Search Results - "Bertina, R.M"

Microparticle‐associated tissue factor activity, venous thromboembolism and mortality in pancreatic, gastric, colorectal and brain cancer patients by THALER, J., AY, C., MACKMAN, N., BERTINA, R. M., KAIDER, A., MAROSI, C., KEY, N. S., BARCEL, D. A., SCHEITHAUER, W., KORNEK, G., ZIELINSKI, C., PABINGER, I.

“…Background:  Tissue factor (TF) expression by tumors contributes to tumor growth. Release of TF‐positive microparticles (MPs) may contribute to venous…”
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Atomic force microscopy: a novel approach to the detection of nanosized blood microparticles by YUANA, Y., OOSTERKAMP, T. H., BAHATYROVA, S., ASHCROFT, B., GARCIA RODRIGUEZ, P., BERTINA, R. M., OSANTO, S.

“…See also Freyssinet J‐M, Toti F. Membrane microparticle determination: at least seeing what’s being sized! This issue, pp 311–4. Summary.  Background:…”
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Microparticle‐associated tissue factor activity: a link between cancer and thrombosis? by TESSELAAR, M. E. T., ROMIJN, F. P. H. T. M., VAN DER LINDEN, I. K., PRINS, F. A., BERTINA, R. M., OSANTO, S.

“…Background: Cancer, in particular mucinous adenocarcinoma, is associated with venous thromboembolism (VTE). Tissue factor (TF), initiator of coagulation, plays…”
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Functional Analysis of Two Haplotypes of the Human Endothelial Protein C Receptor Gene by Medina, P, Navarro, S, Bonet, E, Martos, L, Estellés, A, Bertina, R.M, Vos, H.L, España, F

“…OBJECTIVE—To confirm the effect of the endothelial protein receptor gene (PROCR) haplotypes H1 and H3 on venous thromboembolism (VTE), to study their effect on…”
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Genome‐wide linkage scan in affected sibling pairs identifies novel susceptibility region for venous thromboembolism: Genetics In Familial Thrombosis study by Visser, M.C.H., Minkelen, R., Marion, V., Heijer, M., Eikenboom, J., Vos, H.L., Slagboom, P.E., Houwing‐Duistermaat, J.J., Rosendaal, F.R., Bertina, R.M.

“…Summary Background Venous thromboembolism (VTE) is a multicausal disorder involving environmental and genetic risk factors. In many thrombophilic families the…”
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Plasma levels of microparticle-associated tissue factor activity in patients with clinically suspected pulmonary embolism by Garcia Rodriguez, P, Eikenboom, H.C.J, Tesselaar, M.E.T, Huisman, M.V, Nijkeuter, M, Osanto, S, Bertina, R.M

“…Abstract Introduction Microparticles (MPs) carrying active tissue factor (TF) have been detected in the plasma of cancer patients in particular in those…”
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von Willebrand factor and its propeptide: the influence of secretion and clearance on protein levels and the risk of venous thrombosis by NOSSENT, A. Y., VAN MARION, V., VAN TILBURG, N. H., ROSENDAAL, F. R., BERTINA, R. M., VAN MOURIK, J. A., EIKENBOOM, H. C. J.

“…Background and objectives: Elevated levels of factor (F)VIII are associated with an increased risk of thrombosis. FVIII levels are determined mainly by von…”
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C0121: In Vitro Functional Analysis of the H1 Haplotype of the Human Endothelial Protein C Receptor Gene (PROCR) by Bonet, E, Martos, L, Navarro Martinez, S, Ramón, L.A, España, F, Bertina, R.M, Vos, H.L, Medina, P

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Determinants of the APTT‐ and ETP‐based APC sensitivity tests by VISSER, M. C. H., HYLCKAMA VLIEG, A., TANS, G., ROSING, J., DAHM, A. E. A., SANDSET, P. M., ROSENDAAL, F. R., BERTINA, R. M.

