Search Results - "Berthold, Frank"

Advances in Risk Classification and Treatment Strategies for Neuroblastoma by Pinto, Navin R, Applebaum, Mark A, Volchenboum, Samuel L, Matthay, Katherine K, London, Wendy B, Ambros, Peter F, Nakagawara, Akira, Berthold, Frank, Schleiermacher, Gudrun, Park, Julie R, Valteau-Couanet, Dominique, Pearson, Andrew D J, Cohn, Susan L

“…Risk-based treatment approaches for neuroblastoma have been ongoing for decades. However, the criteria used to define risk in various institutional and…”
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Revisions to the International Neuroblastoma Response Criteria: A Consensus Statement From the National Cancer Institute Clinical Trials Planning Meeting by Park, Julie R, Bagatell, Rochelle, Cohn, Susan L, Pearson, Andrew D, Villablanca, Judith G, Berthold, Frank, Burchill, Susan, Boubaker, Ariane, McHugh, Kieran, Nuchtern, Jed G, London, Wendy B, Seibel, Nita L, Lindwasser, O Wolf, Maris, John M, Brock, Penelope, Schleiermacher, Gudrun, Ladenstein, Ruth, Matthay, Katherine K, Valteau-Couanet, Dominique

“…Purpose More than two decades ago, an international working group established the International Neuroblastoma Response Criteria (INRC) to assess treatment…”
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Are network growth and the contributions to congresses associated with publication success? A pediatric oncology model by Berthold, Frank, Bartenhagen, Christoph, Krempel, Lothar

“…The consistent focus of 'Advances in Neuroblastoma Research' congresses on the topic neuroblastoma sets it as a model for a circumscribed scientific community…”
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Role of Surgery in the Treatment of Patients With Stage 4 Neuroblastoma Age 18 Months or Older at Diagnosis by Simon, Thorsten, Häberle, Beate, Hero, Barbara, von Schweinitz, Dietrich, Berthold, Frank

“…Although intensive multimodal treatment has improved the prognosis of patients with metastatic neuroblastoma, the impact of primary tumor resection on outcome…”
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Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma by Powers, John T., Tsanov, Kaloyan M., Pearson, Daniel S., Roels, Frederik, Spina, Catherine S., Ebright, Richard, Seligson, Marc, de Soysa, Yvanka, Cahan, Patrick, Theißen, Jessica, Tu, Ho-Chou, Han, Areum, Kurek, Kyle C., LaPier, Grace S., Osborne, Jihan K., Ross, Samantha J., Cesana, Marcella, Collins, James J., Berthold, Frank, Daley, George Q.

“…Poor prognosis in neuroblastoma is associated with genetic amplification of MYCN . MYCN is itself a target of let-7 , a tumour suppressor family of microRNAs…”
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THROMBOTECT - a randomized study comparing low molecular weight heparin, antithrombin and unfractionated heparin for thromboprophylaxis during induction therapy of acute lymphoblastic leukemia in children and adolescents by Greiner, Jeanette, Schrappe, Martin, Claviez, Alexander, Zimmermann, Martin, Niemeyer, Charlotte, Kolb, Reinhard, Eberl, Wolfgang, Berthold, Frank, Bergsträsser, Eva, Gnekow, Astrid, Lassay, Elisabeth, Vorwerk, Peter, Lauten, Melchior, Sauerbrey, Axel, Rischewski, Johannes, Beilken, Andreas, Henze, Günter, Korte, Wolfgang, Möricke, Anja

“…Thromboembolism is a serious complication of induction therapy for childhood acute lymphoblastic leukemia. We prospectively compared the efficacy and safety of…”
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Clinical Significance of Tumor-Associated Inflammatory Cells in Metastatic Neuroblastoma by ASGHARZADEH, Shahab, SALO, Jill A, WAKAMATSU, Peter, VILLABLANCA, Judith G, KREISSMAN, Susan G, MATTHAY, Katherine K, SHIMADA, Hiroyuki, LONDON, Wendy B, SPOSTO, Richard, SEEGER, Robert C, JI, Lingyun, OBERTHUER, André, FISCHER, Matthias, BERTHOLD, Frank, HADJIDANIEL, Michael, LIU, Cathy Wei-Yao, METELITSA, Leonid S, PIQUE-REGI, Roger

