Risk Factors Associated with COVID-19 Mortality in the State of Durango, Mexico

The coronavirus disease 2019 (COVID-19) has caused over six million deaths worldwide since its emergence in Wuhan China, factors associated with COVID-19 mortality, such as comorbidities, age, and observed symptomatology still remain a major subject of study. In the present work, a total of 16,345 S...

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Published in:International journal of medical sciences Vol. 20; no. 8; pp. 993 - 999
Main Authors: González Villarreal, Sebastián Eduardo, Salas Pacheco, Sergio Manuel, Vázquez Alaniz, Fernando, Betancourt Conde, María Irene, Salas Pacheco, José Manuel, Castillo Vazquez, Karla Cecilia, Salas Leal, Alma Cristina, Tremillo Maldonado, Omar Alejandro, Rojas Contreras, Juan Antonio, Hernández Cosain, Erik Iván, García Montelongo, Mónica
Format: Journal Article
Language:English
Published: Australia Ivyspring International Publisher Pty Ltd 01-01-2023
Ivyspring International Publisher
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Summary:The coronavirus disease 2019 (COVID-19) has caused over six million deaths worldwide since its emergence in Wuhan China, factors associated with COVID-19 mortality, such as comorbidities, age, and observed symptomatology still remain a major subject of study. In the present work, a total of 16,345 SARS-CoV-2 positive cases from Durango Mexico diagnosed from May 2020 to December 2021 were analyzed to establish an association of COVID-19 mortality with clinical and demographic variables in a case-control study. Selected variables include patient age, smoking status, sex, presence of comorbidities such as hypertension, diabetes and obesity, as well as patient symptomatology such as fever, dyspnea, abdominal pain and diarrhea. Results indicate that among analyzed data, the median age was 43 years; 54% were female, with a mortality rate of 5.66%. Multivariate regression analysis indicated that the comorbidities associated with the highest risk factor were advanced age (>60) with an odds ratio of 4.127 (IC 95%, 3.37-5.05), hypertension with 1.961 (IC 95%, 1.57-2.45), diabetes with 1.753 (IC 95%, 1.39-2.20) and obesity with 1.413 (IC 95%, 1.11-1.78) respectively. On the other hand, the symptom associated with the highest risk factor was dyspnea with an odds ratio of 18.369 (IC 95%, 14.42-23.39). Our data suggests an association between hypertension and old age with COVID-19 mortality. Other findings include the prevalence of dyspnea, polypnea and cyanosis as a major predictor for COVID-19 mortality, as well as lower mortality risks among health workers.
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Competing Interests: The authors have declared that no competing interest exists.
ISSN:1449-1907
1449-1907
DOI:10.7150/ijms.82591