Search Results - "Betim Pavan, Isadora Carolina"

Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice by Nakandakari, Susana Castelo Branco Ramos, Muñoz, Vitor Rosetto, Kuga, Gabriel Keine, Gaspar, Rafael Calais, Sant'Ana, Marcella Ramos, Pavan, Isadora Carolina Betim, da Silva, Luiz Guilherme Salvino, Morelli, Ana Paula, Simabuco, Fernando Moreira, da Silva, Adelino Sanchez Ramos, de Moura, Leandro Pereira, Ropelle, Eduardo Rochete, Cintra, Dennys Esper, Pauli, José Rodrigo

“…•Short-term HFD consumption increases hippocampal β-Amyloid and Tau phosphorylation.•This process is associated with increased inflammatory, ER stress and…”
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Checking NEKs: Overcoming a Bottleneck in Human Diseases by Peres de Oliveira, Andressa, Kazuo Issayama, Luidy, Betim Pavan, Isadora Carolina, Riback Silva, Fernando, Diniz Melo-Hanchuk, Talita, Moreira Simabuco, Fernando, Kobarg, Jörg

“…In previous years, several kinases, such as phosphoinositide 3-kinase (PI3K), mammalian target of rapamycin (mTOR), and extracellular-signal-regulated kinase…”
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Pomegranate Juice and Peel Extracts are Able to Inhibit Proliferation, Migration and Colony Formation of Prostate Cancer Cell Lines and Modulate the Akt/mTOR/S6K Signaling Pathway by Chaves, Fernanda Machado, Pavan, Isadora Carolina Betim, da Silva, Luiz Guilherme Salvino, de Freitas, Lidia Broglio, Rostagno, Mauricio Ariel, Antunes, Adriane Elisabete Costa, Bezerra, Rosângela Maria Neves, Simabuco, Fernando Moreira

“…Pomegranate ( Punica granatum ) is known to contain polyphenols with many potential health benefits, including anti-tumoral, anti-inflammatory, and…”
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Protective effects of beet (Beta vulgaris) leaves extract against oxidative stress in endothelial cells in vitro by Silva, Luiz Guilherme Salvino, Morelli, Ana Paula, Pavan, Isadora Carolina Betim, Tavares, Mariana Rosolen, Pestana, Nathalie Fortes, Rostagno, Mauricio Ariel, Simabuco, Fernando Moreira, Bezerra, Rosângela Maria Neves

“…Beetroot is an herb used worldwide as a food product, raw material for food industry, ethanol production and source of food coloring. Beet leaves are an…”
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Beetroot and leaf extracts present protective effects against prostate cancer cells, inhibiting cell proliferation, migration, and growth signaling pathways by Mancini, Mariana Camargo Silva, Ponte, Luis Gustavo Saboia, Silva, Cayo Henrique Rocha, Fagundes, Isabella, Pavan, Isadora Carolina Betim, Romeiro, Stefhani Andrioli, Silva, Luiz Guilherme Salvino, Morelli, Ana Paula, Rostagno, Maurício Ariel, Simabuco, Fernando Moreira, Bezerra, Rosangela Maria Neves

“…Beet (Beta vulgaris L.) has high nutritional value, containing bioactive compounds such as betalains and flavonoids. Scientific evidence points to the use of…”
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Anticancer effects of root and beet leaf extracts (Beta vulgaris L.) in cervical cancer cells (HeLa) by Romero, Stefhani Andrioli, Pavan, Isadora Carolina Betim, Morelli, Ana Paula, Mancini, Mariana Camargo Silva, Silva, Luiz Guilherme Salvino, Fagundes, Isabella, Silva, Cayo Henrique Rocha, Ponte, Luis Gustavo Saboia, Rostagno, Mauricio Ariel, Bezerra, Rosângela Maria Neves, Simabuco, Fernando Moreira

