Search Results - "Bertoni, Francesco"

BET Proteins as Targets for Anticancer Treatment by Stathis, Anastasios, Bertoni, Francesco

“…Bromodomain and extraterminal domain (BET) proteins are epigenetic readers that regulate gene expression and are involved in cancer pathogenesis. Over the last…”
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The spectrum of MALT lymphoma at different sites: biological and therapeutic relevance by Zucca, Emanuele, Bertoni, Francesco

“…Extranodal marginal zone (MZ) B-cell lymphomas of the mucosa-associated lymphoid tissue (MALT) arise from lymphoid populations that are induced by chronic…”
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Is There a Role for Dual PI3K/mTOR Inhibitors for Patients Affected with Lymphoma? by Tarantelli, Chiara, Lupia, Antonio, Stathis, Anastasios, Bertoni, Francesco

“…The activation of the PI3K/AKT/mTOR pathway is a main driver of cell growth, proliferation, survival, and chemoresistance of cancer cells, and, for this…”
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Editorial: New insights into the mechanisms of resistance to anti-cancer drugs by Bertoni, Francesco, Rapposelli, Simona

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Advances in understanding the pathogenesis of systemic anaplastic large cell lymphomas by Boi, Michela, Zucca, Emanuele, Inghirami, Giorgio, Bertoni, Francesco

“…Summary The currently used 2008 World Health Organization classification recognizes two types of systemic anaplastic large T cell lymphoma according to ALK…”
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Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia by Rossi, Davide, Rasi, Silvia, Spina, Valeria, Bruscaggin, Alessio, Monti, Sara, Ciardullo, Carmela, Deambrogi, Clara, Khiabanian, Hossein, Serra, Roberto, Bertoni, Francesco, Forconi, Francesco, Laurenti, Luca, Marasca, Roberto, Dal-Bo, Michele, Rossi, Francesca Maria, Bulian, Pietro, Nomdedeu, Josep, Del Poeta, Giovanni, Gattei, Valter, Pasqualucci, Laura, Rabadan, Raul, Foà, Robin, Dalla-Favera, Riccardo, Gaidano, Gianluca

“…The identification of new genetic lesions in chronic lymphocytic leukemia (CLL) prompts a comprehensive and dynamic prognostic algorithm including gene…”
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Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer by Chen, Jingjing, Guccini, Ilaria, Di Mitri, Diletta, Brina, Daniela, Revandkar, Ajinkya, Sarti, Manuela, Pasquini, Emiliano, Alajati, Abdullah, Pinton, Sandra, Losa, Marco, Civenni, Gianluca, Catapano, Carlo V., Sgrignani, Jacopo, Cavalli, Andrea, D’Antuono, Rocco, Asara, John M., Morandi, Andrea, Chiarugi, Paola, Crotti, Sara, Agostini, Marco, Montopoli, Monica, Masgras, Ionica, Rasola, Andrea, Garcia-Escudero, Ramon, Delaleu, Nicolas, Rinaldi, Andrea, Bertoni, Francesco, Bono, Johann de, Carracedo, Arkaitz, Alimonti, Andrea

“…The mechanisms by which mitochondrial metabolism supports cancer anabolism remain unclear. Here, we found that genetic and pharmacological inactivation of…”
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KMT2D mutations and TP53 disruptions are poor prognostic biomarkers in mantle cell lymphoma receiving high-dose therapy: a FIL study by Ferrero, Simone, Rossi, Davide, Rinaldi, Andrea, Bruscaggin, Alessio, Spina, Valeria, Eskelund, Christian W, Evangelista, Andrea, Moia, Riccardo, Kwee, Ivo, Dahl, Christina, Di Rocco, Alice, Stefoni, Vittorio, Diop, Fary, Favini, Chiara, Ghione, Paola, Mahmoud, Abdurraouf Mokhtar, Schipani, Mattia, Kolstad, Arne, Barbero, Daniela, Novero, Domenico, Paulli, Marco, Zamò, Alberto, Jerkeman, Mats, da Silva, Maria Gomes, Santoro, Armando, Molinari, Annalia, Ferreri, Andres, Grønbæk, Kirsten, Piccin, Andrea, Cortelazzo, Sergio, Bertoni, Francesco, Ladetto, Marco, Gaidano, Gianluca

