Search Results - "Bertrand, Sonia"

The SARS-CoV-2 Virus and the Cholinergic System: Spike Protein Interaction with Human Nicotinic Acetylcholine Receptors and the Nicotinic Agonist Varenicline by Carlson, Eric C, Macsai, Marian, Bertrand, Sonia, Bertrand, Daniel, Nau, Jeffrey

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic. Although the…”
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Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor by Spurny, Radovan, Debaveye, Sarah, Farinha, Ana, Veys, Ken, Vos, Ann M., Gossas, Thomas, Atack, John, Bertrand, Sonia, Bertrand, Daniel, Danielson, U. Helena, Tresadern, Gary, Ulens, Chris

“…The α7 nicotinic acetylcholine receptor (nAChR) belongs to the family of pentameric ligand-gated ion channels and is involved in fast synaptic signaling. In…”
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Molecular Characterization of Off-Target Activities of Telithromycin: a Potential Role for Nicotinic Acetylcholine Receptors by BERTRAND, Daniel, BERTRAND, Sonia, NEVEU, Estelle, FERNANDES, Prabhavathi

“…OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines by Spurny, Radovan, Ramerstorfer, Joachim, Price, Kerry, Brams, Marijke, Ernst, Margot, Nury, Hugues, Verheij, Mark, Legrand, Pierre, Bertrand, Daniel, Bertrand, Sonia, Dougherty, Dennis A, de Esch, Iwan J. P, Corringer, Pierre-Jean, Sieghart, Werner, Lummis, Sarah C. R, Ulens, Chris

“…GABA A receptors are pentameric ligand-gated ion channels involved in fast inhibitory neurotransmission and are allosterically modulated by the anxiolytic,…”
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Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors by Bretin, Sylvie, Louis, Caroline, Seguin, Laure, Wagner, Stéphanie, Thomas, Jean-Yves, Challal, Sylvie, Rogez, Nathalie, Albinet, Karine, Iop, Fabrice, Villain, Nadège, Bertrand, Sonia, Krazem, Ali, Bérachochéa, Daniel, Billiald, Stéphanie, Tordjman, Charles, Cordi, Alex, Bertrand, Daniel, Lestage, Pierre, Danober, Laurence

“…S 47445 is a novel positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors (AMPA-PAM). S 47445 enhanced…”
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The CHRNB2 mutation I312M is associated with epilepsy and distinct memory deficits by Bertrand, Daniel, Elmslie, Frances, Hughes, Elaine, Trounce, John, Sander, Thomas, Bertrand, Sonia, Steinlein, Ortrud K.

“…Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy (ADNFLE). Previously, some nAChR mutations have been described that are…”
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Identification of Molluscan Nicotinic Acetylcholine Receptor (nAChR) Subunits Involved in Formation of Cation- and Anion-Selective nAChRs by van Nierop, Pim, Keramidas, Angelo, Bertrand, Sonia, van Minnen, Jan, Gouwenberg, Yvonne, Bertrand, Daniel, Smit, August B

“…Acetylcholine (ACh) is a neurotransmitter commonly found in all animal species. It was shown to mediate fast excitatory and inhibitory neurotransmission in the…”
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Discovery of Potent Positive Allosteric Modulators of the α3β2 Nicotinic Acetylcholine Receptor by a Chemical Space Walk in ChEMBL by Bürgi, Justus J, Awale, Mahendra, Boss, Silvan D, Schaer, Tifany, Marger, Fabrice, Viveros-Paredes, Juan M, Bertrand, Sonia, Gertsch, Jürg, Bertrand, Daniel, Reymond, Jean-Louis

“…While a plethora of ligands are known for the well studied α7 and α4β2 nicotinic acetylcholine receptor (nAChR), only very few ligands address the related α3β2…”
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Discovery of NMDA Glycine Site Inhibitors from the Chemical Universe Database GDB by Nguyen, Kong Thong, Syed, Salahuddin, Urwyler, Stephan, Bertrand, Sonia, Bertrand, Daniel, Reymond, Jean-Louis

“…The first virtual screening search through the entire chemical space of small organic ligands has identified promising ligands as inhibitors of the…”
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Identification and Functional Expression of a Family of Nicotinic Acetylcholine Receptor Subunits in the Central Nervous System of the Mollusc Lymnaea stagnalis by van Nierop, Pim, Bertrand, Sonia, Munno, David W., Gouwenberg, Yvonne, van Minnen, Jan, Spafford, J.David, Syed, Naweed I., Bertrand, Daniel, Smit, August B.

