Search Results - "Bershadsky, A. D."

Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion by Alieva, N. O., Efremov, A. K., Hu, S., Oh, D., Chen, Z., Natarajan, M., Ong, H. T., Jégou, A., Romet-Lemonne, G., Groves, J. T., Sheetz, M. P., Yan, J., Bershadsky, A. D.

“…Filopodia, dynamic membrane protrusions driven by polymerization of an actin filament core, can adhere to the extracellular matrix and experience both external…”
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Molecular requirements for the effect of neuregulin on cell spreading, motility and colony organization by CHAUSOVSKY, A, WATERMAN, H, ELBAUM, M, YARDEN, Y, GEIGER, B, BERSHADSKY, A. D

“…Neuregulin can trigger morphogenetic signals in cells both in vivo and in culture through the activation of receptors from the ErbB family. We have ectopically…”
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Latrunculin-A increases outflow facility in the monkey by PETERSON, J. A, BAOHE TIAN, BERSHADSKY, A. D, VOLBERG, T, GANGNON, R. E, SPECTOR, I, GEIGER, B, KAUFMAN, P. L

“…To determine the effect of Latrunculin (LAT)-A, a macrolide that binds to G-actin, which leads to the disassembly of actin filaments, on shape, junctions, and…”
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Focal Contacts as Mechanosensors: Externally Applied Local Mechanical Force Induces Growth of Focal Contacts by an mDia1-Dependent and ROCK-Independent Mechanism by Riveline, Daniel, Zamir, Eli, Balaban, Nathalie Q., Schwarz, Ulrich S., Ishizaki, Toshimasa, Narumiya, Shuh, Kam, Zvi, Geiger, Benjamin, Bershadsky, Alexander D.

“…The transition of cell-matrix adhesions from the initial punctate focal complexes into the mature elongated form, known as focal contacts, requires GTPase Rho…”
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Disruption of the Golgi Apparatus by Brefeldin A Blocks Cell Polarization and Inhibits Directed Cell Migration by Bershadsky, Alexander D., Futerman, Anthony H.

“…The role of the Golgi apparatus in the motile activity of fibroblasts was examined with brefeldin A (BFA), which disrupts the Golgi apparatus in a variety of…”
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Molecular interactions in the submembrane plaque of cell-cell and cell-matrix adhesions by Geiger, B, Yehuda-Levenberg, S, Bershadsky, A D

“…Adhesion of cells to their neighbors or to the extracellular matrix has multiple effects on cell shape, dynamics and fate. The most obvious and direct one is…”
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Intermediate filament collapse is an ATP-dependent and actin-dependent process by HOLLENBECK, P. J, BERSHADSKY, A. D, PLETJUSHKINA, O. Y, TINT, I. S, VASILIEV, J. M

“…In this study, we have investigated the properties of intermediate filament rearrangements using experimentally induced collapse of vimentin intermediate…”
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p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion by Grosheva, I, Shtutman, M, Elbaum, M, Bershadsky, A D

“…The molecular basis for contact inhibition of cell locomotion is still largely unknown. Cadherins, the major receptors mediating cell-cell adhesion, associate…”
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Cytoskeletal involvement in the modulation of cell-cell junctions by the protein kinase inhibitor H-7 by CITI, S, VOLBERG, T, BERSHADSKY, A. D, DENISENKO, N, GEIGER, B

“…The protein kinase inhibitor H-7 has been shown to block junction dissociation induced by low extracellular calcium in Madin Darby canine kidney epithelial…”
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Evidence that intermediate filament reorganization is induced by ATP-dependent contraction of the actomyosin cortex in permeabilized fibroblasts by TINT, I. S, HOLLENBECK, P. J, VERKHOVSKY, A. B, SURGUCHEVA, I. G, BERSHADSKY, A. D

“…Intermediate filaments (IFs) undergo specific rearrangements in cells, some aspects of which can be induced experimentally. Centripetal aggregation of the IF…”
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Cadherin-mediated regulation of microtubule dynamics by Borisy, Gary G, Chausovsky, Alexander, Bershadsky, Alexander D

“…Epithelial polarization and neuronal outgrowth require the assembly of microtubule arrays that are not associated with centrosomes. As these processes…”
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Microtubule involvement in regulating cell contractility and adhesion-dependent signalling: a possible mechanism for polarization of cell motility by Elbaum, M, Chausovsky, A, Levy, E T, Shtutman, M, Bershadsky, A D

“…The dynamic shape of an isolated cell results from an interplay between protrusion, adhesion and contraction activities. These are most closely associated with…”
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Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions by Helfman, D M, Levy, E T, Berthier, C, Shtutman, M, Riveline, D, Grosheva, I, Lachish-Zalait, A, Elbaum, M, Bershadsky, A D

“…Caldesmon is known to inhibit the ATPase activity of actomyosin in a Ca(2+)-calmodulin-regulated manner. Although a nonmuscle isoform of caldesmon is widely…”
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Cytoskeletal Reorganizations Responsible for the Phorbol Ester-Induced Formation of Cytoplasmic Processes: Possible Involvement of Intermediate Filaments by Bershadsky, A. D., Ivanova, O. Y., Lyass, L. A., Pletyushkina, O. Y., Vasiliev, J. M., Gelfand, I. M.

“…The tumor promoter phorbol 12-myristate 13-acetate (PMA) induces characteristic reversible changes of cell shape in certain fibroblastic lines: motile lamellas…”
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Post-Translational Modification of Microtubules is a Component of Synergic Alterations of Cytoskeleton Leading to Formation of Cytoplasmic Processes in Fibroblasts by Tint, I. S., Bershadsky, A. D., Gelfand, I. M., Vasiliev, J. M.

“…The protein kinase C activator phorbol 12-myristate 13-acetate (PMA) induces rapid and reversible shape changes in cultured fibroblasts: extension of motile…”
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Actin cytoskeleton of spread fibroblasts appears to assemble at the cell edges by Svitkina, T.M, Neyfakh, A.A. Jr, Bershadsky, A.D

“…The action of metabolic inhibitors on actin cytoskeleton of cultured quail embryo fibroblasts has been studied using electron microscopy of platinum replicas…”
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ATP-Dependent Regulation of Cytoplasmic Microtubule Disassembly by Bershadsky, A. D., Gelfand, V. I.

“…Indirect immunofluorescent staining with an antitubulin antibody was used for studying the role of ATP in the regulation of cytoplasmic microtubule…”
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Stimulation of actin synthesis in phalloidin-treated cells: Evidence for autoregulatory control by Serpinskaya, A.S., Denisenko, O.N., Gelfand, V.I., Bershadsky, A.D.

“…We used the technique of scrape loading to introduce phalloidin into mouse embryo fibroblasts in mass culture. Phalloidin almost completely destroyed actin…”
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Microtubule-Dependent Effect of Phorbol Ester on the Contractility of Cytoskeleton of Cultured Fibroblasts by Lyass, L. A., Bershadsky, A. D., Vasiliev, J. M., Gelfand, I. M.

“…The effect of the tumor promoter phorbol 12-myristate 13-acetate (PMA) upon the contractility of permeabilized cell models (cytoskeletons) of mouse fibroblasts…”
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Focal contacts of normal and RSV-transformed quail cells. Hypothesis of the transformation-induced deficient maturation of focal contacts by Bershadsky, A D, Tint, I S, Neyfakh, Jr, A A, Vasiliev, J M

“…Morphology and distribution of cell-substrate contacts and their association with microfilament bundles in normal and RSV-transformed quail fibroblasts (16Q…”
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