Search Results - "Bertsche, D."

Synthesis and Activity of a Novel Class of Tribasic Macrocyclic Antibiotics: The Triamilides by Letavic, Michael A., Bronk, Brian S., Bertsche, Camilla D., Casavant, Jeffrey M., Cheng, Hengmiao, Daniel, Kirsten L., George, David M., Hayashi, Shigeru F., Kamicker, Barbara J., Kolosko, Nicole L., Norcia, Laura J.L., Oberton, Vanessa D., Rushing, Margaret A., Santoro, Sheryl L.

“…The stereoselective synthesis of two novel series of tribasic macrocyclic antibiotics with potent in vitro activity against Pasteurella multocida and…”
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Synthesis, stereochemical assignment and biological activity of a novel series of C-4″ modified aza-Macrolides by Bronk, Brian S, Letavic, Michael A, Bertsche, Camilla D, George, David M, Hayashi, Shigeru F, Kamicker, Barbara J, Kolosko, Nicole L, Norcia, Laura J, Rushing, Margaret A, Santoro, Sheryl L, Yang, Bingwei V

“…Modification of the cladinose C-4″ position via manipulation of the corresponding keto derivatives afforded two stereochemically pure series of compounds. The…”
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Azalide 3,6-Ketals: antibacterial activity and structure–Activity relationships of aryl and hetero aryl substituted analogues by Sakya, Subas M, Bertinato, Peter, Pratt, Bryan, Suarez-Contreras, Melani, Lundy, Kristin M, Minich, Martha L, Cheng, Hengmiao, Ziegler, Carl B, Kamicker, Barbara J, Hayashi, Shigeru F, Santoro, Sheryl L, George, David M, Bertsche, Camilla D

“…Aryl and hetero aryl substituted 3,6-ketals of 15-membered azalide analogues were synthesized and were found to have potent in vitro antibacterial activity…”
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Synthesis and SAR of azalide 3,6-ketal aromatic derivatives as potent gram-positive and gram-negative antibacterial agents by Cheng, Hengmiao, Dirlam, John P., Ziegler, Carl B., Lundy, Kristin M., Hayashi, Shigeru F., Kamicker, Barbara J., Dutra, Jason K., Daniel, Kirsten L., Santoro, Sheryl L., George, David M., Bertsche, Camilla D., Sakya, Subas M., Suarez-Contreras, Melani

“…3,6-Ketals of 15-membered azalide pseudoaglycones are a novel series of macrolide antibiotics. The aromatic derivatives of the azalide 3,6-ketals demonstrated…”
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