Search Results - "Besecke, Leslie M."

Pituitary Follistatin Regulates Activin-Mediated Production of Follicle-Stimulating Hormone during the Rat Estrous Cycle by Besecke, Leslie M., Guendner, Monika J., Sluss, Patrick A., Polak, Amanda G., Woodruff, Teresa K., Jameson, J. Larry, Bauer-Dantoin, Angela C., Weiss, Jeffrey

“…Abstract Follistatin, an activin-binding protein, plays a key role in the modulation of activin-dependent functions. In the anterior pituitary, activin…”
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Neuropeptide Y Y1-Receptor Stimulation Is Required for Physiological Amplification of Preovulatory Luteinizing Hormone Surges by Leupen, Sarah M., Besecke, Leslie M., Levine, Jon E.

“…Abstract Neuropeptide Y (NPY) has been shown to potentiate the actions of LHRH during the generation of preovulatory LH surges. It is not yet known, however,…”
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Nonpeptide Luteinizing Hormone-Releasing Hormone Antagonists Derived from Erythromycin A:  Design, Synthesis, and Biological Activity of Cladinose Replacement Analogues by Randolph, John T, Waid, Philip, Nichols, Charles, Sauer, Daryl, Haviv, Fortuna, Diaz, Gilbert, Bammert, Gary, Besecke, Leslie M, Segreti, Jason A, Mohning, Kurt M, Bush, Eugene N, Wegner, Craig D, Greer, Jonathan

“…The design and synthesis of a series of 11,12-cyclic carbamate derivatives of 6-O-methylerythromycin A that are novel, nonpeptide LHRH antagonists, is…”
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Effect of novel motilide ABT-229 versus erythromycin and cisapride on gastric emptying in dogs by Cowles, V E, Nellans, H N, Seifert, T R, Besecke, L M, Segreti, J A, Mohning, K M, Faghih, R, Verlinden, M H, Wegner, C D

“…ABT-229 (8,9-anhydro-4"-deoxy-3'-N-desmethyl-3'-N-ethylerythromycin B-6,9-hemiacetal), a synthetic derivative of erythromycin (ERY) with no antibiotic…”
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Pharmacological and endocrine characterization of A-198401, an orally active GnRH antagonist, in intact and castrate male rat models by Besecke, Leslie M., Diaz, Gilbert J., Segreti, Jason A., Mohning, Kurt M., Cybulski, Van A., Rao, Mira, Bush, Eugene N., Randolph, John T., Waid, Philip L., Haviv, Fortuna, Wegner, Craig D., Greer, Jonathan

“…Gonadotropin‐releasing hormone (GnRH) stimulates the synthesis and secretion of the gonadotropins that maintain the reproductive axis in mammals. Efforts have…”
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Inhibin A and inhibin B are inversely correlated to follicle-stimulating hormone, yet are discordant during the follicular phase of the rat estrous cycle, and inhibin A is expressed in a sexually dimorphic manner by Woodruff, T K, Besecke, L M, Groome, N, Draper, L B, Schwartz, N B, Weiss, J

“…Inhibin A and inhibin B are related dimeric protein hormones and endocrine regulators of the reproductive axis. Specifically, inhibin inhibits FSH secretion…”
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Gonadotropin-releasing hormone regulates follicle-stimulating hormone-beta gene expression through an activin/follistatin autocrine or paracrine loop by Besecke, L M, Guendner, M J, Schneyer, A L, Bauer-Dantoin, A C, Jameson, J L, Weiss, J

“…The FSH beta gene is stimulated by low frequency pulses of GnRH, but is unaffected or suppressed when GnRH is applied at higher frequencies or continuously…”
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Neuropeptide Y Y1-Receptor Stimulation Is Required for Physiological Amplification of Preovulatory Luteinizing Hormone Surges1 by Leupen, Sarah M, Besecke, Leslie M, Levine, Jon E

“…Neuropeptide Y (NPY) has been shown to potentiate the actions of LHRH during the generation of preovulatory LH surges. It is not yet known, however, if…”
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Acute increase in responsiveness of luteinizing hormone (LH)-releasing hormone nerve terminals to neuropeptide-Y stimulation before the preovulatory LH surge by Besecke, L M, Levine, J E

“…Neuropeptide-Y (NPY) neurons regulate LH secretion in part through facilitation of LHRH release. We tested the hypothesis that responsiveness of LHRH neurons…”
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Pituitary Follistatin Regulates Activin-Mediated Production of Follicle-Stimulating Hormone during the Rat Estrous Cycle1 by Besecke, Leslie M, Guendner, Monika J, Sluss, Patrick A, Polak, Amanda G, Woodruff, Teresa K, Jameson, J. Larry, Bauer-Dantoin, Angela C, Weiss, Jeffrey

“…Follistatin, an activin-binding protein, plays a key role in the modulation of activin-dependent functions. In the anterior pituitary, activin stimulates the…”
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Amplitude and frequency modulation of pulsatile luteinizing hormone-releasing hormone release by Levine, J E, Chappell, P, Besecke, L M, Bauer-Dantoin, A C, Wolfe, A M, Porkka-Heiskanen, T, Urban, J H

“…1. A variety of neuroendocrine approaches has been used to characterize cellular mechanisms governing luteinizing hormone-releasing hormone (LHRH) pulse…”
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