Search Results - "Best, O. G."

A novel functional assay using etoposide plus nutlin-3a detects and distinguishes between ATM and TP53 mutations in CLL by Best, O G, Gardiner, A C, Majid, A, Walewska, R, Austen, B, Skowronska, A, Ibbotson, R, Stankovic, T, Dyer, M J S, Oscier, D G

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Oxygen-evoked Na+ transport in rat fetal distal lung epithelial cells by Baines, D. L., Ramminger, S. J., Collett, A., Haddad, J. J. E., Best, O. G., Land, S. C., Olver, R. E., Wilson, S. M.

“…Monolayer cultures of rat fetal distal lung epithelial (FDLE) cells generated larger spontaneous short circuit currents ( I SC ) when maintained (48 h) at…”
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DNA methylation of membrane-bound tyrosine phosphatase genes in acute lymphoblastic leukaemia by Stevenson, W S, Best, O G, Przybylla, A, Chen, Q, Singh, N, Koleth, M, Pierce, S, Kennedy, T, Tong, W, Kuang, S-Q, Garcia-Manero, G

“…Aberrant DNA promoter methylation with associated gene silencing is a common epigenetic abnormality in acute lymphoblastic leukaemia (ALL) and is associated…”
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A subset of Binet stage A CLL patients with TP53 abnormalities and mutated IGHV genes have stable disease by Best, O G, Gardiner, A C, Davis, Z A, Tracy, I, Ibbotson, R E, Majid, A, Dyer, M J S, Oscier, D G

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ZAP‐70 by flow cytometry: A comparison of different antibodies, anticoagulants, and methods of analysis by Best, O. G., Ibbotson, R. E., Parker, A. E., Davis, Z. A., Orchard, J. A., Oscier, D. G.

“…Background: The clinical course of chronic lymphocytic leukaemia (CLL) is variable. ZAP‐70 expression is believed to provide prognostic information. The flow…”
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Oxygen-evoked changes in transcriptional activity of the 5′-flanking region of the human amiloride-sensitive sodium channel (αENaC) gene: role of nuclear factor κB by BAINES, Deborah L., JANES, Mandy, NEWMAN, David J., BEST, Oliver G.

“…Expression of the α-subunit of the amiloride-sensitive sodium channel (αENaC) is regulated by a number of factors in the lung, including oxygen partial…”
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Fludarabine nucleoside induces accumulations of p53, p63 and p73 in the nuclei of human B-lymphoid cell lines, with cytosolic and mitochondrial increases in p53 by Almazi, Juhura G., Mactier, Swetlana, Best, O. Giles, Crossett, Ben, Mulligan, Stephen P., Christopherson, Richard I.

“…Purpose Human Raji cells treated with fludarabine nucleoside (2‐FaraA, 3 μM) undergo apoptosis with accumulation of p53 in the nuclei as multiple…”
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