Search Results - "Bertini, Riccardo"

Optical grade bromide-based thin film electrolytes by Melchioni, Nicola, Trupiano, Giacomo, Tofani, Giorgio, Bertini, Riccardo, Mezzetta, Andrea, Bianco, Federica, Guazzelli, Lorenzo, Beltram, Fabio, Pomelli, Christian Silvio, Roddaro, Stefano, Tredicucci, Alessandro, Paolucci, Federico

“…Controlling the charge density in low-dimensional materials with an electrostatic potential is a powerful tool to explore and influence their electronic and…”
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Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief by Moriconi, Alessio, Cunha, Thiago M., Souza, Guilherme R., Lopes, Alexandre H., Cunha, Fernando Q., Carneiro, Victor L., Pinto, Larissa G., Brandolini, Laura, Aramini, Andrea, Bizzarri, Cinzia, Bianchini, Gianluca, Beccari, Andrea R., Fanton, Marco, Bruno, Agostino, Costantino, Gabriele, Bertini, Riccardo, Galliera, Emanuela, Locati, Massimo, Ferreira, Sérgio H., Teixeira, Mauro M., Allegretti, Marcello

“…Significance Persistent pain in inflammatory and neuropathic conditions is often refractory to conventional analgesic therapy, with most patients suffering…”
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Inflammation-Independent Antinociceptive Effects of DF2755A, a CXCR1/2 Selective Inhibitor: A New Potential Therapeutic Treatment for Peripheral Neuropathy Associated to Non-Ulcerative Interstitial Cystitis/Bladder Pain Syndrome by Brandolini, Laura, Aramini, Andrea, Bianchini, Gianluca, Ruocco, Anna, Bertini, Riccardo, Novelli, Rubina, Angelico, Patrizia, Valsecchi, Anna Elisa, Russo, Roberto, Castelli, Vanessa, Cimini, Annamaria, Allegretti, Marcello

“…Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a chronic bladder disease of unknown etiology characterized by urinary frequency and episodic and…”
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Role of the Chemokine Receptor CXCR2 in Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Russo, Remo C, Guabiraba, Rodrigo, Garcia, Cristiana C, Barcelos, Luciola S, Roffe, Ester, Souza, Adriano L. S, Amaral, Flavio A, Cisalpino, Daniel, Cassali, Geovanni D, Doni, Andrea, Bertini, Riccardo, Teixeira, Mauro M

“…Pulmonary fibrosis is characterized by chronic inflammation and excessive collagen deposition. Neutrophils are thought to be involved in the pathogenesis of…”
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Noncompetitive Allosteric Inhibitors of the Inflammatory Chemokine Receptors CXCR1 and CXCR2: Prevention of Reperfusion Injury by Bertini, Riccardo, Allegretti, Marcello, Bizzarri, Cinzia, Moriconi, Alessio, Locati, Massimo, Zampella, Giuseppe, Cervellera, Maria N., Di Cioccio, Vito, Cesta, Maria C., Galliera, Emanuela, Martinez, Fernando O., Di Bitondo, Rosa, Troiani, Giulia, Sabbatini, Vilma, D'Anniballe, Gaetano, Anacardio, Roberto, Cutrin, Juan C., Cavalieri, Barbara, Mainiero, Fabrizio, Strippoli, Raffaele, Villa, Pia, Di Girolamo, Maria, Martin, Franck, Gentile, Marco, Santoni, Angela, Corda, Daniela, Poli, Giuseppe, Mantovani, Alberto, Ghezzi, Pietro, Colotta, Francesco, Dinarello, Charles A.

