Search Results - "Bessette, Erin E."

Genetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: Role of the proximal promoter GC-rich region by Englert, Neal A., Turesky, Robert J., Han, Weiguo, Bessette, Erin E., Spivack, Simon D., Caggana, Michele, Spink, David C., Spink, Barbara C.

“…The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, contributes to carcinogenesis through its role in the regulation of cytochrome…”
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Biomonitoring of Carcinogenic Heterocyclic Aromatic Amines in Hair: A Validation Study by Bessette, Erin E, Yasa, Isil, Dunbar, Deborah, Wilkens, Lynne R, Marchand, Loic Le, Turesky, Robert J

“…A facile method was established to measure heterocyclic aromatic amines (HAAs) accumulated in human hair and rodent fur. The samples were digested by base…”
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Investigations of the posttranslational mechanism of arsenite-mediated downregulation of human cytochrome P4501A1 levels: The role of heme oxygenase-1 by Bessette, Erin E., Fasco, Michael J., Pentecost, Brian T., Reilly, Andrew, Kaminsky, Laurence S.

“…Arsenite, an environmental cocontaminant of polycyclic aromatic hydrocarbons (PAHs), diminishes the PAH‐mediated upregulation of human CYP1A1, the enzyme that…”
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MECHANISMS OF ARSENITE-MEDIATED DECREASES IN BENZO[K]FLUORANTHENE-INDUCED HUMAN CYTOCHROME P4501A1 LEVELS IN HEPG2 CELLS by BESSETTE, Erin E, FASCO, Michael J, PENTECOST, Brian T, KAMINSKY, Laurence S

“…Polycyclic aromatic hydrocarbons (PAHs) and heavy metals are often environmental cocontaminants that could interact to alter PAH carcinogenicity. The heavy…”
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Screening for DNA Adducts by Data-Dependent Constant Neutral Loss-Triple Stage Mass Spectrometry with a Linear Quadrupole Ion Trap Mass Spectrometer by Bessette, Erin E, Goodenough, Angela K, Langouët, Sophie, Yasa, Isil, Kozekov, Ivan D, Spivack, Simon D, Turesky, Robert J

“…A two-dimensional linear quadrupole ion trap mass spectrometer (LIT/MS) was employed to simultaneously screen for DNA adducts of environmental, dietary, and…”
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Identification of Carcinogen DNA Adducts in Human Saliva by Linear Quadrupole Ion Trap/Multistage Tandem Mass Spectrometry by Bessette, Erin E, Spivack, Simon D, Goodenough, Angela K, Wang, Tao, Pinto, Shailesh, Kadlubar, Fred F, Turesky, Robert J

“…DNA adducts of carcinogens derived from tobacco smoke and cooked meat were identified by liquid chromatography−electrospray ionization/multistage tandem mass…”
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DNA Adduct Formation of 4-Aminobiphenyl and Heterocyclic Aromatic Amines in Human Hepatocytes by Nauwelaers, Gwendoline, Bessette, Erin E, Gu, Dan, Tang, Yijin, Rageul, Julie, Fessard, Valérie, Yuan, Jian-Min, Yu, Mimi C, Langouët, Sophie, Turesky, Robert J

“…DNA adduct formation of the aromatic amine, 4-aminobiphenyl (4-ABP), a known human carcinogen present in tobacco smoke, and the heterocyclic aromatic amines…”
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Cytochrome P450-Mediated Metabolism and DNA Binding of 2-Amino-1,7-dimethylimidazo[4,5-g]quinoxaline and Its Carcinogenic Isomer 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline in Mice by Turesky, Robert J, Bessette, Erin E, Dunbar, Deborah, Liberman, Rosa G, Skipper, Paul L

“…2-Amino-1,7-dimethylimidazo­[4,5-g]­quinoxaline (MeIgQx) is a recently discovered heterocyclic aromatic amine (HAA) that is formed during the cooking of meats…”
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Mechanisms of regulation of Cyp1A by PAH/metal mixtures by Bessette, Erin E

“…Polycyclic Aromatic Hydrocarbons (PAHs) and heavy metals are frequent environmental co-contaminants. PAHs are carcinogens; a consequence of their bioactivation…”
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Mechanisms of regulation of Cyp1A by PAH/metal mixtures by Bessette, Erin E

“…Polycyclic Aromatic Hydrocarbons (PAHs) and heavy metals are frequent environmental co-contaminants. PAHs are carcinogens; a consequence of their bioactivation…”
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