“…Background: A reduced sensitivity for activated protein C (APC) is associated with an increased risk of venous thrombosis even in the absence of the factor…”
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C0116: Functional Analysis of Two Haplotypes of the Human Endothelial Protein C Receptor Gene (PROCR) by Bonet, E, Martos, L, Ramón, L.A, Ferrando, F, Vayá, A, Mira, Y, Bonanad, S, Estellés, A, Bertina, R.M, Vos, H.L, España, F, Medina, P, Navarro Rosales, S

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Dimerization and multimerization defects of von Willebrand factor due to mutated cysteine residues by Tjernberg, P., Vos, H. L., Castaman, G., Bertina, R. M., Eikenboom, J. C. J.

“…In patients classified with type 1 and type 3 von Willebrand disease missense mutations resulting in the loss of cysteine residues in the D3‐domain…”
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Matrix Metalloproteinase-9 Gene −1562C/T Polymorphism Mitigates Preeclampsia by Coolman, M, de Maat, M, Van Heerde, W.L, Felida, L, Schoormans, S, Steegers, E.A.P, Bertina, R.M, de Groot, C.J.M

“…Abstract Although the aetiology of preeclampsia is unknown, there is substantial evidence that it finds its roots in abnormal placentation. Prerequisites for…”
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Increased risk of venous thrombosis in carriers of hereditary protein C deficiency defect by Allaart, C F, Poort, S R, Rosendaal, F R, Reitsma, P H, Bertina, R M, Briët, E

“…The relevance of heterozygosity for hereditary protein C deficiency as a risk factor for venous thrombosis has been disputed because heterozygotes without…”
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A new functional assay of thrombin activatable fibrinolysis inhibitor by GUIMARÃES, A. H. C., BERTINA, R. M., RIJKEN, D. C.

“…New thrombin activatable fibrinolysis inhibitor (TAFI) assays are necessary for studying the role of this fibrinolysis inhibitor in cardiovascular disease. The…”
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Ischemic stroke in young patients with activated protein C resistance : a report of three cases belonging to three different kindreds by SIMIONI, P, DE RONDE, H, PRANDONI, P, SALADINI, M, BERTINA, R. M, GIROLAMI, A

“…A new pathological condition termed "activated protein C (APC) resistance" has recently been reported to be the most common hereditary blood coagulation…”
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Functional characterization of transcription factor binding sites for HNF1‐alpha, HNF3‐beta (FOXA2), HNF4‐alpha, Sp1 and Sp3 in the human prothrombin gene enhancer by Ceelie, H., Spaargaren‐van Riel, C. C., De Jong, M., Bertina, R. M., Vos, H. L.

“…Background: Prothrombin is a key component in blood coagulation. Overexpression of prothrombin leads to an increased risk of venous thrombosis. Therefore, the…”
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Venous Thrombosis — The Interaction of Genes and Environment by Bertina, R.M, Rosendaal, F.R

“…Venous thrombosis is the obstruction of the circulation by clots that have been formed locally in the veins or have been released from a thrombus elsewhere…”
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Microparticle‐associated tissue factor activity in cancer patients with and without thrombosis by TESSELAAR, M. E. T., ROMIJN, F. P. H. T. M., VAN DER LINDEN, I. K., BERTINA, R. M., OSANTO, S.

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Inhibition of thrombin‐mediated factor V activation contributes to the anticoagulant activity of fibrinogen γ by Omarova, F., Uitte De Willige, S., Ariëns, R. A. S., Rosing, J., Bertina, R. M., Castoldi, E.

“…Summary Background Besides its role in blood clotting, fibrinogen exerts a poorly understood anticoagulant function by binding thrombin and modulating its…”
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Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor by VAN VLIET, H. A. A. M., BERTINA, R. M., DAHM, A. E. A., ROSENDAAL, F. R., ROSING, J., MORTEN SANDSET, P., HELMERHORST, F. M.

“…Background: Oral contraceptives (OC) containing different types of progestogens induce different sensitivities to activated protein C (APC) measured with the…”
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