Search Results - "Bertele, Daniela"

Transient apoptosis inhibition in donor stem cells improves hematopoietic stem cell transplantation by Kollek, Matthias, Voigt, Gesina, Molnar, Christian, Murad, Fabronia, Bertele, Daniela, Krombholz, Christopher Felix, Bohler, Sheila, Labi, Verena, Schiller, Stefan, Kunze, Mirjam, Geley, Stephan, Niemeyer, Charlotte M, Garcia-Saez, Ana, Erlacher, Miriam

“…During hematopoietic stem cell transplantation, a substantial number of donor cells are lost because of apoptotic cell death. Transplantation-associated…”
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Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2-/-γc-/- mice by Krombholz, Christopher Felix, Aumann, Konrad, Kollek, Matthias, Bertele, Daniela, Fluhr, Silvia, Kunze, Mirjam, Niemeyer, Charlotte M, Flotho, Christian, Erlacher, Miriam

“…Juvenile myelomonocytic leukemia is a clonal malignant disease affecting young children. Current cure rates, even with allogeneic hematopoietic stem cell…”
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Preclinical evaluation of 4-methylthiobutyl isothiocyanate on liver cancer and cancer stem cells with different p53 status by Lamy, Evelyn, Hertrampf, Anke, Herz, Corinna, Schüler, Julia, Erlacher, Miriam, Bertele, Daniela, Bakare, Adekunle, Wagner, Meike, Weiland, Timo, Lauer, Ulrich, Drognitz, Oliver, Huber, Roman, Rohn, Sascha, Giesemann, Torsten, Mersch-Sundermann, Volker

“…Isothiocyanates from plants of the order Brassicales are considered promising cancer chemotherapeutic phytochemicals. However, their selective cytotoxicity on…”
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Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3‐only proteins Bim and Bmf by Labi, Verena, Bertele, Daniela, Woess, Claudia, Tischner, Denise, Bock, Florian J., Schwemmers, Sven, Pahl, Heike L., Geley, Stephan, Kunze, Mirjam, Niemeyer, Charlotte M., Villunger, Andreas, Erlacher, Miriam

“…Anti‐apoptotic Bcl‐2 family members are critical for the regulation of haematopoietic stem and progenitor cell (HSPC) survival. Little is known about the role…”
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Targeting Aberrant PI3K/Akt Activation by PI103 Restores Sensitivity to TRAIL-Induced Apoptosis in Neuroblastoma by OPEL, Daniela, NAUMANN, Ivonne, SCHNEIDER, Maxi, BERTELE, Daniela, DEBATIN, Klaus-Michael, FULDA, Simone

“…Because we recently identified Akt activation as a novel poor prognostic indicator in neuroblastoma, we investigated whether phosphoinositide 3'-kinase (PI3K)…”
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Transient Bcl-XL Overexpression in Donor Stem Cells Increases Efficacy of Hematopoietic Stem Cell Transplantation without Increasing the Risk of Leukemogenesis by Erlacher, Miriam, Kollek, Matthias, Voigt, Gesina, Bertele, Daniela, Krombholz, Felix, Schiller, Stefan, Garcia-Saez, Ana, Geley, Stephan, Villunger, Andreas, Niemeyer, Charlotte M

“…Hematopoietic stem cell transplantation (HSCT) is the only curative treatment for many hematological and immunological diseases but is hampered by the risk of…”
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B‐cell signaling in persistent polyclonal B lymphocytosis (PPBL) by Voelxen, Nadine, Wehr, Claudia, Gutenberger, Sylvia, Keller, Baerbel, Erlacher, Miriam, Dominguez‐Conde, Cecilia, Bertele, Daniela, Emmerich, Florian, Pantic, Milena, Jennings, Stefanie, Rakhmanov, Mirzokhid, Foerster, Christian, Martens, Uwe M, Platzbecker, Uwe, Peter, Hans‐Hartmut, Fisch, Paul, Boztug, Kaan, Eibel, Hermann, Salzer, Ulrich, Warnatz, Klaus

“…Persistent polyclonal B lymphocytosis (PPBL) is a benign hematological disorder characterized by a selective expansion of circulating polyclonal marginal zone…”
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Lack of the BH3-Only Proteins Bim, Bmf and Puma In Haematopoietic Stem and Progenitor Cells Facilitates Early Reconstitution and Long Term Haematopoiesis by Erlacher, Miriam, Bertele, Daniela, Woess, Claudia, Niemeyer, Charlotte Marie, Villunger, Andreas, Labi, Verena

“…Abstract 1542 During haematopoietic stem cell transplantation (HSCT) the transplanted haematopoietic stem and progenitor cells (HSPC) suffer a transient…”
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Preclinical Evaluation of 4-Methylthiobutyl Isothiocyanate on Liver Cancer and Cancer Stem Cells with Different p53 Status. e70846 by Lamy, Evelyn, Hertrampf, Anke, Herz, Corinna, Schueler, Julia, Erlacher, Miriam, Bertele, Daniela, Bakare, Adekunle, Wagner, Meike, Weiland, Timo, Lauer, Ulrich

“…Isothiocyanates from plants of the order Brassicales are considered promising cancer chemotherapeutic phytochemicals. However, their selective cytotoxicity on…”
Get full text