Search Results - "Bertrand, E"

Reversion of a Parent {130}⟨310⟩_{α^{''}} Martensitic Twinning System at the Origin of {332}⟨113⟩_{β} Twins Observed in Metastable β Titanium Alloys by Castany, P, Yang, Y, Bertrand, E, Gloriant, T

“…In bcc metastable β titanium alloys, and particularly in superelastic alloys, a unique {332}⟨113⟩ twinning system occurs during plastic deformation. However,…”
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Cavities determine the pressure unfolding of proteins by Roche, Julien, Caro, Jose A, Norberto, Douglas R, Barthe, Philippe, Roumestand, Christian, Schlessman, Jamie L, Garcia, Angel E, García-Moreno E., Bertrand, Royer, Catherine A

“…It has been known for nearly 100 years that pressure unfolds proteins, yet the physical basis of this effect is not understood. Unfolding by pressure implies…”
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Protein Dielectric Constants Determined from NMR Chemical Shift Perturbations by Kukic, Predrag, Farrell, Damien, McIntosh, Lawrence P, García-Moreno E, Bertrand, Jensen, Kristine Steen, Toleikis, Zigmantas, Teilum, Kaare, Nielsen, Jens Erik

“…Understanding the connection between protein structure and function requires a quantitative understanding of electrostatic effects. Structure-based…”
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Arginine: Its pKa value revisited by Fitch, Carolyn A, Platzer, Gerald, Okon, Mark, Garcia-Moreno, Bertrand E, McIntosh, Lawrence P

“…Using complementary approaches of potentiometry and NMR spectroscopy, we have determined that the equilibrium acid dissociation constant (pKa value) of the…”
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The pKa Cooperative: A collaborative effort to advance structure-based calculations of pKa values and electrostatic effects in proteins by Nielsen, Jens E., Gunner, M. R., García-Moreno E., Bertrand

“…The pKa Cooperative (http://www.pkacoop.org) was organized to advance development of accurate and useful computational methods for structure‐based calculation…”
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Arginine residues at internal positions in a protein are always charged by Harms, Michael J, Schlessman, Jamie L, Sue, Gloria R, García-Moreno E., Bertrand

“…Many functionally essential ionizable groups are buried in the hydrophobic interior of proteins. A systematic study of Lys, Asp, and Glu residues at 25…”
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Large shifts in pKa values of lysine residues buried inside a protein by Isom, Daniel G, Castañeda, Carlos A, Cannon, Brian R, García-Moreno E., Bertrand

“…Internal ionizable groups in proteins are relatively rare but they are essential for catalysis and energy transduction. To examine molecular determinants of…”
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Charges in the hydrophobic interior of proteins by Isom, Daniel G., Castañeda, Carlos A., Cannon, Brian R., Velu, Priya D., E., Bertrand García-Moreno

“…Charges are inherently incompatible with hydrophobic environments. Presumably for this reason, ionizable residues are usually excluded from the hydrophobic…”
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Large shifts in pK a values of lysine residues buried inside a protein by Isom, Daniel G., Castañeda, Carlos A., Cannon, Brian R., García-Moreno E., Bertrand

“…Internal ionizable groups in proteins are relatively rare but they are essential for catalysis and energy transduction. To examine molecular determinants of…”
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The Notch pathway in colorectal cancer by Vinson, Kaitlyn E., George, Dennis C., Fender, Alexander W., Bertrand, Fred E., Sigounas, George

“…Colorectal cancer (CRC) is the third leading cause of cancer death worldwide. It is also the third most common cancer diagnosis among men, and the second most…”
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Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer by Fender, Alexander W., Nutter, Jennifer M., Fitzgerald, Timothy L., Bertrand, Fred E., Sigounas, George

“…ABSTRACT Colorectal cancer (CRC) is the third leading cause of cancer death in the United States, resulting in an average of 50,000 deaths per year. Surgery…”
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High tolerance for ionizable residues in the hydrophobic interior of proteins by Isom, Daniel G, Cannon, Brian R, Castañeda, Carlos A, Robinson, Aaron, García-Moreno E., Bertrand

“…Internal ionizable groups are quite rare in water-soluble globular proteins. Presumably, this reflects the incompatibility between charges and the hydrophobic…”
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Do Surgical Margins Affect Local Recurrence and Survival in Extremity, Nonmetastatic, High-grade Osteosarcoma? by Bertrand, Todd E., Cruz, Alex, Binitie, Odion, Cheong, David, Letson, G. Douglas

“…Background Long-term survival for all patients with osteosarcoma using current aggressive adjuvant chemotherapy and surgical resection is between 60% and 70%…”
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Structural, energetic, and dynamic responses of the native state ensemble of staphylococcal nuclease to cavity-creating mutations by Roche, Julien, Caro, Jose A., Dellarole, Mariano, Guca, Ewelina, Royer, Catherine A., García-Moreno E., Bertrand, Garcia, Angel E., Roumestand, Christian

“…The effects of cavity‐creating mutations on the structural flexibility, local and global stability, and dynamics of the folded state of staphylococcal nuclease…”
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Conformational Reorganization Coupled to the Ionization of Internal Lys Residues in Proteins by Richman, Daniel E, Majumdar, Ananya, García-Moreno E, Bertrand

“…Ionizable groups buried in the hydrophobic interior of proteins are essential for energy transduction and catalysis. Because the protein interior is usually…”
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Structural and thermodynamic consequences of burial of an artificial ion pair in the hydrophobic interior of a protein by Robinson, Aaron C., Castañeda, Carlos A., Schlessman, Jamie L., García-Moreno E., Bertrand

“…An artificial charge pair buried in the hydrophobic core of staphyiococcal nuclease was engineered by making the V23E and L36K substitutions. Buried…”
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Dielectric Properties of a Protein Probed by Reversal of a Buried Ion Pair by Robinson, Aaron C, Schlessman, Jamie L, García-Moreno E, Bertrand

“…Thirty years ago, Hwang and Warshel suggested that a microenvironment preorganized to stabilize an ion pair would be incapable of reorganizing to stabilize the…”
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Wettability influence on the onset temperature of pool boiling: Experimental evidence onto ultra-smooth surfaces by Bourdon, B., Bertrand, E., Di Marco, P., Marengo, M., Rioboo, R., De Coninck, J.

“…In this article we study systematically the effect of wettability on the onset of boiling on the same nanometrically smooth surface. By grafting different…”
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Investigation of the martensitic transformation and the damping behavior of a superelastic Ti–Ta–Nb alloy by Bertrand, E., Castany, P., Gloriant, T.

“…In this study the α″ stress-induced martensitic transformation and damping behaviour of the superelastic β-Ti–25Ta–25Nb alloy are investigated by tensile tests…”
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Peculiar Thermodynamics of the Second Critical Point in Supercooled Water by Bertrand, C. E, Anisimov, M. A

“…On the basis of the principle of critical-point universality, we examine the peculiar thermodynamics of the liquid–liquid critical point in supercooled water…”
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