“…In recent years, the outcome of mantle cell lymphoma (MCL) has improved, especially in younger patients, receiving cytarabine-containing chemoimmunotherapy and…”
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Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes by Barreca, Marilia, Spanò, Virginia, Montalbano, Alessandra, Cueto, Mercedes, Díaz Marrero, Ana R, Deniz, Irem, Erdoğan, Ayşegül, Lukić Bilela, Lada, Moulin, Corentin, Taffin-de-Givenchy, Elisabeth, Spriano, Filippo, Perale, Giuseppe, Mehiri, Mohamed, Rotter, Ana, P Thomas, Olivier, Barraja, Paola, Gaudêncio, Susana P, Bertoni, Francesco

“…The marine environment is a rich source of biologically active molecules for the treatment of human diseases, especially cancer. The adaptation to unique…”
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Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation by Fabbri, Giulia, Rasi, Silvia, Rossi, Davide, Trifonov, Vladimir, Khiabanian, Hossein, Ma, Jing, Grunn, Adina, Fangazio, Marco, Capello, Daniela, Monti, Sara, Cresta, Stefania, Gargiulo, Ernesto, Forconi, Francesco, Guarini, Anna, Arcaini, Luca, Paulli, Marco, Laurenti, Luca, Larocca, Luigi M, Marasca, Roberto, Gattei, Valter, Oscier, David, Bertoni, Francesco, Mullighan, Charles G, Foá, Robin, Pasqualucci, Laura, Rabadan, Raul, Dalla-Favera, Riccardo, Gaidano, Gianluca

“…The pathogenesis of chronic lymphocytic leukemia (CLL), the most common leukemia in adults, is still largely unknown. The full spectrum of genetic lesions that…”
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The genetics of nodal marginal zone lymphoma by Spina, Valeria, Khiabanian, Hossein, Messina, Monica, Monti, Sara, Cascione, Luciano, Bruscaggin, Alessio, Spaccarotella, Elisa, Holmes, Antony B., Arcaini, Luca, Lucioni, Marco, Tabbò, Fabrizio, Zairis, Sakellarios, Diop, Fary, Cerri, Michaela, Chiaretti, Sabina, Marasca, Roberto, Ponzoni, Maurilio, Deaglio, Silvia, Ramponi, Antonio, Tiacci, Enrico, Pasqualucci, Laura, Paulli, Marco, Falini, Brunangelo, Inghirami, Giorgio, Bertoni, Francesco, Foà, Robin, Rabadan, Raul, Gaidano, Gianluca, Rossi, Davide

“…Nodal marginal zone lymphoma (NMZL) is a rare, indolent B-cell tumor that is distinguished from splenic marginal zone lymphoma (SMZL) by the different pattern…”
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The K9 lymphoma assay allows a genetic subgrouping of canine lymphomas with improved risk classification by Fanelli, Antonella, Licenziato, Luca, Mazzone, Eugenio, Divari, Sara, Rinaldi, Andrea, Marino, Michele, Maga, Ilaria, Bertoni, Francesco, Marconato, Laura, Aresu, Luca

“…We present here the K9 lymphoma assay, a novel 31-gene targeted next-generation sequencing panel designed for genomic profiling of canine lymphoid neoplasms…”
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IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies by Bergaggio, Elisa, Riganti, Chiara, Garaffo, Giulia, Vitale, Nicoletta, Mereu, Elisabetta, Bandini, Cecilia, Pellegrino, Elisa, Pullano, Verdiana, Omedè, Paola, Todoerti, Katia, Cascione, Luciano, Audrito, Valentina, Riccio, Anna, Rossi, Antonio, Bertoni, Francesco, Deaglio, Silvia, Neri, Antonino, Palumbo, Antonio, Piva, Roberto

