Search Results - "Bestel, Isabelle"

Two-dimensional self-assembly and complementary base-pairing between amphiphile nucleotides on graphite by Bestel, Isabelle, Campins, Nathalie, Marchenko, Alexandr, Fichou, Denis, Grinstaff, Mark W., Barthélémy, Philippe

“…2D supramolecular structures on HOPG by self-assembly of physisorbed amphiphile nucleotides have been successfully imaged by high resolution STM. The…”
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Pharmacological characterization of the human 5‐HT 4(d) receptor splice variant stably expressed in Chinese hamster ovary cells by Mialet, Jeanne, Berque‐Bestel, Isabelle, Sicsic, Sames, Langlois, Michel, Fischmeister, Rodolphe, Lezoualc'h, Frank

“…The recently identified C‐terminal splice variant of the human 5‐HT 4 receptor, the h5‐HT 4(d) receptor, was stably expressed in a CHO cell line at 493±25 fmol…”
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Exploration of the ligand binding site of the human 5‐HT 4 receptor by site‐directed mutagenesis and molecular modeling by Mialet, Jeanne, Dahmoune, Yamina, Lezoualc'h, Frank, Berque‐Bestel, Isabelle, Eftekhari, Pierre, Hoebeke, Johan, Sicsic, Sames, Langlois, Michel, Fischmeister, Rodolphe

“…Among the five human 5‐HT 4 (h5‐HT 4 ) receptor isoforms, the h5‐HT 4(a) receptor was studied with a particular emphasis on the molecular interactions involved…”
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Bivalent ligands as specific pharmacological tools for G protein-coupled receptor dimers by Berque-Bestel, Isabelle, Lezoualc'h, Frank, Jockers, Ralf

“…G protein-coupled receptors (GPCRs) are major drug targets and are organized in dimeric/oligomeric complexes. These dimers may be composed of identical…”
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New insights into the human 5‐HT4 receptor binding site: exploration of a hydrophobic pocket by Rivail, Lucie, Giner, Mireille, Gastineau, Monique, Berthouze, Magali, Soulier, Jean‐Louis, Fischmeister, Rodolphe, Lezoualc'h, Frank, Maigret, Bernard, Sicsic, Sames, Berque‐Bestel, Isabelle

“…A body of evidences suggests that a hydrophobic pocket of the human 5‐HT4 receptor contributes to the high affinity of some bulky 5‐HT4 ligands. A thorough…”
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Pharmacological characterization of the human 5‐HT4(d) receptor splice variant stably expressed in Chinese hamster ovary cells by Mialet, Jeanne, Berque‐Bestel, Isabelle, Sicsic, Sames, Langlois, Michel, Fischmeister, Rodolphe, Lezoualc'h, Frank

“…The recently identified C‐terminal splice variant of the human 5‐HT4 receptor, the h5‐HT4(d) receptor, was stably expressed in a CHO cell line at 493±25 fmol…”
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Isolation of the serotoninergic 5‐HT 4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6‐glial and CHO cell lines by Mialet, Jeanne, Berque‐Bestel, Isabelle, Eftekhari, Pierre, Gastineau, Monique, Giner, Mireille, Dahmoune, Yamina, Donzeau‐Gouge, Patrick, Hoebeke, Johan, Langlois, Michel, Sicsic, Sames, Fischmeister, Rodolphe, Lezoualc'h, Frank

“…RT–PCR technique was used to clone the human 5‐HT 4(e) receptor (h5‐HT 4(e) ) from heart atrium. We showed that this h5‐HT 4(e) receptor splice variant is…”
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Isolation of the serotoninergic 5‐HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6‐glial and CHO cell lines by Mialet, Jeanne, Berque‐Bestel, Isabelle, Eftekhari, Pierre, Gastineau, Monique, Giner, Mireille, Dahmoune, Yamina, Donzeau‐Gouge, Patrick, Hoebeke, Johan, Langlois, Michel, Sicsic, Sames, Fischmeister, Rodolphe, Lezoualc'h, Frank

“…RT–PCR technique was used to clone the human 5‐HT4(e) receptor (h5‐HT4(e)) from heart atrium. We showed that this h5‐HT4(e) receptor splice variant is…”
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Enhancing the photosensitizing activity of natural flavins: Tuning the heavy-atom effect in the isoalloxazine series by Ribes, Jonathan, Bourdeau, Yann, Rascol, Estelle, Bestel, Isabelle, Badarau, Eduard

“…[Display omitted] Structure-photosensitizing activity relationships for a series of flavin analogues were investigated with the final goal of identifying the…”
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Constitutive dimerization of human serotonin 5‐HT4 receptors in living cells by Berthouze, Magali, Ayoub, Mohammed, Russo, Olivier, Rivail, Lucie, Sicsic, Sames, Fischmeister, Rodolphe, Berque-Bestel, Isabelle, Jockers, Ralf, Lezoualc‧h, Frank

