Search Results - "Beskid, George"

Multicenter in vitro comparative study of fluoroquinolones against 25,129 Gram-positive and Gram-negative clinical isolates by Prosser, Barbara La T., Beskid, George

“…In vitro activities of fleroxacin, ciprofloxacin, ofloxacin, and lomefloxacin were evaluated against 25,129 fresh bacterial isolates from 51 US hospital or…”
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Dual-Action Cephalosporins Incorporating a 3'-Tertiary-Amine-Linked Quinolone by Albrecht, Harry A, Beskid, George, Christenson, James G, Deitcher, Kenneth H, Georgopapadakou, Nafsika H, Keith, Dennis D, Konzelmann, Frederick M, Pruess, David L, Chen Wei, Chung

“…We have previously reported that linking quinolones to the cephalosporin 3'-position through an ester bond, a carbamate function, or a bond through a…”
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A multicenter study on the comparative in vitro activity of fleroxacin and three other quinolones: an interim report from 27 centers by Beskid, G, Prosser, B L

“…A multicenter study was designed to compare the in vitro activity of fleroxacin to that of three other oral quinolones (ciprofloxacin, ofloxacin, and…”
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Cephalosporin 3'-quinolone esters with a dual mode of action by Albrecht, Harry A, Beskid, George, Chan, Ka Kong, Christenson, James G, Cleeland, Roy, Deitcher, Kenneth H, Georgopapadakou, Nafsika H, Keith, Dennis D, Pruess, David L

“…According to the generally accepted mechanism by which bacterial enzymes react with cephalosporins, opening of the beta-lactam ring can lead to the expulsion…”
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Dual-action cephalosporins: cephalosporin 3'-quinolone carbamates by Albrecht, Harry A, Beskid, George, Georgopapadakou, Nafsika H, Keith, Dennis D, Konzelmann, Frederick M, Pruess, David L, Rossman, Pamela L, Wei, Chung Chen, Christenson, James G

“…A series of cephalosporins has been prepared in which the 3'-position was linked to the nitrogen of the antibacterial quinolone ciprofloxacin through a…”
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Dual-action cephalosporins: cephalosporin 3'-quaternary ammonium quinolones by Albrecht, Harry A, Beskid, George, Christenson, James G, Durkin, Joanne W, Fallat, Virve, Georgopapadakou, Nafsika H, Keith, Dennis D, Konzelmann, Frederick M, Lipschitz, Ellen R

“…When cephalosporins exert their biological activity by reacting with bacterial enzymes, opening of the beta-lactam ring can lead to expulsion of the…”
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In vivo evaluation of a dual-action antibacterial, Ro 23-9424, compared to cefotaxime and fleroxacin by Beskid, G, Siebelist, J, McGarry, C M, Cleeland, R, Chan, K, Keith, D D

“…The dual-action antibacterial R 23-9424 (desacetylcefotaxime linked to the quinolone fleroxacin) is a new antibacterial agent with excellent in vitro activity…”
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Enteral, oral, and rectal absorption of ceftriaxone using glyceride enhancers by Beskid, G, Unowsky, J, Behl, C R, Siebelist, J, Tossounian, J L, McGarry, C M, Shah, N H, Cleeland, R

“…In vivo models in rodents and primates were used to investigate ways of overcoming the poor oral and rectal absorption of ceftriaxone. The sodium salt of…”
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Effect of medium chain glycerides on enteral and rectal absorption of beta-lactam and aminoglycoside antibiotics by Unowsky, J, Behl, C R, Beskid, G, Sattler, J, Halpern, J, Cleeland, R

“…The rat enteral and rabbit rectal models were utilized to study the effect of Capmul (medium chain glycerides) on the absorption of a selection of beta-lactam…”
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Correlation of the results of antibiotic synergy and susceptibility testing in vitro with results in experimental mouse infections by Isenberg, H D, Sampson-Scherer, J, Cleeland, R, Titsworth, E, Beskid, G, Christenson, J G, DeLorenzo, W F, Unowsky, J

“…Recent clinical isolates (approximately 150 strains) of the family Enterobacteriaceae were examined by agar diffusion, microdilution, and the Autobac automated…”
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STUDIES OF AMYLASE-PRODUCING BACTERIA by OKUKUBO, F, BESKID, G, HOWARD, J M

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