“…We described a family of nicotinic acetylcholine receptor (nAChR) subunits underlying cholinergic transmission in the central nervous system (CNS) of the…”
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A New Chrna4 Mutation with Low Penetrance in Nocturnal Frontal Lobe Epilepsy by Leniger, Tobias, Kananura, Colette, Hufnagel, Andreas, Bertrand, Sonia, Bertrand, Daniel, Steinlein, Ortrud K.

“…Purpose: To identify and characterize the mutation(s) causing nocturnal frontal lobe epilepsy in a German extended family. Methods: Neuronal nicotinic…”
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Probing the reorganization of the nicotinic acetylcholine receptor during desensitization by time-resolved covalent labeling using [3H]AC5, a photoactivatable agonist by Mourot, Alexandre, Rodrigo, Jordi, Kotzyba-Hibert, Florence, Bertrand, Sonia, Bertrand, Daniel, Goeldner, Maurice

“…The structural reorganizations occurring on the nicotinic acetylcholine receptor (nAChR) during activation and subsequent desensitization have been…”
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Dossier : La fabrique de la compensation écologique : controverses et pratiques – La compensation écologique : le point de vue des Conservatoires d’espaces naturels by Mounier, Bruno, Arnauld de Sartre, Xavier, Maury, Marc, Mossant, Pierre, Pirsoul, Lionel, Bertrand, Sonia

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Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities by Eiselé, Jean-Luc, Bertrand, Sonia, Galzi, Jean-Luc, Devillers-Thiéry, Anne, Changeux, Jean-Pierre, Bertrand, Daniel

“…The neuronal nicotinic alpha 7 (nAChR) and 5-hydroxytryptamine (5HT3) receptors are ligand-gated ion channels with a homologous topological organization and…”
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Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic by Galzi, Jean-Luc, Devillers-Thiery, Anne, Hussy, Nicolas, Bertrand, Sonia, Changeux, Jean-Pierre, Bertrand, Daniel

“…Introduction by site-directed mutagenesis of three amino acids from the MII segment of glycine or gamma-aminobutyric acid (GABAA) receptors into the MII…”
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Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the alpha 7 nicotinic acetylcholine receptor by Spurny, Radovan, Debaveye, Sarah, Farinha, Ana, Veys, Ken, Vos, Ann M, Gossas, Thomas, Atack, John, Bertrand, Sonia, Bertrand, Daniel, Danielson, U Helena, Tresadern, Gary, Ulens, Chris

“…The alpha 7 nicotinic acetylcholine receptor (nAChR) belongs to the family of pentameric ligand-gated ion channels and is involved in fast synaptic signaling…”
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Syntheses and biological properties of cysteine-Reactive epibatidine derivatives by Che, Christian, Petit, Grégory, Kotzyba-Hibert, Florence, Bertrand, Sonia, Bertrand, Daniel, Grutter, Thomas, Goeldner, Maurice

“…The synthesis of epibatidine derivatives modified at the 2-position of the pyridine or pyrimidine rings by reactive functions are described for potential…”
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Tropisetron sensitizes α7 containing nicotinic receptors to low levels of acetylcholine in vitro and improves memory-related task performance in young and aged animals by Callahan, Patrick M., Bertrand, Daniel, Bertrand, Sonia, Plagenhoef, Marc R., Terry, Alvin V.

“…Tropisetron, a 5-HT3 receptor antagonist commonly prescribed for chemotherapy-induced nausea and vomiting also exhibits high affinity, partial agonist activity…”
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EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors by Prickaerts, Jos, van Goethem, Nick P., Chesworth, Richard, Shapiro, Gideon, Boess, Frank G., Methfessel, Christoph, Reneerkens, Olga A.H., Flood, Dorothy G., Hilt, Dana, Gawryl, Maria, Bertrand, Sonia, Bertrand, Daniel, König, Gerhard

“…EVP-6124, ( R)-7-chloro- N-quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors…”
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Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC) by Spurny, Radovan, Billen, Bert, Howard, Rebecca J., Brams, Marijke, Debaveye, Sarah, Price, Kerry L., Weston, David A., Strelkov, Sergei V., Tytgat, Jan, Bertrand, Sonia, Bertrand, Daniel, Lummis, Sarah C.R., Ulens, Chris

“…Pentameric ligand-gated ion channels (pLGICs), such as nicotinic acetylcholine, glycine, γ-aminobutyric acid GABAA/C receptors, and the Gloeobacter violaceus…”
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