“…Children diagnosed at age ≥ 18 months with metastatic MYCN-nonamplified neuroblastoma (NBL-NA) are at high risk for disease relapse, whereas those diagnosed at…”
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Treatment and outcome of Ganglioneuroma and Ganglioneuroblastoma intermixed by Decarolis, Boris, Simon, Thorsten, Krug, Barbara, Leuschner, Ivo, Vokuhl, Christian, Kaatsch, Peter, von Schweinitz, Dietrich, Klingebiel, Thomas, Mueller, Ingo, Schweigerer, Lothar, Berthold, Frank, Hero, Barbara

“…Ganglioneuroma (GN) and ganglioneuroblastoma intermixed (GNBI) are mature variants of neuroblastic tumors (NT). It is still discussed whether incomplete…”
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Clinical and Biologic Features Predictive of Survival After Relapse of Neuroblastoma: A Report From the International Neuroblastoma Risk Group Project by LONDON, Wendy B, CASTEL, Victoria, MATTHAY, Katherine K, MONCLAIR, Tom, AMBROS, Peter F, PEARSON, Andrew D. J, COHN, Susan L, BERTHOLD, Frank, NAKAGAWARA, Akira, LADENSTEIN, Ruth L, IEHARA, Tomoko

“…Survival after neuroblastoma relapse is poor. Understanding the relationship between clinical and biologic features and outcome after relapse may help in…”
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Complete surgical resection improves outcome in INRG high-risk patients with localized neuroblastoma older than 18 months by Fischer, Janina, Pohl, Alexandra, Volland, Ruth, Hero, Barbara, Dübbers, Martin, Cernaianu, Grigore, Berthold, Frank, von Schweinitz, Dietrich, Simon, Thorsten

“…Although several studies have been conducted on the role of surgery in localized neuroblastoma, the impact of surgical timing and extent of primary tumor…”
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Lack of immunocytological GD2 expression on neuroblastoma cells in bone marrow at diagnosis, during treatment, and at recurrence by Schumacher‐Kuckelkorn, Roswitha, Volland, Ruth, Gradehandt, Anke, Hero, Barbara, Simon, Thorsten, Berthold, Frank

“…Background Loss of disialoganglioside 2 (GD2) expression in neuroblastoma (NB) bone marrow cells has been reported in rare cases. This study investigated…”
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Comparing presentations and outcomes of children with cancer: a study between a lower-middle-income country and a high-income country by Farrag, Ahmed, Ghazaly, Mohamed Hamdy, Mohammed, Khaled, Volland, Ruth, Hero, Barbara, Berthold, Frank

“…Abstract Background Substantial progress has been achieved in managing childhood cancers in many high-income countries (HICs). In contrast, survival rates in…”
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Iodine-123 Metaiodobenzylguanidine Scintigraphy Scoring Allows Prediction of Outcome in Patients With Stage 4 Neuroblastoma: Results of the Cologne Interscore Comparison Study by DECAROLIS, Boris, SCHNEIDER, Christina, HERO, Barbara, SIMON, Thorsten, VOLLAND, Ruth, ROELS, Frederik, DIETLEIN, Markus, BERTHOLD, Frank, SCHMIDT, Matthias

“…Radioiodinated metaiodobenzylguanidine ((123)I-mIBG) scintigraphy is an established imaging method in neuroblastoma. Semiquantitative scoring systems have been…”
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Localized Infant Neuroblastomas Often Show Spontaneous Regression: Results of the Prospective Trials NB95-S and NB97 by HERO, Barbara, SIMON, Thorsten, SPITZ, Ruediger, ERNESTUS, Karen, GNEKOW, Astrid K, SCHEEL-WALTER, Hans-Guenther, SCHWABE, Dirk, SCHILLING, Freimut H, BENZ-BOHM, Gabriele, BERTHOLD, Frank

