Search Results - "Bester, C."
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Failure of Origin Activation in Response to Fork Stalling Leads to Chromosomal Instability at Fragile Sites
Published in Molecular cell (08-07-2011)“…Perturbed DNA replication in early stages of cancer development induces chromosomal instability preferentially at fragile sites. However, the molecular basis…”
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2
Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
Published in Cell (29-04-2011)“…Chromosomal instability in early cancer stages is caused by stress on DNA replication. The molecular basis for replication perturbation in this context is…”
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3
Assessing Acceptability of COVID-19 Vaccine Booster Dose among Adult Americans: A Cross-Sectional Study
Published in Vaccines (Basel) (02-12-2021)“…Given the emergence of breakthrough infections, new variants, and concerns of waning immunity from the primary COVID-19 vaccines, booster shots emerged as a…”
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4
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway
Published in Science (American Association for the Advancement of Science) (17-05-2019)“…Activation of tumor suppressors for the treatment of human cancer has been a long sought, yet elusive, strategy. PTEN is a critical tumor suppressive…”
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Grouped effects estimators in fixed effects models
Published in Journal of econometrics (01-01-2016)“…We consider estimation of nonlinear panel data models with common and individual specific parameters. Fixed effects estimators are known to suffer from the…”
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The complex basis underlying common fragile site instability in cancer
Published in Trends in genetics (01-06-2012)“…Common fragile sites (CFSs) were characterized almost 30 years ago as sites undergoing genomic instability in cancer. Recently, in vitro studies have found…”
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7
model for commercialisation of honeybush tea, an indigenous crop
Published in Acta horticulturae (01-01-2013)“…Honeybush tea, produced from species of the leguminous genus Cyclopia, is one of the traditional South African herbal teas with a long history of regional use…”
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Inference with dependent data using cluster covariance estimators
Published in Journal of econometrics (01-12-2011)“…This paper presents an inference approach for dependent data in time series, spatial, and panel data applications. The method involves constructing t and Wald…”
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9
Option Prices and the Probability of Success of Cash Mergers
Published in Journal of financial econometrics (19-01-2023)“…Abstract We study both theoretically and empirically option prices on firms undergoing a cash merger offer. To estimate the merger’s success probability, we…”
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10
Complementary conservation of South African crop wild relatives for plant improvement
Published in South African journal of botany (01-11-2024)“…•Crop wild relatives are valuable sources of genetic material that needs to be conserved, using both in situ and ex situ methods.•South Africa contains 258…”
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Cyclopia subternata growth, yield, proline and relative water content in response to water deficit stress
Published in Water S. A. (01-01-2023)“…Cyclopia, generally known as honeybush, and belonging to the Fabaceae family, originates from the Cape Floristic Region of the Eastern Cape and Western Cape…”
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Aerial inoculum patterns of Petri disease pathogens in South African vineyards and rootstock mother blocks
Published in Phytopathologia mediterranea (01-12-2020)“…Petri disease is caused by the xylem inhabiting fungi Phaeomoniella (Pa.) chlamydospora and several Phaeoacremonium (Pm.) species. Pruning wounds are known…”
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Pathogenicity and virulence of south African isolates of Venturia inaequalis
Published in European journal of plant pathology (01-09-2022)“…Venturia inaequalis isolates (causing apple scab) vary in pathogenicity when infecting common susceptible apple cultivars. This quantitative effect may be due…”
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Monitoring Cochlear Health With Intracochlear Electrocochleography During Cochlear Implantation: Findings From an International Clinical Investigation
Published in Ear and hearing (01-03-2023)“…Electrocochleography (ECochG) is emerging as a tool for monitoring cochlear function during cochlear implant (CI) surgery. ECochG may be recorded directly from…”
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Interplay between genetic and epigenetic factors governs common fragile site instability in cancer
Published in Cellular and molecular life sciences : CMLS (01-12-2014)“…Common fragile sites (CFSs) are regions within the normal chromosomal structure that were characterized as hotspots for genomic instability in cancer almost…”
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Integration of transcription regulation and functional genomic data reveals lncRNA SNHG6's role in hematopoietic differentiation and leukemia
Published in Journal of biomedical science (28-02-2024)“…Long non-coding RNAs (lncRNAs) are pivotal players in cellular processes, and their unique cell-type specific expression patterns render them attractive…”
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Identification of competing endogenous RNAs of the tumor suppressor gene PTEN: A probabilistic approach
Published in Scientific reports (10-08-2017)“…Regulation by microRNAs (miRNAs) and modulation of miRNA activity are critical components of diverse cellular processes. Recent research has shown that…”
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Controlled Expression of the Dominant Flocculation Genes FLO1, FLO5, and FLO11 in Saccharomyces cerevisiae
Published in Applied and Environmental Microbiology (01-10-2008)“…In many industrial fermentation processes, the Saccharomyces cerevisiae yeast should ideally meet two partially conflicting demands. During fermentation, a…”
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Honeybush ( Cyclopia spp.): From local cottage industry to global markets — The catalytic and supporting role of research
Published in South African journal of botany (01-10-2011)“…Honeybush tea ( Cyclopia spp.), one of the traditional South African herbal teas with a long history of regional use, remained a cottage industry until the…”
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FIXED-b ASYMPTOTICS FOR SPATIALLY DEPENDENT ROBUST NONPARAMETRIC COVARIANCE MATRIX ESTIMATORS
Published in Econometric theory (01-02-2016)“…This paper develops a method for performing inference using spatially dependent data. We consider test statistics formed using nonparametric covariance matrix…”
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