“…Proteasome inhibitors (PI) are extensively used for the therapy of multiple myeloma (MM) and mantle cell lymphoma. However, patients continuously relapse or…”
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DNA Copy Number Changes in Diffuse Large B Cell Lymphomas by Cascione, Luciano, Aresu, Luca, Baudis, Michael, Bertoni, Francesco

“…Copy number aberrations (CNV/CNA) represent a major contribution to the somatic mutation landscapes in cancers, and their identification can lead to the…”
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DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas by Restelli, Valentina, Lupi, Monica, Chilà, Rosaria, Vagni, Micaela, Tarantelli, Chiara, Spriano, Filippo, Gaudio, Eugenio, Bertoni, Francesco, Damia, Giovanna, Carrassa, Laura

“…The DNA damage response (DDR) kinases ATR, Chk1, and Wee1 play vital roles in the response to replication stress and in maintaining cancer genomic stability…”
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Chronic inflammation and extra-nodal marginal-zone lymphomas of MALT-type by Thieblemont, Catherine, Bertoni, Francesco, Copie-Bergman, Christiane, Ferreri, Andrés J.M, Ponzoni, Maurilio

“…Abstract Extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (MALT) is an indolent B-cell non-Hodgkin lymphoma (NHL) arising in lymphoid…”
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The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation by Rossi, Davide, Spina, Valeria, Deambrogi, Clara, Rasi, Silvia, Laurenti, Luca, Stamatopoulos, Kostas, Arcaini, Luca, Lucioni, Marco, Rocque, Gabrielle B., Xu-Monette, Zijun Y., Visco, Carlo, Chang, Julie, Chigrinova, Ekaterina, Forconi, Francesco, Marasca, Roberto, Besson, Caroline, Papadaki, Theodora, Paulli, Marco, Larocca, Luigi M., Pileri, Stefano A., Gattei, Valter, Bertoni, Francesco, Foà, Robin, Young, Ken H., Gaidano, Gianluca

“…Richter syndrome (RS) represents the development of diffuse large B-cell lymphoma in the context of chronic lymphocytic leukemia. The scarcity of biologic…”
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Novel insights into the genetics and epigenetics of MALT lymphoma unveiled by next generation sequencing analyses by Cascione, Luciano, Rinaldi, Andrea, Bruscaggin, Alessio, Tarantelli, Chiara, Arribas, Alberto J, Kwee, Ivo, Pecciarini, Lorenza, Mensah, Afua A, Spina, Valeria, Chung, Elaine Y L, di Bergamo, Lodovico Terzi, Dirnhofer, Stephan, Tzankov, Alexandar, Miranda, Roberto N, Young, Ken H, Traverse-Glehen, Alexandra, Gaidano, Gianluca, Swerdlow, Steven H, Gascoyne, Randy, Rabadan, Raul, Ponzoni, Maurilio, Bhagat, Govind, Rossi, Davide, Zucca, Emanuele, Bertoni, Francesco

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Mutational landscape of canine B-cell lymphoma profiled at single nucleotide resolution by RNA-seq by Giannuzzi, Diana, Marconato, Laura, Cascione, Luciano, Comazzi, Stefano, Elgendy, Ramy, Pegolo, Sara, Cecchinato, Alessio, Bertoni, Francesco, Aresu, Luca, Ferraresso, Serena

“…The genomic landscape in human B-cell lymphoma has revealed several somatic mutations and potentially relevant germline alterations affecting therapy and…”
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PCSF: An R-package for network-based interpretation of high-throughput data by Akhmedov, Murodzhon, Kedaigle, Amanda, Chong, Renan Escalante, Montemanni, Roberto, Bertoni, Francesco, Fraenkel, Ernest, Kwee, Ivo

“…With the recent technological developments a vast amount of high-throughput data has been profiled to understand the mechanism of complex diseases. The current…”
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