Search Results - "Betül Kaynak, F."
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Synthesis and anticonvulsant screening of 1,2,4-triazole derivatives
Published in Pharmacological reports (01-12-2018)“…Currently available antiepileptic drugs offer limited symptomatic treatment and fail to cure more than 30% of the epileptic seizures. (Arylalkyl)azoles are a…”
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Synthesis and structure-antituberculosis activity relationship of 1H-indole-2,3-dione derivatives
Published in Bioorganic & medicinal chemistry (01-09-2007)“…New series of 5-fluoro-1H-indole-2,3-dione-3-thiosemicarbazones 2a-k and 5-fluoro-1-morpholino/piperidinomethyl-1H-indole-2,3-dione-3-thiosemicarbazones 3a-r…”
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New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABAAR affinity according to molecular modeling studies
Published in European journal of medicinal chemistry (29-11-2016)“…(Arylalkyl)azoles (AAAs) emerged as a novel class of antiepileptic agents with the invention of nafimidone and denzimol. Several AAA derivatives with potent…”
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Discovery of new azoles with potent activity against Candida spp. and Candida albicans biofilms through virtual screening
Published in European journal of medicinal chemistry (01-10-2019)“…Systemic candidiasis is a rampant bloodstream infection of Candida spp. and C. albicans is the major pathogen isolated from infected humans. Azoles, the most…”
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Synthesis of Some Oxime Ether Derivatives of 1-(2-Naphthyl)-2-(1,2,4-triazol-1-yl)ethanone and Their Anticonvulsant and Antimicrobial Activities
Published in Archiv der Pharmazie (Weinheim) (01-09-2006)“…In this study, oxime and oxime ether derivatives of [1‐(2‐naphthyl)‐2‐(1,2,4‐triazol‐1‐yl)ethanone] were prepared as potential anticonvulsant and antimicrobial…”
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Synthesis and antioxidant properties of novel N-methyl-1,3,4-thiadiazol-2-amine and 4-methyl-2H-1,2,4-triazole-3(4H)-thione derivatives of benzimidazole class
Published in Bioorganic & medicinal chemistry (15-04-2008)“…Some novel 1-methyl-4-(2-(2-substitutedphenyl-1H-benzimidazol-1-yl)acetyl)thiosemicarbazides (16a-20a),…”
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New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABA A R affinity according to molecular modeling studies
Published in European journal of medicinal chemistry (29-11-2016)“…(Arylalkyl)azoles (AAAs) emerged as a novel class of antiepileptic agents with the invention of nafimidone and denzimol. Several AAA derivatives with potent…”
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9
Combined Ruthenium(II) and Lipase Catalysis for Efficient Dynamic Kinetic Resolution of Secondary Alcohols. Insight into the Racemization Mechanism
Published in Journal of the American Chemical Society (22-06-2005)“…Pentaphenylcyclopentadienyl ruthenium complexes (3) are excellent catalysts for the racemization of secondary alcohols at ambient temperature. The combination…”
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Combined spectroscopic, XRD crystal structure and DFT studies on 2-(ethylthio)pyrimidine-4,6-diamine
Published in Journal of molecular structure (05-10-2017)“…In this study, the compound 2-(ethylthio)pyrimidine-4,6-diamine (ETPD) was re-synthesized and its single crystals were obtained by slow evaporation of ethanol…”
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Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds
Published in European journal of medicinal chemistry (01-11-2009)“…In this study, a new class of 4-amino-3-substituted-1,2,4-triazole-5-thiones (1-4) and their corresponding condensed derivatives 3,6-disubstituted…”
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Highly Efficient Redox Isomerization of Allylic Alcohols at Ambient Temperature Catalyzed by Novel Ruthenium-Cyclopentadienyl Complexes-New Insight into the Mechanism
Published in Chemistry : a European journal (07-10-2005)“…A range of ruthenium cyclopentadienyl (Cp) complexes have been prepared and used for isomerization of allylic alcohols to the corresponding saturated carbonyl…”
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13
New 2‑Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors
Published in Journal of medicinal chemistry (25-02-2021)“…Thirty compounds having 1-[2-(5-substituted-2-benzoxazolinone-3-yl) acetyl]-3,5-disubstitutedphenyl-2-pyrazoline structure and nine compounds having…”
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14
5-Benzyl-5-phenyl[1,3]dithiolo[4,5-d]-[1,3]dithiole-2-thione
Published in Acta crystallographica. Section C, Crystal structure communications (01-03-2001)“…In the title compound, C(17)H(12)S(5), the dithiole ring bearing the aryl substituents assumes an envelope conformation with the maximum deviation from…”
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3,4-Bis[(4-methoxybenzoyl)methylsulfanyl]thiophene
Published in Acta crystallographica. Section C, Crystal structure communications (01-06-2005)“…A new type of thiophene derivative having α‐thioketone groups at the 3‐ and 4‐positions, viz. the title compound, C22H20O4S3, has been prepared and studied…”
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Crystal structure of [μ-bis(salicylidene)-1,3-propanediaminato]-copper(II)}dibromozinc(II)
Published in Analytical sciences (01-05-2003)“…The title compound is a double oxygen-bridged dimeric heteronuclear metal complex. The coordination around the Cu atom is distorted square-planar involving two…”
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3,4-Bis[(4-methoxybenzoyl)methyl-sulfanyl]thiophene
Published in Acta crystallographica. Section C, Crystal structure communications (01-06-2005)“…A new type of thiophene derivative having alpha-thioketone groups at the 3- and 4-positions, viz. the title compound, C22H20O4S3, has been prepared and studied…”
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18
Crystal Structure of {[μ-Bis(salicylidene)-1,3-propanediaminato]-copper(II)}dibromozinc(II)
Published in Analytical Sciences (01-05-2003)“…The title compound is a double oxygen-bridged dimeric heteronuclear metal complex. The coordination around the Cu atom is distorted square-planar involving two…”
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19
Synthesis of highly functionalized BEDT-TTF analogues incorporating 1,4-dithiin rings from 1,8-diketones
Published in Tetrahedron (10-11-2008)“…Employment of 1,8-diketone ring formation reaction led to the synthesis of tetrathiafulvalene derivatives having diphenyl-1,4-dithiin ring together with…”
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The intramolecular hydrogen bond analysis in biologically active 5-fluoro-1 H -indole-2,3-dione-3-thiosemicarbazones derivatives by experimental and theoretical methods
Published in Acta crystallographica. Section A, Foundations and advances (23-08-2015)“…Abstract only…”
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