Search Results - "Berzat, Anastacia C."

Regulation of the Rho Family Small GTPase Wrch-1/RhoU by C-Terminal Tyrosine Phosphorylation Requires Src by Alan, Jamie K., Berzat, Anastacia C., Dewar, Brian J., Graves, Lee M., Cox, Adrienne D.

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Atypical Mechanism of Regulation of the Wrch-1 Rho Family Small GTPase by Shutes, Adam, Berzat, Anastacia C., Cox, Adrienne D., Der, Channing J.

“…Rho family GTPases are GDP/GTP-regulated molecular switches that regulate signaling pathways controlling diverse cellular processes [1, 2, 3]. Wrch-1 was…”
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Transforming Activity of the Rho Family GTPase, Wrch-1, a Wnt-regulated Cdc42 Homolog, Is Dependent on a Novel Carboxyl-terminal Palmitoylation Motif by Berzat, Anastacia C., Buss, Janice E., Chenette, Emily J., Weinbaum, Carolyn A., Shutes, Adam, Der, Channing J., Minden, Audrey, Cox, Adrienne D.

“…Wrch-1 is a Rho family GTPase that shares strong sequence and functional similarity with Cdc42. Like Cdc42, Wrch-1 can promote anchorage-independent growth…”
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Using inhibitors of prenylation to block localization and transforming activity by Berzat, Anastacia C, Brady, Donita C, Fiordalisi, James J, Cox, Adrienne D

“…The proper subcellular localization and biological activity of most Ras and Rho family small GTPases are dependent on their posttranslational modification by…”
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Visual monitoring of post-translational lipid modifications using EGFP-GTPase probes in live cells by Keller, Patricia J., Fiordalisi, James J., Berzat, Anastacia C., Cox, Adrienne D.

“…Modification of small GTPases by lipids is required for their proper subcellular localization and biological activity. Lipids added post-translationally…”
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Biochemical analyses of the Wrch atypical Rho family GTPases by Shutes, Adam, Berzat, Anastacia C, Chenette, Emily J, Cox, Adrienne D, Der, Channing J

“…The Rho family of GTPases comprises a major branch of the Ras superfamily of small GTPases. To date, at least 22 human members have been identified. However,…”
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Farnesylated proteins: how do they get to where they need to go, and how does location regulate their ability to control proliferation, death, transformation and aging? by Cox, Adrienne D., Madigan, James P., Fiordalisi, James J., Der, Channing J., Berzat, Anastacia C., Philips, Mark R., Bivona, Trever, Ahearn, Ian, Quatela, Steven, Capell, Brian C., Erdos, Michael R., Gordon, Leslie B., Varga, Renee, Collins, Francis S.

“…Ras and Rho family small GTPases require post‐translational modification by isoprenoid lipids in order to localize correctly within the cell and to transmit…”
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Posttranslational modifications as regulators of membrane localization and biological activity of the Rho family small GTPase, Wrch-1 by Berzat, Anastacia C

“…Rho proteins are members of the Ras superfamily of small GTPases. They are most well known for their functions in regulating the actin cytoskeleton, but also…”
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Posttranslational modifications as regulators of membrane localization and biological activity of the Rho family small GTPase, Wrch-1 by Berzat, Anastacia C

“…Rho proteins are members of the Ras superfamily of small GTPases. They are most well known for their functions in regulating the actin cytoskeleton, but also…”
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