Search Results - "Bethi, Sridhar R"

Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1 by Cheung, Mui, Tangirala, Raghuram S, Bethi, Sridhar R, Joshi, Hemant V, Ariazi, Jennifer L, Tirunagaru, Vijaya G, Kumar, Sanjay

“…Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) plays an important role in triglyceride synthesis and is a target of interest for the treatment of metabolic…”
Get full text

Protein Interactions with Self-Assembled Monolayers Presenting Multimodal Ligands:  A Surface Plasmon Resonance Study by Vutukuru, Srinavya, Bethi, Sridhar R, Kane, Ravi S

“…This paper describes the use of surface plasmon resonance (SPR) spectroscopy and self-assembled monolayers (SAMs) to understand the characteristics of surfaces…”
Get full text

Thiol-Mediated Anchoring of Ligands to Self-Assembled Monolayers for Studies of Biospecific Interactions by Gujraty, Kunal V, Ashton, Randolph, Bethi, Sridhar R, Kate, Sandesh, Faulkner, Christopher J, Jennings, G. Kane, Kane, Ravi S

“…We report a method to immobilize thiol-containing ligands onto self-assembled monolayers (SAMs) of alkanethiolates presenting chloracetylated hexa(ethylene…”
Get full text

Abstract 373: Discovery of selective PI3Kb inhibitors for PTEN-deficient tumors and other indications by Chowdhury, Arnab R., Athisayamani, Jeyaraj D., Mitra, Sayan, Maddi, Srinivas, Adluri, Ram Sudheer, Bethi, Sridhar R., Joshi, Hemant, Tirunagaru, Vijaya G., Gupta, Jang B.

“…Abstract PTEN somatic mutations occur in a large percentage of human cancers, from breast to prostate. Deletions of PTEN e.g. in prostate cancers are…”
Get full text

Surface immobilization of hexa-histidine-tagged adeno-associated viral vectors for localized gene delivery by Jang, J-H, Koerber, J T, Gujraty, K, Bethi, S R, Kane, R S, Schaffer, D V

“…Adeno-associated viral (AAV) vectors, which are undergoing broad exploration in clinical trials, have significant promise for therapeutic gene delivery because…”
Get full text