Search Results - "Besnier, Marie"

Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction by Gueret, Alexandre, Harouki, Najah, Favre, Julie, Galmiche, Guillaume, Nicol, Lionel, Henry, Jean-Paul, Besnier, Marie, Thuillez, Christian, Richard, Vincent, Kolkhof, Peter, Mulder, Paul, Jaisser, Frédéric, Ouvrard-Pascaud, Antoine

“…Mineralocorticoid receptor (MR) antagonists slow down the progression of heart failure after myocardial infarction (MI), but the cell-specific role of MR in…”
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Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition by Aday, Sezin, Zoldan, Janet, Besnier, Marie, Carreto, Laura, Saif, Jaimy, Fernandes, Rui, Santos, Tiago, Bernardino, Liliana, Langer, Robert, Emanueli, Costanza, Ferreira, Lino

“…Several cell-based therapies are under pre-clinical and clinical evaluation for the treatment of ischemic diseases. Poor survival and vascular engraftment…”
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Robust Revascularization in Models of Limb Ischemia Using a Clinically Translatable Human Stem Cell-Derived Endothelial Cell Product by MacAskill, Mark G., Saif, Jaimy, Condie, Alison, Jansen, Maurits A., MacGillivray, Thomas J., Tavares, Adriana A.S., Fleisinger, Lucija, Spencer, Helen L., Besnier, Marie, Martin, Ernesto, Biglino, Giovanni, Newby, David E., Hadoke, Patrick W.F., Mountford, Joanne C., Emanueli, Costanza, Baker, Andrew H.

“…Pluripotent stem cell-derived differentiated endothelial cells offer high potential in regenerative medicine in the cardiovascular system. With the aim of…”
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High-Throughput Measure of Mitochondrial Superoxide Levels as a Marker of Coronary Artery Disease to Accelerate Drug Translation in Patient-Derived Endothelial Cells Using Opera Phenix ® Technology by Lee, Weiqian E, Besnier, Marie, Genetzakis, Elijah, Tang, Owen, Kott, Katharine A, Vernon, Stephen T, Gray, Michael P, Grieve, Stuart M, Kassiou, Michael, Figtree, Gemma A

“…Improved human-relevant preclinical models of coronary artery disease (CAD) are needed to improve translational research and drug discovery. Mitochondrial…”
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Protocol to create phenotypic primary human hepatocyte cultures using the RASTRUM 3D cell model platform by Yee, Christine, Chan, Yik Lung, Utama, Robert, Besnier, Marie, Engel, Martin, Belfiore, Lisa

“…To improve human hepatotoxicity prediction, in vitro liver cell models replicating hepatocyte function, drug metabolism, and toxicity are required. Here, we…”
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Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B‐deficient mice by Besnier, Marie, Galaup, Ariane, Nicol, Lionel, Henry, Jean‐Paul, Coquerel, David, Gueret, Alexandre, Mulder, Paul, Brakenhielm, Ebba, Thuillez, Christian, Germain, Stéphane, Richard, Vincent, Ouvrard‐Pascaud, Antoine

“…The protein tyrosine phosphatase 1B (PTP1B) modulates tyrosine kinase receptors, among which is the vascular endothelial growth factor receptor type 2…”
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Reduction of heart failure by pharmacological inhibition or gene deletion of protein tyrosine phosphatase 1B by Gomez, Elodie, Vercauteren, Magali, Kurtz, Baptiste, Ouvrard-Pascaud, Antoine, Mulder, Paul, Henry, Jean-Paul, Besnier, Marie, Waget, Aurélie, Hooft Van Huijsduijnen, Rob, Tremblay, Michel L, Burcelin, Remy, Thuillez, Christian, Richard, Vincent

“…Abstract Protein tyrosine phosphatase 1B (PTP1B) regulates tyrosine kinase receptor-mediated responses, and especially negatively influences insulin…”
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Selective Vascular Endothelial Protection Reduces Cardiac Dysfunction in Chronic Heart Failure by Maupoint, Julie, Besnier, Marie, Gomez, Elodie, Bouhzam, Najime, Henry, Jean-Paul, Boyer, Olivier, Nicol, Lionel, Mulder, Paul, Martinet, Jérémie, Richard, Vincent

“…Chronic heart failure (CHF) induces endothelial dysfunction in part because of decreased nitric oxide (NO(·)) production, but the direct link between…”
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Patient Endothelial Colony-Forming Cells to Model Coronary Artery Disease Susceptibility and Unravel the Role of Dysregulated Mitochondrial Redox Signalling by Besnier, Marie, Finemore, Meghan, Yu, Christine, Kott, Katharine A., Vernon, Stephen T., Seebacher, Nicole A., Genetzakis, Elijah, Furman, Anamarija, Tang, Owen, Davis, Ryan L., Hansen, Thomas, Psaltis, Peter J., Bubb, Kristen J., Wise, Steven G., Grieve, Stuart M., Di Bartolo, Belinda A., Figtree, Gemma A.