“…Cervical cancer is the fourth leading cause of cancer mortality in women worldwide. Beetroot (Beta vulgaris L.) has bioactive compounds that can inhibit the…”
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STAT3 contributes to cisplatin resistance, modulating EMT markers, and the mTOR signaling in lung adenocarcinoma by Morelli, Ana Paula, Tortelli, Tharcísio Citrângulo, Mancini, Mariana Camargo Silva, Pavan, Isadora Carolina Betim, Silva, Luiz Guilherme Salvino, Severino, Matheus Brandemarte, Granato, Daniela Campos, Pestana, Nathalie Fortes, Ponte, Luis Gustavo Saboia, Peruca, Guilherme Francisco, Pauletti, Bianca Alves, dos Santos, Daniel Francisco Guimarães, de Moura, Leandro Pereira, Bezerra, Rosângela Maria Neves, Leme, Adriana Franco Paes, Chammas, Roger, Simabuco, Fernando Moreira

“…•SILAC proteomics approach yielded important cisplatin resistance biomarkers in NSCLC.•Cisplatin resistance upregulated NER-based repair and downregulated mRNA…”
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Molecular mechanisms and pharmacological interventions in the replication cycle of human coronaviruses by Simabuco, Fernando Moreira, Tamura, Rodrigo Esaki, Pavan, Isadora Carolina Betim, Morale, Mirian Galliote, Ventura, Armando Morais

“…SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), as well as SARS-CoV from 2003 along with MERS-CoV from 2012, is a member of the Betacoronavirus…”
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Interactome analysis of the human Cap‐specific mRNA (nucleoside‐2′‐O‐)‐methyltransferase 1 (hMTr1) protein by Simabuco, Fernando Moreira, Pavan, Isadora Carolina Betim, Pestana, Nathalie Fortes, Carvalho, Paulo Costa, Basei, Fernanda Luisa, Campos Granato, Daniela, Paes Leme, Adriana Franco, Zanchin, Nilson Ivo Tonin

“…In a previous study, we have shown that the gene promoter of a protein termed KIAA0082 is regulated by interferon and that this protein interacts with the RNA…”
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On Broken Ne(c)ks and Broken DNA: The Role of Human NEKs in the DNA Damage Response by Pavan, Isadora Carolina Betim, Peres de Oliveira, Andressa, Dias, Pedro Rafael Firmino, Basei, Fernanda Luisa, Issayama, Luidy Kazuo, Ferezin, Camila de Castro, Silva, Fernando Riback, Rodrigues de Oliveira, Ana Luisa, Alves Dos Reis Moura, Lívia, Martins, Mariana Bonjiorno, Simabuco, Fernando Moreira, Kobarg, Jörg

“…NIMA-related kinases, or NEKs, are a family of Ser/Thr protein kinases involved in cell cycle and mitosis, centrosome disjunction, primary cilia functions, and…”
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The Hallmarks of Flavonoids in Cancer by Ponte, Luis Gustavo Saboia, Pavan, Isadora Carolina Betim, Mancini, Mariana Camargo Silva, da Silva, Luiz Guilherme Salvino, Morelli, Ana Paula, Severino, Matheus Brandemarte, Bezerra, Rosangela Maria Neves, Simabuco, Fernando Moreira

“…Flavonoids represent an important group of bioactive compounds derived from plant-based foods and beverages with known biological activity in cells. From the…”
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The Effects of Aging on Rho-Kinase and Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Rats by Muñoz, Vitor Rosetto, Gaspar, Rafael Calais, Kuga, Gabriel Keine, Pavan, Isadora Carolina Betim, Simabuco, Fernando Moreira, da Silva, Adelino Sanchez Ramos, de Moura, Leandro Pereira, Cintra, Dennys Esper, Ropelle, Eduardo Rochete, Pauli, José Rodrigo

“…Abstract The insulin receptor substrate 1 regulates insulin-mediated glucose uptake and is a target of Rho-kinase (Rock); however, the relationship between…”
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Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways by Morelli, Ana Paula, Tortelli, Tharcisio Citrangulo, Jr, Pavan, Isadora Carolina Betim, Silva, Fernando Riback, Granato, Daniela Campos, Peruca, Guilherme Francisco, Pauletti, Bianca Alves, Domingues, Romenia Ramos, Bezerra, Rosangela Maria Neves, de Moura, Leandro Pereira, Leme, Adriana Franco Paes, Chammas, Roger, Simabuco, Fernando Moreira

