Search Results - "Betleja, Ewelina"
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A novel Cep120-dependent mechanism inhibits centriole maturation in quiescent cells
Published in eLife (09-05-2018)“…The two centrioles of the centrosome in quiescent cells are inherently asymmetric structures that differ in age, morphology and function. How these asymmetric…”
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Journal Article -
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Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry
Published in Molecular biology of the cell (01-01-2016)“…The establishment of left-right (L-R) asymmetry in vertebrates is dependent on the sensory and motile functions of cilia during embryogenesis. Mutations in…”
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Journal Article -
3
Loss of ARL13 impedes BBSome-dependent cargo export from Chlamydomonas cilia
Published in The Journal of cell biology (03-10-2022)“…The GTPase Arl13b participates in ciliary protein transport, but its contribution to intraflagellar transport (IFT), the main motor-based protein shuttle of…”
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4
Ciliary Trafficking: CEP290 Guards a Gated Community
Published in Current biology (09-11-2010)“…A recent study reveals that the large coiled-coil protein CEP290 is an integral component of the transition zone between the cell body and the cilium and…”
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Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets
Published in Current biology (10-07-2017)“…SYNE1 (synaptic nuclear envelope 1) encodes multiple isoforms of Nesprin1 (nuclear envelope spectrin 1) that associate with the nuclear envelope (NE) through a…”
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Journal Article -
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The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation
Published in Cytoskeleton (Hoboken, N.J.) (31-10-2024)“…Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left-right (LR) patterning of the internal organs…”
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7
Centrosome-dependent microtubule modifications set the conditions for axon formation
Published in Cell reports (Cambridge) (19-04-2022)“…Microtubule (MT) modifications are critical during axon development, with stable MTs populating the axon. How these modifications are spatially coordinated is…”
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Functional characterization of biallelic RTTN variants identified in an infant with microcephaly, simplified gyral pattern, pontocerebellar hypoplasia, and seizures
Published in Pediatric research (01-09-2018)“…Background Biallelic deleterious variants in RTTN , which encodes rotatin, are associated with primary microcephaly, polymicrogyria, seizures, intellectual…”
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Analysis of the gliding machinery in the green alga, Chlamydomonas reinhardtii
Published 01-01-2012“…This dissertation explores two different types of motility associated with the flagella of the unicellular, biflagellate green alga, Chlamydomonas reinhardtii…”
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Dissertation -
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Purification of IFT Particle Proteins and Preparation of Recombinant Proteins for Structural and Functional Analysis
Published in Cilia: Model Organisms and Intraflagellar Transport (2009)“…Intraflagellar transport (IFT) is characterized by a robust bidirectional movement of large proteinaceous particles along the length of eukaryotic cilia and…”
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Book Chapter Journal Article -
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Analysis of the gliding machinery in the green alga, Chlamydomonas reinhardtii
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Dissertation