“…Mechanisms involved in the individual susceptibility to atherosclerotic coronary artery disease (CAD) beyond traditional risk factors are poorly understood…”
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miR-15a/-16 Inhibit Angiogenesis by Targeting the Tie2 Coding Sequence: Therapeutic Potential of a miR-15a/16 Decoy System in Limb Ischemia by Besnier, Marie, Shantikumar, Saran, Anwar, Maryam, Dixit, Parul, Chamorro-Jorganes, Aranzazu, Sweaad, Walid, Sala-Newby, Graciela, Madeddu, Paolo, Thomas, Anita C., Howard, Lynsey, Mushtaq, Sobia, Petretto, Enrico, Caporali, Andrea, Emanueli, Costanza

“…MicroRNA-15a (miR-15a) and miR-16, which are transcribed from the miR-15a/miR-16-1 cluster, inhibit post-ischemic angiogenesis. MicroRNA (miRNA) binding to…”
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Role of protein tyrosine phosphatase 1B in cardiovascular diseases by Thiebaut, Pierre-Alain, Besnier, Marie, Gomez, Elodie, Richard, Vincent

“…Abstract Protein Tyrosine Phosphatase 1B (PTP1B) is mostly involved in negative regulation of signaling mediated by Tyrosine Kinase Receptors, especially the…”
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Abstract 13441: Transcriptomic Analysis of Endothelial Colony Forming Cells From the BioHEART-CT Study to Unravel New Biomarkers for Coronary Artery Disease by Ng, Hooi H, Besnier, Marie, Schnitzler, Kirsten, Tran, Andy, Yang, Jean Y, Figtree, Gemma A

“…Coronary artery disease (CAD) remains the leading cause of death worldwide. There are unmet needs for the diagnosis and treatment for patients with CAD,…”
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Abstract 12273: Crispr-Mutation of the Na+-k+ Pump β1-Subunit Protects Against Cardiac Fibrosis and Heart Failure in Mice by Wu, Di, Genetzakis, Elijah, Ng, Hooi H, Barsha, Giannie, Besnier, Marie, Bubb, Kristen, Figtree, Gemma A

“…IntroductionThe Na+-K+ pump controls translocation of Na+ and K+ across the cell membrane which indirectly affects heart muscle contraction. Glutathionylation…”
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Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis by Beltrami, Cristina, Besnier, Marie, Shantikumar, Saran, Shearn, Andrew I.U., Rajakaruna, Cha, Laftah, Abas, Sessa, Fausto, Spinetti, Gaia, Petretto, Enrico, Angelini, Gianni D., Emanueli, Costanza

“…The pericardial fluid (PF) is contained in the pericardial sac surrounding the heart. MicroRNA (miRNA) exchange via exosomes (endogenous nanoparticles)…”
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p75(NTR)-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte-endothelial crosstalk in diabetes after limb ischaemia by Caporali, Andrea, Meloni, Marco, Nailor, Audrey, Mitić, Tijana, Shantikumar, Saran, Riu, Federica, Sala-Newby, Graciela B, Rose, Lorraine, Besnier, Marie, Katare, Rajesh, Voellenkle, Christine, Verkade, Paul, Martelli, Fabio, Madeddu, Paolo, Emanueli, Costanza

“…The communication between vascular endothelial cells (ECs) and pericytes in the microvasculature is fundamental for vascular growth and homeostasis; however,…”
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Abstract 16176: Newly Identified MiR-6770-3p Dramatically Induces Angiogenesis in Human Endothelial Cells While Uncommonly Decreasing Cell Proliferation by Besnier, Marie, Tang, Owen, Genetzakis, Elijah, Finemore, Meghan, Di Bartolo, Belinda, Figtree, Gemma A

“…Micro-RNAs (miRs) are small non-coding RNAs that alter the expression of multiple mRNA targets. Although they participate in physiological processes,…”
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METTL3 Regulates Angiogenesis by Modulating let-7e-5p and miRNA-18a-5p Expression in Endothelial Cells by Chamorro-Jorganes, Aránzazu, Sweaad, Walid K., Katare, Rajesh, Besnier, Marie, Anwar, Maryam, Beazley-Long, N., Sala-Newby, Graciela, Ruiz-Polo, Iñigo, Chandrasekera, Dhananjie, Ritchie, Alison A., Benest, Andrew V., Emanueli, Costanza

“…[Figure: see text]…”
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Abstract 16284: Patient Derived Endothelial Progenitor Cells as a Model to Unravel New Mechanisms of Coronary Artery Disease by Finemore, Meghan, Yu, Christine, Bubb, Kristen J, Kott, Katherine, Di Bartolo, Belinda, Besnier, Marie, Figtree, Gemma A

“…IntroductionEndothelial colony forming cells (ECFCs) are progenitor cells that can differentiate into mature endothelial cells. Ability to culture these cells…”
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miR-210 Enhances the Therapeutic Potential of Bone-Marrow-Derived Circulating Proangiogenic Cells in the Setting of Limb Ischemia by Besnier, Marie, Gasparino, Stefano, Vono, Rosa, Sangalli, Elena, Facoetti, Amanda, Bollati, Valentina, Cantone, Laura, Zaccagnini, Germana, Maimone, Biagina, Fuschi, Paola, Da Silva, Daniel, Schiavulli, Michele, Aday, Sezin, Caputo, Massimo, Madeddu, Paolo, Emanueli, Costanza, Martelli, Fabio, Spinetti, Gaia

“…Therapies based on circulating proangiogenic cells (PACs) have shown promise in ischemic disease models but require further optimization to reach the bedside…”
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Numérisation expérimentale d’un plan-relief by Besnier, Jean-Marie

“…Sur la base d’une coopération scientifique entre le Musée des plans-reliefs et le Conseil régional de Lorraine, service de l’Inventaire, un premier partenariat…”
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