DNA-based microbiome analyses…”
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Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease by Nickels, Sarah Louise, Modamio, Jennifer, Mendes-Pinheiro, Bárbara, Monzel, Anna Sophia, Betsou, Fay, Schwamborn, Jens Christian

“…The study of human midbrain development and midbrain related diseases, like Parkinson’s disease (PD), is limited by deficiencies in the currently available and…”
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The DxConnect Virtual Biobank connects diagnostic researchers to clinical samples by Ongarello, Stefano, Fernández Suárez, Marta, Betsou, Fay

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Distinct metabolomic signature in cerebrospinal fluid in early parkinson's disease by Trezzi, Jean‐Pierre, Galozzi, Sara, Jaeger, Christian, Barkovits, Katalin, Brockmann, Kathrin, Maetzler, Walter, Berg, Daniela, Marcus, Katrin, Betsou, Fay, Hiller, Karsten, Mollenhauer, Brit

“…Objective: The purpose of this study was to profile cerebrospinal fluid (CSF) from early‐stage PD patients for disease‐related metabolic changes and to…”
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Preanalytical robustness of blood collection tubes with RNA stabilizers by Stellino, Chiara, Hamot, Gaël, Bellora, Camille, Trouet, Johanna, Betsou, Fay

“…Background Efficient blood stabilization is essential to obtaining reliable and comparable RNA analysis data in preclinical operations. PAXgene (Qiagen, Becton…”
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Introduction of BD Vacutainer ® Barricor™ tubes in clinical biobanking and application of amino acid and cytokine quality indicators to Barricor plasma by Knutti, Nadine, Neugebauer, Sophie, Scherr, Franziska, Mathay, Conny, Marchese, Monica, Henry, Estelle, Palm, Julia, Betsou, Fay, Kiehntopf, Michael

“…The use of BD Vacutainer Barricor™ tubes (BAR) can reduce turnaround time (TAT) and improve separation of plasma from cellular components using a specific…”
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Biospecimen Science of Blood for cfDNA Genetic Analyses by Ammerlaan, Wim, Betsou, Fay

“…Purpose of Review cfDNA is increasingly used for biomonitoring oncological diseases or pregnancy status by different genetic analyses. Uncontrolled…”
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Preanalytical challenges - time for solutions by Lippi, Giuseppe, Betsou, Fay, Cadamuro, Janne, Cornes, Michael, Fleischhacker, Michael, Fruekilde, Palle, Neumaier, Michael, Nybo, Mads, Padoan, Andrea, Plebani, Mario, Sciacovelli, Laura, Vermeersch, Pieter, von Meyer, Alexander, Simundic, Ana-Maria

“…The European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE) was originally established in…”
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Implementing routine monitoring for nuclease contamination of equipment and consumables into the quality Management system of a laboratory by Henry, Estelle, Charalambous, Eleftheria, Betsou, Fay, Mathieson, William

“…Nucleases are ubiquitous in the environment, present in biospecimens and widely used in many laboratory processes. However, in the wrong context, as…”
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Multicenter Evaluation of Circulating Plasma MicroRNA Extraction Technologies for the Development of Clinically Feasible Reverse Transcription Quantitative PCR and Next-Generation Sequencing Analytical Work Flows by Kloten, Vera, Neumann, Martin H D, Di Pasquale, Francesca, Sprenger-Haussels, Markus, Shaffer, Jonathan M, Schlumpberger, Martin, Herdean, Andrei, Betsou, Fay, Ammerlaan, Wim, Af Hällström, Taija, Serkkola, Elina, Forsman, Tarja, Lianidou, Evi, Sjöback, Robert, Kubista, Mikael, Bender, Sebastian, Lampignano, Rita, Krahn, Thomas, Schlange, Thomas

“…In human body fluids, microRNA (miRNA) can be found as circulating cell-free miRNA (cfmiRNA), as well as secreted into extracellular vesicles (EVmiRNA). miRNAs…”
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Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID by Neves, Rui P L, Ammerlaan, Wim, Andree, Kiki C, Bender, Sebastian, Cayrefourcq, Laure, Driemel, Christiane, Koch, Claudia, Luetke-Eversloh, Merlin Verena, Oulhen, Marianne, Rossi, Elisabetta, Alix-Panabières, Catherine, Betsou, Fay, Farace, Françoise, Riethdorf, Sabine, Schlange, Thomas, Wikman, Harriet, Zamarchi, Rita, Pantel, Klaus, Terstappen, Leon W M M, Stoecklein, Nikolas H

“…Abstract Background Multiple technologies are available for detection of circulating tumor cells (CTCs), but standards to evaluate their technical performance…”
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RNA and microRNA Stability in PAXgene-Fixed Paraffin-Embedded Tissue Blocks After Seven Years’ Storage by Sanchez, Ignacio, Betsou, Fay, Culot, Bénédicte, Frasquilho, Sonia, McKay, Siobhan C, Pericleous, Stephanos, Smith, Colleen, Thomas, Gerry, Mathieson, William

