Search Results - "Bestehorn, Annika"

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  1. 1

    Conceptual Advances in Control of Inflammation by the RNA-Binding Protein Tristetraprolin by Kovarik, Pavel, Bestehorn, Annika, Fesselet, Jeanne

    Published in Frontiers in immunology (17-09-2021)
    “…Regulated changes in mRNA stability are critical drivers of gene expression adaptations to immunological cues. mRNA stability is controlled mainly by…”
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    Journal Article
  2. 2

    HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation by Scinicariello, Sara, Soderholm, Adrian, Schäfer, Markus, Shulkina, Alexandra, Schwartz, Irene, Hacker, Kathrin, Gogova, Rebeca, Kalis, Robert, Froussios, Kimon, Budroni, Valentina, Bestehorn, Annika, Clausen, Tim, Kovarik, Pavel, Zuber, Johannes, Versteeg, Gijs A

    Published in eLife (24-03-2023)
    “…Tristetraprolin (TTP) is a critical negative immune regulator. It binds AU-rich elements in the untranslated-regions of many mRNAs encoding pro-inflammatory…”
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    Journal Article
  3. 3

    The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains by Gomez-Diaz, Carlos, Jonsson, Gustav, Schodl, Katrin, Deszcz, Luiza, Bestehorn, Annika, Eislmayr, Kevin, Almagro, Jorge, Kavirayani, Anoop, Seida, Mayu, Fennell, Lilian M., Hagelkruys, Astrid, Kovarik, Pavel, Penninger, Josef M., Ikeda, Fumiyo

    Published in iScience (19-11-2021)
    “…The Linear Ubiquitin Chain Assembly Complex (LUBAC), composed of HOIP, HOIL-1L, and SHARPIN, promotes tumor necrosis factor (TNF)-dependent NF-κB signaling in…”
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    Journal Article
  4. 4

    An alternative splice variant of human αA-crystallin modulates the oligomer ensemble and the chaperone activity of α-crystallins by Preis, Waldemar, Bestehorn, Annika, Buchner, Johannes, Haslbeck, Martin

    Published in Cell stress & chaperones (01-07-2017)
    “…In humans, ten genes encode small heat shock proteins with lens αA-crystallin and αB-crystallin representing two of the most prominent members. The canonical…”
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    Journal Article
  5. 5

    Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection by Eislmayr, Kevin, Bestehorn, Annika, Morelli, Luisa, Borroni, Martina, Vande Walle, Lieselotte, Lamkanfi, Mohamed, Kovarik, Pavel

    Published in Science advances (04-03-2022)
    “…Interleukin-1α (IL-1α) and IL-1β are inflammatory cytokines with important roles in health and disease. They trigger the same receptor and elicit comparable…”
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    Journal Article
  6. 6

    An alternative splice variant of human [alpha]A-crystallin modulates the oligomer ensemble and the chaperone activity of [alpha]-crystallins by Preis, Waldemar, Bestehorn, Annika, Buchner, Johannes, Haslbeck, Martin

    Published in Cell stress & chaperones (01-07-2017)
    “…In humans, ten genes encode small heat shock proteins with lens [alpha]A-crystallin and [alpha]B-crystallin representing two of the most prominent members. The…”
    Get full text
    Journal Article