“…The chemokine CXC ligand 8 (CXCL8)/IL-8 and related agonists recruit and activate polymorphonuclear cells by binding the CXC chemokine receptor 1 (CXCR1) and…”
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Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion by Cugini, Daniela, Azzollini, Nadia, Gagliardini, Elena, Cassis, Paola, Bertini, Riccardo, Colotta, Francesco, Noris, Marina, Remuzzi, Giuseppe, Benigni, Ariela

“…Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion. Ischemia/reperfusion (I/R) injury after…”
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Relevance of Spike/Estrogen Receptor-α interaction for endothelial-based coagulopathy induced by SARS-CoV-2 by Barbieri, Silvia Stella, Cattani, Franca, Sandrini, Leonardo, Grillo, Magda Maria, Amendola, Alessandra, Valente, Carmen, Talarico, Carmine, Iaconis, Daniela, Turacchio, Gabriele, Lucariello, Miriam, Lione, Lucia, Salvatori, Erika, Amadio, Patrizia, Garoffolo, Gloria, Maffei, Mariano, Galli, Francesca, Beccari, Andrea Rosario, Sberna, Giuseppe, Marra, Emanuele, Zoppi, Marica, Michaelides, Michael, Roscilli, Giuseppe, Aurisicchio, Luigi, Bertini, Riccardo, Allegretti, Marcello, Pesce, Maurizio

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Crucial pathophysiological role of CXCR2 in experimental ulcerative colitis in mice by Buanne, Pasquale, Di Carlo, Emma, Caputi, Lorenzo, Brandolini, Laura, Mosca, Marco, Cattani, Franca, Pellegrini, Luigi, Biordi, Leda, Coletti, Gino, Sorrentino, Carlo, Fedele, Guido, Colotta, Francesco, Melillo, Gabriella, Bertini, Riccardo

“…Polymorphonuclear leukocyte infiltration and activation into colonic mucosa are believed to play a pivotal role in mediating tissue damage in human ulcerative…”
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Reparixin, an inhibitor of CXCR2 function, attenuates inflammatory responses and promotes recovery of function after traumatic lesion to the spinal cord by Gorio, Alfredo, Madaschi, Laura, Zadra, Giorgia, Marfia, Giovanni, Cavalieri, Barbara, Bertini, Riccardo, Di Giulio, Anna Maria

“…It has been shown that the blockade of CXCR1 and CXCR2 receptors prevents ischemia/reperfusion damage in several types of vascular beds. Reparixin is a…”
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The interleukin-8 (IL-8/CXCL8) receptor inhibitor reparixin improves neurological deficits and reduces long-term inflammation in permanent and transient cerebral ischemia in rats by Villa, Pia, Triulzi, Sara, Cavalieri, Barbara, Di Bitondo, Rosa, Bertini, Riccardo, Barbera, Sara, Bigini, Paolo, Mennini, Tiziana, Gelosa, Paolo, Tremoli, Elena, Sironi, Luigi, Ghezzi, Pietro

“…Leukocyte infiltration is viewed as a pharmacological target in cerebral ischemia. We previously reported that reparixin, a CXCL8 receptor blocker that…”
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2-Arylpropionic CXC Chemokine Receptor 1 (CXCR1) Ligands as Novel Noncompetitive CXCL8 Inhibitors by Allegretti, Marcello, Bertini, Riccardo, Cesta, Maria Candida, Bizzarri, Cinzia, Di Bitondo, Rosa, Di Cioccio, Vito, Galliera, Emanuela, Berdini, Valerio, Topai, Alessandra, Zampella, Giuseppe, Russo, Vincenzo, Di Bello, Nicoletta, Nano, Giuseppe, Nicolini, Luca, Locati, Massimo, Fantucci, Piercarlo, Florio, Saverio, Colotta, Francesco

“…The CXC chemokine CXCL8/IL-8 plays a major role in the activation and recruitment of polymorphonuclear (PMN) cells at inflammatory sites. CXCL8 activates PMNs…”
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Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2 by Casilli, Federica, Bianchini, Andrea, Gloaguen, Isabelle, Biordi, Leda, Alesse, Edoardo, Festuccia, Claudio, Cavalieri, Barbara, Strippoli, Raffaele, Cervellera, Maria Neve, Bitondo, Rosa Di, Ferretti, Elisabetta, Mainiero, Fabrizio, Bizzarri, Cinzia, Colotta, Francesco, Bertini, Riccardo