“…Lung cancer is the leading cause of cancer-associated death worldwide and exhibits intrinsic and acquired therapeutic resistance to cisplatin (CIS). The…”
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Modulation of hypothalamic S6K1 and S6K2 alters feeding behavior and systemic glucose metabolism by Tavares, Mariana Rosolen, Lemes, Simone Ferreira, de Fante, Thais, Saenz de Miera, Cristina, Pavan, Isadora Carolina Betim, Bezerra, Rosangela Maria Neves, Prada, Patricia Oliveira, Torsoni, Marcio Alberto, Elias, Carol Fuzeti, Simabuco, Fernando Moreira

“…The mTOR/S6Ks signaling is one of the intracellular pathways important for metabolic control, acting both peripherally and centrally. In the hypothalamus,…”
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Characterization of the Interaction Between SARS-CoV-2 Membrane Protein (M) and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target by Zambalde, Érika Pereira, Pavan, Isadora Carolina Betim, Mancini, Mariana Camargo Silva, Severino, Matheus Brandemarte, Scudero, Orlando Bonito, Morelli, Ana Paula, Amorim, Mariene Ribeiro, Bispo-Dos-Santos, Karina, Góis, Mariana Marcela, Toledo-Teixeira, Daniel A, Parise, Pierina Lorencini, Mauad, Thais, Dolhnikoff, Marisa, Saldiva, Paulo Hilário Nascimento, Marques-Souza, Henrique, Proenca-Modena, José Luiz, Ventura, Armando Morais, Simabuco, Fernando Moreira

“…SARS-CoV-2 is an emerging virus from the Coronaviridae family and is responsible for the ongoing COVID-19 pandemic. In this work, we explored the previously…”
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NEK6 Regulates Redox Balance and DNA Damage Response in DU-145 Prostate Cancer Cells by Pavan, Isadora Carolina Betim, Basei, Fernanda Luisa, Severino, Matheus Brandemarte, Rosa E Silva, Ivan, Issayama, Luidy Kazuo, Mancini, Mariana Camargo Silva, Góis, Mariana Marcela, da Silva, Luiz Guilherme Salvino, Bezerra, Rosangela Maria Neves, Simabuco, Fernando Moreira, Kobarg, Jörg

“…NEK6 is a central kinase in developing castration-resistant prostate cancer (CRPC). However, the pathways regulated by NEK6 in CRPC are still unclear. Cancer…”
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Maternal high-fat diet stimulates proinflammatory pathway and increases the expression of Tryptophan Hydroxylase 2 (TPH2) and brain-derived neurotrophic factor (BDNF) in adolescent mice hippocampus by Dias, Clarissa Tavares, Curi, Haidar Tafner, Payolla, Tanyara Baliani, Lemes, Simone Ferreira, Betim Pavan, Isadora Carolina, Torsoni, Marcio Alberto, Simabuco, Fernando Moreira, Lambertucci, Rafael Herling, Mendes da Silva, Cristiano

“…Maternal high-fat diet (HFD) consumption can promote a systemic inflammatory condition that may impair the offspring brain development, damaging memory and…”
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Beetroot Root and Leaf Extracts Present Potential Effects Against Prostate Cancer Cells, Inhibiting Cell Proliferation, Migration and Growth Signaling Pathways by Mancini, Mariana, Saboia Ponte, Luis Gustavo, Silva Rocha, Cayo Henrique, Fagundes, Isabella, Betim Pavan, Isadora Carolina, Romero, Stefhani Andrioli, Salvino da Silva, Luiz Guilherme, Morelli, Ana Paula, Rostagno, Maurício Ariel, Simabuco, Fernando Moreira, Bezerra, Rosangela

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