Search Results - "Berthou, F"

CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people by Quiñones, L, Lucas, D, Godoy, J, Cáceres, D, Berthou, F, Varela, N, Lee, K, Acevedo, C, Martı́nez, L, Aguilera, A.M, Gil, L

“…CYP1A1, CYP2E1 and GSTM1 polymorphisms were evaluated in Chilean healthy controls and lung cancer patients. In the Chilean healthy group, frequencies of CYP1A1…”
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Susceptibility and exposure biomarkers in people exposed to PAHs from diesel exhaust by Adonis, M, Martı́nez, V, Riquelme, R, Ancic, P, González, G, Tapia, R, Castro, M, Lucas, D, Berthou, F, Gil, L

“…Xenobiotic metabolizing enzymes, especially CYP1A1 and GSTM1, are involved in the activation and conjugation of PAHs and are controlled by polymorphic genes…”
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P2096 Implication de la kinase Tpl2 dans l’expression de COX-2 et la synthèse des prostaglandines induites par les cytokines inflammatoires dans les adipocytes by Berthou, F, Ceppo, F, Cormont, M, Tanti, J.-F

“…Introduction L’obésité est associée à une inflammation du tissu adipeux qui est impliquée dans le développement de la résistance à l’insuline. Les…”
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Requirement for omega and (omega;-1)-hydroxylations of fatty acids by human cytochromes P450 2E1 and 4A11 by Adas, F, Salaün, J P, Berthou, F, Picart, D, Simon, B, Amet, Y

“…Human liver microsomes and recombinant human P450 have been used as enzyme source in order to better understand the requirement for the optimal rate of omega…”
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Involvement of cytochrome P450 3A4 in N-dealkylation of buprenorphine in human liver microsomes by Iribarne, Christelle, Picart, Daniel, Dréano, Yvonne, Bail, Jean-Pierre, Berthou, François

“…Buprenorphine is a long acting analgesic of the opiate family. Recently, it has been proposed for the opioid dependency treatment at a large scale. The drug is…”
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Inhibition of methadone and buprenorphine N-dealkylations by three HIV-1 protease inhibitors by IRIBARNE, C, BERTHOU, F, CARLHANT, D, DREANO, Y, PICART, D, LOHEZIC, F, RICHE, C

“…Ritonavir, indinavir, and saquinavir, all human immunodeficiency virus-1 protease inhibitors with a potent antiviral effect during triple therapy, are…”
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Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations by Quiñones, L, Berthou, F, Varela, N, Simon, B, Gil, L, Lucas, D

“…Many investigators have reported an association between genetic polymorphisms of cytochromes P-450 CYP2E1, CYP1A1 or glutathione S-transferase Mu ( GSTM1) and…”
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Influence of genetic polymorphisms of CYP1A1 and GSTM1 on the urinary levels of 1-hydroxypyrene by Apostoli, P, Neri, G, Lucas, D, Manno, M, Berthou, F

“…The aim of the present study is to evaluate the influence of the genetic polymorphism of two enzymes involved in the biotransformation of xenobiotics,…”
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P143 Effet anti-inflammatoire de l’insuline et du resvératrol sur l’expression de Tpl2 induite par IL-1 – dans les adipocytes by Berthou, F, Ceppo, F, Grémeaux, T, Cormont, M, Tanti, J.F

“…Introduction L’obésité est associée à une inflammation du tissu adipeux laquelle participe à l’installation d’une résistance adipocytaire à l’insuline et à un…”
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High performance liquid chromatography of fatty acid metabolites: Improvement of sensitivity by radiometric, fluorimetric and mass spectrometric methods by Amet, Y, Adas, F, Berthou, F

“…To get a better understanding and knowledge of microsomal cytochrome P450 involvement in the metabolism of fatty acids, e.g. lauric and oleic acids, high…”
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In vitro interactions between fluoxetine or fluvoxamine and methadone or buprenorphine by Iribarne, C, Picart, D, Dréano, Y, Berthou, F

“…Summary— Methadone and buprenorphine, widely used in the treatment of opioid abuse, are metabolized by cytochrome P450 3A4, while fluoxetine and fluvoxamine,…”
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Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes by Kerlan, V, Dreano, Y, Bercovici, J P, Beaune, P H, Floch, H H, Berthou, F

“…Kinetics of the 2- and 4-hydroxylations of estradiol (E2) by human liver microsomal samples were studied to determine the major P450 isoform involved in these…”
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Interspecies variations in fatty acid hydroxylations involving cytochromes P450 2E1 and 4A by Adas, F, Berthou, F, Salaün, J.P, Dréano, Y, Amet, Y

“…The liver microsomal fractions of seven mammalian species including rat, dog, monkey, hamster, mouse, gerbil and humans, catalyzed the hydroxylation of…”
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CYTOCHROME P-450 2E1 ACTIVITY AND OXIDATIVE STRESS IN ALCOHOLIC PATIENTS by Dupont, I., Bodénez, P., Berthou, F., Simon, B., Bardou, L. G., Lucas, D.

“…As cytochrome P-450 2E1 (CYP2E1) induction was related to oxidative stress in experimental models, the aim of this study was to investigate the relationship…”
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Interaction of methadone with substrates of human hepatic cytochrome P450 3A4 by Iribarne, C., Dréano, Y., Bardou, L.G., Ménez, J.F., Berthou, F.

“…Methadone, a synthetic drug, is one of the most widely used drugs for opiate dependency treatment. This drug has been demonstrated to be extensively…”
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Evidence for the involvement of several cytochromes P-450 in the first steps of caffeine metabolism by human liver microsomes by Berthou, F, Flinois, J P, Ratanasavanh, D, Beaune, P, Riche, C, Guillouzo, A

“…Caffeine biotransformation and four monooxygenase activities involving cytochrome P-450IA2, namely ethoxy- and methoxyresorufin O-dealkylases, phenacetin…”
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Biodistribution study of phosphonolipids: a class of non-viral vectors efficient in mice lung-directed gene transfer by Delépine, P., Guillaume, C., Montier, T., Clément, J. C., Yaouanc, J. J., Des Abbayes, H., Berthou, F., Le Pape, A., Férec, C.

“…Background A multitude of cationic lipids have been synthesized since they were first proposed for use in gene therapy. Cationic lipids are able to efficiently…”
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Genetic repeat polymorphism in the regulating region of CYP2E1 : Frequency and relationship with enzymatic activity in alcoholics by PLEE-GAUTIER, E, FORESTO, F, FERRARA, R, BODENEZ, P, SIMON, B, MANNO, M, BERTHOU, F, LUCAS, D

“…Differences in the regulatory region of the CYP2E1 gene could be responsible for the interindividual variation in the cytochrome P-450 2E1 (CYP2E1) involved in…”
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Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic caucasians by Lucas, D, Ménez, C, Floch, F, Gourlaouen, Y, Sparfel, O, Joannet, I, Bodénez, P, Jezequel, J, Gouérou, H, Berthou, F, Bardou, L G, Ménez, J F

“…Genetic polymorphisms of various cytochromes P450 have recently been described and could be implicated in the individual susceptibility of alcoholics to…”
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Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1 by Amet, Y., Berthou, F., Baird, S., Dreano, Y., Bail, J.P., Menez, J.F.

“…The (ω-1)-hydroxylation of lauric acid (11-OH-LA), a model substrate of fatty acids, was previously shown to be due to CYP2E1 in rat liver microsomes. The…”
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