“…Repertaxin is a new non-competitive allosteric blocker of interleukin-8 (CXCL8/IL-8) receptors (CXCR1/R2), which by locking CXCR1/R2 in an inactive…”
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Chemokine MIP-2/CXCL2, acting on CXCR2, induces motor neuron death in primary cultures by De Paola, Massimiliano, Buanne, Pasquale, Biordi, Leda, Bertini, Riccardo, Ghezzi, Pietro, Mennini, Tiziana

“…Chemokines are implicated in many diseases of the central nervous system (CNS). Although their primary role is to induce inflammation through the recruitment…”
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Key role of proline‐rich tyrosine kinase 2 in interleukin‐8 (CXCL8/IL‐8)‐mediated human neutrophil chemotaxis by Di Cioccio, Vito, Strippoli, Raffaele, Bizzarri, Cinzia, Troiani, Giulia, Cervellera, Maria Neve, Gloaguen, Isabelle, Colagrande, Antonella, Cattozzo, Elisa Margherita, Pagliei, Sabrina, Santoni, Angela, Colotta, Francesco, Mainiero, Fabrizio, Bertini, Riccardo

“…Summary The signalling pathways leading to CXCL8/IL‐8‐induced human neutrophil migration have not been fully characterized. The present study demonstrates that…”
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Therapeutic inhibition of CXCR1/2: where do we stand? by Sitaru, Sebastian, Budke, Agnes, Bertini, Riccardo, Sperandio, Markus

“…Mounting experimental evidence from in vitro and in vivo animal studies points to an essential role of the CXCL8-CXCR1/2 axis in neutrophils in the…”
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Corticosteroid-independent inhibition of tumor necrosis factor production by the neuropeptide urocortin by Agnello, D, Bertini, R, Sacco, S, Meazza, C, Villa, P, Ghezzi, P

“…Urocortin (UCN) is a neuropeptide homologous with corticotropin-releasing factor (CRF), which has anti-inflammatory activities not all mediated by…”
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Peripheral blood mononuclear cell production of interleukin-8 and IL-8-dependent neutrophil function in hypercholesterolemic patients by Porreca, Ettore, Sergi, Rita, Baccante, Giovanna, Reale, Marcella, Orsini, Luciano, Di Febbo, Concetta, Caselli, Gianfranco, Cuccurullo, Franco, Bertini, Riccardo

“…Interleukin-8 is a cytokine produced by mononuclear cells that is involved in polymorphonuclear neutrophil leukocyte (PMN) recruitment and activation. Several…”
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The chemokine receptors CXCR1/CXCR2 modulate antigen‐induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature by Coelho, Fernanda M., Pinho, Vanessa, Amaral, Flávio A., Sachs, Daniela, Costa, Vívian V., Rodrigues, David H., Vieira, Angélica T., Silva, Tarcília A., Souza, Daniele G., Bertini, Riccardo, Teixeira, Antônio L., Teixeira, Mauro M.

“…Objective The chemokine receptors CXCR1 and CXCR2 play a role in mediating neutrophil recruitment and neutrophil‐dependent injury in several models of…”
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ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets by Bizzarri, Cinzia, Beccari, Andrea Rosario, Bertini, Riccardo, Cavicchia, Michela Rita, Giorgini, Simona, Allegretti, Marcello

“…ELR+ CXC chemokines, by direct interaction with their cell surface receptors CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2), are…”
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Quantitative analysis of the CD4+ T cell response to therapeutic antibodies in healthy donors using a novel T cell:PBMC assay by Schultz, Heidi S, Reedtz-Runge, Stine Louise, Bäckström, B Thomas, Lamberth, Kasper, Pedersen, Christian R, Kvarnhammar, Anne M

“…Many biopharmaceuticals (BPs) are known to be immunogenic in the clinic, which can result in modified pharmacokinetics, reduced efficacy, allergic reactions…”
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