“…The excellent prognosis of localized neuroblastoma in infants, the overdiagnosis observed in neuroblastoma screening studies, and several case reports of…”
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Phase II Window Study on Rituximab in Newly Diagnosed Pediatric Mature B-Cell Non-Hodgkin's Lymphoma and Burkitt Leukemia by MEINHARDT, Andrea, BURKHARDT, Birgit, KLAPPER, Wolfram, ATTARBASCHI, Andishe, SCHRAPPE, Martin, REITER, Alfred, ZIMMERMANN, Martin, BORKHARDT, Arndt, KONTNY, Udo, KLINGEBIEL, Thomas, BERTHOLD, Frank, JANKA-SCHAUB, Gritta, KLEIN, Christoph, KABICKOVA, Edita

“…The activity of rituximab in pediatric B-cell non-Hodgkin's lymphoma (B-NHL) has not yet been determined. We conducted a phase II window study to examine…”
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Towards a turning point of neuroblastoma therapy by Tonini, Gian Paolo, Nakagawara, Akira, Berthold, Frank

“…Highlights ► The low survival of high-risk neuroblastoma patients suggests a turning point of therapy. ► Personalized medicine is based on knowledge of…”
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Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy by Simon, Thorsten, Hero, Barbara, Faldum, Andreas, Handgretinger, Rupert, Schrappe, Martin, Klingebiel, Thomas, Berthold, Frank

“…The treatment of high-risk neuroblastoma patients consists of multimodal induction therapy to achieve remission followed by consolidation therapy to prevent…”
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Revised risk estimation and treatment stratification of low- and intermediate-risk neuroblastoma patients by integrating clinical and molecular prognostic markers by Oberthuer, André, Juraeva, Dilafruz, Hero, Barbara, Volland, Ruth, Sterz, Carolina, Schmidt, Rene, Faldum, Andreas, Kahlert, Yvonne, Engesser, Anne, Asgharzadeh, Shahab, Seeger, Robert, Ohira, Miki, Nakagawara, Akira, Scaruffi, Paola, Tonini, Gian Paolo, Janoueix-Lerosey, Isabelle, Delattre, Olivier, Schleiermacher, Gudrun, Vandesompele, Jo, Speleman, Frank, Noguera, Rosa, Piqueras, Marta, Bénard, Jean, Valent, Alexander, Avigad, Smadar, Yaniv, Isaac, Grundy, Richard G, Ortmann, Monika, Shao, Chunxuan, Schwab, Manfred, Eils, Roland, Simon, Thorsten, Theissen, Jessica, Berthold, Frank, Westermann, Frank, Brors, Benedikt, Fischer, Matthias

“…To optimize neuroblastoma treatment stratification, we aimed at developing a novel risk estimation system by integrating gene expression-based classification…”
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Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification by OBERTHUER, André, BERTHOLD, Frank, SCHWAB, Manfred, BRORS, Benedikt, WESTERMANN, Frank, FISCHER, Matthias, WARNAT, Patrick, HERO, Barbara, KAHLERT, Yvonne, SPITZ, Rudiger, ERNESTUS, Karen, KONIG, Rainer, HAAS, Stefan, EILS, Roland

“…To develop a gene expression-based classifier for neuroblastoma patients that reliably predicts courses of the disease. Two hundred fifty-one neuroblastoma…”
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Neuroblastoma: biology and molecular and chromosomal pathology by Schwab, Manfred, Westermann, Frank, Hero, Barbara, Berthold, Frank

“…Neuroblastoma is the most frequently occurring solid tumour in children, with an incidence of 1.3 cases per 100000 children aged 0-14 years. Despite many…”
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