Search Results - "Bethe, Andrea"

Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A by Fiebig, Timm, Cramer, Johannes T., Bethe, Andrea, Baruch, Petra, Curth, Ute, Führing, Jana I., Buettner, Falk F. R., Vogel, Ulrich, Schubert, Mario, Fedorov, Roman, Mühlenhoff, Martina

“…O -Acetylation of the capsular polysaccharide (CPS) of Neisseria meningitidis serogroup A (NmA) is critical for the induction of functional immune responses,…”
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A Multivalent Adsorption Apparatus Explains the Broad Host Range of Phage phi92: a Comprehensive Genomic and Structural Analysis by SCHWARZER, David, BUETTNER, Falk F. R, LEIMAN, Petr G, GERARDY-SCHAHN, Rita, BROWNING, Christopher, NAZAROV, Sergey, RABSCH, Wolfgang, BETHE, Andrea, OBERBECK, Astrid, BOWMAN, Valorie D, STUMMEYER, Katharina, MÜHLENHOFF, Martina

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from Actinobacillus pleuropneumoniae , Neisseria meningitidis , and Bibersteinia trehalosi by Litschko, Christa, Budde, Insa, Berger, Monika, Bethe, Andrea, Schulze, Julia, Alcala Orozco, E Alberto, Mahour, Reza, Goettig, Peter, Führing, Jana Indra, Rexer, Thomas, Gerardy-Schahn, Rita, Schubert, Mario, Fiebig, Timm

“…Capsule polymers are crucial virulence factors of pathogenic bacteria and are used as antigens in glycoconjugate vaccine formulations. Some Gram-negative…”
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Molecular Cloning and Functional Characterization of Components of the Capsule Biosynthesis Complex of Neisseria meningitidis Serogroup A by Fiebig, Timm, Freiberger, Friedrich, Pinto, Vittoria, Romano, Maria Rosaria, Black, Alan, Litschko, Christa, Bethe, Andrea, Yashunsky, Dmitry, Adamo, Roberto, Nikolaev, Andrei, Berti, Francesco, Gerardy-Schahn, Rita

“…The human pathogen Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis globally. A major virulence factor of Nm is the capsular…”
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Molecular characterization of eukaryotic polysialyltransferase-1 by Eckhardt, Matthias, Mühlenhoff, Martina, Bethe, Andrea, Koopman, Jaap, Frosch, Matthias, Gerardy-Schahn, Rita

“…Polysialic acid (PSA) is a dynamically regulated product of post-translational modification of the neural cell adhesion molecule, NCAM. Presence of the large…”
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Efficient solid-phase synthesis of meningococcal capsular oligosaccharides enables simple and fast chemoenzymatic vaccine production by Fiebig, Timm, Litschko, Christa, Freiberger, Friedrich, Bethe, Andrea, Berger, Monika, Gerardy-Schahn, Rita

“…Neisseria meningitidis serogroups A and X are among the leading causes of bacterial meningitis in the African meningitis belt. Glycoconjugate vaccines,…”
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A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule by Cifuente, Javier O., Schulze, Julia, Bethe, Andrea, Di Domenico, Valerio, Litschko, Christa, Budde, Insa, Eidenberger, Lukas, Thiesler, Hauke, Ramón Roth, Isabel, Berger, Monika, Claus, Heike, D’Angelo, Cecilia, Marina, Alberto, Gerardy-Schahn, Rita, Schubert, Mario, Guerin, Marcelo E., Fiebig, Timm

“…Bacterial capsules have critical roles in host-pathogen interactions. They provide a protective envelope against host recognition, leading to immune evasion…”
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Molecular cloning and functional expression of bacteriophage PK1E-encoded endoneuraminidase Endo NE by Gerardy-Schahn, R, Bethe, A, Brennecke, T, Mühlenhoff, M, Eckhardt, M, Ziesing, S, Lottspeich, F, Frosch, M

“…Homopolymeric alpha-2,8-linked sialic acid (PSA) has been found as a capsular component of sepsis- and meningitis-causing bacterial pathogens, and on…”
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Extending the enzymatic toolbox for heparosan polymerization, depolymerization, and detection by Sulewska, Małgorzata, Berger, Monika, Damerow, Manuela, Schwarzer, David, Buettner, Falk F.R., Bethe, Andrea, Taft, Manuel H., Bakker, Hans, Mühlenhoff, Martina, Gerardy-Schahn, Rita, Priem, Bernard, Fiebig, Timm

“…Heparosan is an acidic polysaccharide expressed as a capsule polymer by pathogenic and commensal bacteria, e.g. by E. coli K5. As a precursor in the…”
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Transition transferases prime bacterial capsule polymerization by Litschko, Christa, Di Domenico, Valerio, Schulze, Julia, Li, Sizhe, Ovchinnikova, Olga G, Voskuilen, Thijs, Bethe, Andrea, Cifuente, Javier O, Marina, Alberto, Budde, Insa, Mast, Tim A, Sulewska, Małgorzata, Berger, Monika, Buettner, Falk F R, Lowary, Todd L, Whitfield, Chris, Codée, Jeroen D C, Schubert, Mario, Guerin, Marcelo E, Fiebig, Timm

“…Capsules are long-chain carbohydrate polymers that envelop the surfaces of many bacteria, protecting them from host immune responses. Capsule biosynthesis…”
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Molecular cloning and functional characterization of components of the capsule biosynthesis complex of Neisseria meningitidis serogroup A: toward in vitro vaccine production by Fiebig, Timm, Freiberger, Friedrich, Pinto, Vittoria, Romano, Maria Rosaria, Black, Alan, Litschko, Christa, Bethe, Andrea, Yashunsky, Dmitry, Adamo, Roberto, Nikolaev, Andrei, Berti, Francesco, Gerardy-Schahn, Rita

“…The human pathogen Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis globally. A major virulence factor of Nm is the capsular…”
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Biochemical and Biophysical Characterization of the Sialyl-/Hexosyltransferase Synthesizing the Meningococcal Serogroup W135 Heteropolysaccharide Capsule by Romanow, Angela, Haselhorst, Thomas, Stummeyer, Katharina, Claus, Heike, Bethe, Andrea, Mühlenhoff, Martina, Vogel, Ulrich, von Itzstein, Mark, Gerardy-Schahn, Rita

“…Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis. Crucial virulence determinants of pathogenic Nm strains are the…”
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Expression Cloning of the Golgi CMP-Sialic Acid Transporter by Eckhardt, Matthias, Mühlenhoff, Martina, Bethe, Andrea, Gerardy-Schahn, Rita

“…Translocation of nucleotide sugars across the membrane of the Golgi apparatus is a prerequisite for the synthesis of complex carbohydrate structures. While…”
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Autocatalytic polysialylation of polysialyltransferase‐1 by Mühlenhoff, M., Eckhardt, M., Bethe, A., Frosch, M., Gerardy‐Schahn, R.

“…Polysialic acid (PSA) is a specific and highly regulated post‐translational modification of the neural cell adhesion molecule NCAM. Synthesis of PSA depends on…”
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Polysialylation of NCAM by a single enzyme by Mühlenhoff, Martina, Eckhardt, Matthias, Bethe, Andrea, Frosch, Matthias, Gerardy-Schahn, Rita

“…The addition of poly-α2,8-N-acetylneuraminic acid (polysialic acid; PSA) to the neural cell adhesion molecule NCAM plays a crucial role in neural development…”
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