“…Abstract Objectives To evaluate the stability of RNA and microRNA (miRNA) in PAXgene-fixed paraffin-embedded tissue blocks after 7 years’ storage. Methods RNA…”
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Protocol for a prospective, longitudinal cohort of people with COVID-19 and their household members to study factors associated with disease severity: the Predi-COVID study by Fagherazzi, Guy, Fischer, Aurélie, Betsou, Fay, Vaillant, Michel, Ernens, Isabelle, Masi, Silvana, Mossong, Joel, Staub, Therese, Brault, Dominique, Bahlawane, Christelle, Rashid, Mohammed Ally, Ollert, Markus, Gantenbein, Manon, Huiart, Laetitia

“…IntroductionA few major clinical factors such as sex, obesity or comorbidities have already been associated with COVID-19 severity, but there is a need to…”
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Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females by Capelle, Christophe M., Ciré, Séverine, Hedin, Fanny, Hansen, Maxime, Pavelka, Lukas, Grzyb, Kamil, Kyriakis, Dimitrios, Hunewald, Oliver, Konstantinou, Maria, Revets, Dominique, Tslaf, Vera, Marques, Tainá M., Gomes, Clarissa P. C., Baron, Alexandre, Domingues, Olivia, Gomez, Mario, Zeng, Ni, Betsou, Fay, May, Patrick, Skupin, Alexander, Cosma, Antonio, Balling, Rudi, Krüger, Rejko, Ollert, Markus, Hefeng, Feng Q.

“…Neuroinflammation in the brain contributes to the pathogenesis of Parkinson’s disease (PD), but the potential dysregulation of peripheral immunity has not been…”
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New RT-PCR Assay for the Detection of Current and Future SARS-CoV-2 Variants by Marchini, Antonio, Petrillo, Mauro, Parrish, Amy, Buttinger, Gerhard, Tavazzi, Simona, Querci, Maddalena, Betsou, Fay, Elsinga, Goffe, Medema, Gertjan, Abdelrahman, Tamir, Gawlik, Bernd, Corbisier, Philippe

“…Multiple lineages of SARS-CoV-2 have been identified featuring distinct sets of genetic changes that confer to the virus higher transmissibility and ability to…”
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Ice recrystallization inhibitors enable efficient cryopreservation of induced pluripotent stem cells: A functional and transcriptomic analysis by Mommaerts, Kathleen, Okawa, Satoshi, Schmitt, Margaux, Kofanova, Olga, Turner, Tracey R., Ben, Robert N., Del Sol, Antonio, Mathieson, William, Schwamborn, Jens C., Acker, Jason P., Betsou, Fay

“…•Cryopreservation protocols development for induced pluripotent stem cells (iPSCs).•We assessed ice recrystallization inhibitors (IRIs) for iPSCs…”
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Biospecimen Science of Blood for Peripheral Blood Mononuclear Cell (PBMC) Functional Applications by Betsou, Fay, Gaignaux, Amelie, Ammerlaan, Wim, Norris, Philip J., Stone, Mars

“…Purpose of Review Peripheral blood mononuclear cells (PBMCs) are used in a wide variety of preclinical assays. Preanalytical variations can have a devastating…”
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Preanalytical Stability of Antibodies to Pathogenic Antigens by Hodgkinson, Verity S, Egger, Sam, Betsou, Fay, Waterboer, Tim, Pawlita, Michael, Michel, Angelika, Baker, Mark S, Banks, Emily, Sitas, Freddy

“…Serologic testing for antibodies against epitopes from pathogens is a valuable tool for investigating the relationship between infection and disease. This…”
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Differential miRNA and Protein Expression Reveals miR-1285, Its Targets TGM2 and CDH-1, as Well as CD166 and S100A13 as Potential New Biomarkers in Patients with Diabetes Mellitus and Pancreatic Adenocarcinoma by Kolokotronis, Theodoros, Majchrzak-Stiller, Britta, Buchholz, Marie, Mense, Vanessa, Strotmann, Johanna, Peters, Ilka, Skrzypczyk, Lea, Liffers, Sven-Thorsten, Menkene, Louise Massia, Wagner, Mathias, Glanemann, Matthias, Betsou, Fay, Ammerlaan, Wim, Schmidt, Ronny, Schröder, Christoph, Uhl, Waldemar, Braumann, Chris, Höhn, Philipp

“…Early detection of PDAC remains challenging due to the lack of early symptoms and the absence of reliable biomarkers. The aim of the present project was to…”
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The Luxembourg Parkinson's Study: A Comprehensive Approach for Stratification and Early Diagnosis by Hipp, Geraldine, Vaillant, Michel, Diederich, Nico J, Roomp, Kirsten, Satagopam, Venkata P, Banda, Peter, Sandt, Estelle, Mommaerts, Kathleen, Schmitz, Sabine K, Longhino, Laura, Schweicher, Alexandra, Hanff, Anne-Marie, Nicolai, Béatrice, Kolber, Pierre, Reiter, Dorothea, Pavelka, Lukas, Binck, Sylvia, Pauly, Claire, Geffers, Lars, Betsou, Fay, Gantenbein, Manon, Klucken, Jochen, Gasser, Thomas, Hu, Michele T, Balling, Rudi, Krüger, Rejko

“…While genetic advances have successfully defined part of the complexity in Parkinson's disease (PD), the clinical characterization of phenotypes remains…”
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