“…Serotonin 5‐HT4 receptor isoforms are G protein‐coupled receptors (GPCRs) with distinct pharmacological properties and may represent a valuable target for the…”
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Exploration of the ligand binding site of the human 5‐HT4 receptor by site‐directed mutagenesis and molecular modeling by Mialet, Jeanne, Dahmoune, Yamina, Lezoualc'h, Frank, Berque‐Bestel, Isabelle, Eftekhari, Pierre, Hoebeke, Johan, Sicsic, Sames, Langlois, Michel, Fischmeister, Rodolphe

“…Among the five human 5‐HT4 (h5‐HT4) receptor isoforms, the h5‐HT4(a) receptor was studied with a particular emphasis on the molecular interactions involved in…”
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Hybrid lipid oligonucleotide conjugates: synthesis, self-assemblies and biomedical applications by Patwa, Amit, Gissot, Arnaud, Bestel, Isabelle, Barthélémy, Philippe

“…Hybrid lipid oligonucleotide conjugates are finding more and more biotechnological applications. This short critical review highlights their synthesis,…”
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Three-component one-pot process to propargylic amines and related amide and sulfonamide compounds: application to the construction of 2-(aminomethyl)benzofurans and indoles by Russo, Olivier, Messaoudi, Samir, Hamze, Abdallah, Olivi, Nathanäel, Peyrat, Jean-François, Brion, Jean-Daniel, Sicsic, Sames, Berque-Bestel, Isabelle, Alami, Mouâd

“…An efficient palladium–copper-catalyzed three-component assembling of propargyl halides, aryl or heteroaryl halides, and secondary amines is described. A wide…”
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Tripolar Bolalipids as Key Components of Sustained-Release Drug Delivery Systems by Al Yaman, Khaled, Al Bardawil, Sandy, Ostojic, Maja, Walrant, Astrid, Dolé, François, Vilette, Sandrine, Lecomte, Sophie, Bestel, Isabelle, Badarau, Eduard

“…Controlling passive diffusion through an amphiphilic membrane is a key factor for the development of future smart generations of drug delivery systems. It also…”
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Design of light-responsive amphiphilic self-assemblies: A novel application of the photosensitive diazirine moiety by Saryeddine, Lilian, Hadnutt, Josh, Grélard, Axelle, Morvan, Estelle, Alies, Bruno, Buré, Corinne, Bestel, Isabelle, Badarau, Eduard

“…[Display omitted] Diazirine is one of the smallest photo-sensitive moieties discovered to date. When incorporated in the structure of phospholipids, its…”
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Investigating the photosensitization activities of flavins irradiated by blue LEDs by Ribes, Jonathan, Cossard, Pauline, Al Yaman, Khaled, Bestel, Isabelle, Badarau, Eduard

“…Due to their ability to easily absorb light and to generate highly reactive species, photosensitizers emerged as promising tools in a wide variety of…”
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Flavin-Conjugated Nanobombs: Key Structural Requirements Governing Their Self-Assemblies’ Morphologies by Ribes, Jonathan, Beztsinna, Nataliia, Bailly, Remy, Castano, Sabine, Rascol, Estelle, Taib-Maamar, Nada, Badarau, Eduard, Bestel, Isabelle

“…In contrast to artificial molecules, natural photosensitizers have the benefit of excellent toxicity profiles and of life-compatible activating energy ranges…”
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Amphiphilic Phospholipid-Based Riboflavin Derivatives for Tumor Targeting Nanomedicines by Beztsinna, Nataliia, Tsvetkova, Yoanna, Bartneck, Matthias, Lammers, Twan, Kiessling, Fabian, Bestel, Isabelle

“…Riboflavin (RF) is an essential vitamin for cellular metabolism. Recent studies have shown that RF is internalized through RF transporters, which are highly…”
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In Silico Identification of a Key Residue for Substrate Recognition of the Riboflavin Membrane Transporter RFVT3 by Dilly, Sébastien, Garnier, Mélanie, Solé, Marion, Bailly, Rémi, Taib, Nada, Bestel, Isabelle

“…Because of its specific physicochemical properties (fluorescence, photosensitizing, and redox reactions), vitamin B2, also called riboflavin (RF), has been…”
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Potential Antidepressants Displayed Combined α2-Adrenoceptor Antagonist and Monoamine Uptake Inhibitor Properties by Cordi, Alex A, Berque-Bestel, Isabelle, Persigand, Thierry, Lacoste, Jean-Michel, Newman-Tancredi, Adrian, Audinot, Valerie, Millan, Mark J

“…Classical antidepressants are thought to act by raising monoamine (serotonin and noradrenaline) levels in the brain. This action is generally accomplished…”
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