Search Results - "Berry, Jesse L."
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Characterizing DNA methylation signatures of retinoblastoma using aqueous humor liquid biopsy
Published in Nature communications (21-09-2022)“…Retinoblastoma (RB) is a cancer that forms in the developing retina of babies and toddlers. The goal of therapy is to cure the tumor, save the eye and maximize…”
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Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival
Published in Molecular cancer research (01-08-2020)“…Aqueous humor contains tumor-derived cell-free DNA (cfDNA) and can serve as a liquid biopsy for retinoblastoma. We previously associated somatic copy-number…”
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Comparative Single Vesicle Analysis of Aqueous Humor Extracellular Vesicles before and after Radiation in Uveal Melanoma Eyes
Published in International journal of molecular sciences (01-06-2024)“…Small extracellular vesicles (sEVs) have been shown to promote tumorigenesis, treatment resistance, and metastasis in multiple cancer types; however, sEVs in…”
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Conjunctival Squamous Neoplasia: Staging and Initial Treatment
Published in Cornea (01-10-2018)“…PURPOSE:To evaluate the clinical relevance of the American Joint Committee on Cancer (AJCC) classification in the initial management of squamous neoplasia of…”
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Simultaneous Copy Number Alteration and Single-Nucleotide Variation Analysis in Matched Aqueous Humor and Tumor Samples in Children with Retinoblastoma
Published in International journal of molecular sciences (11-05-2023)“…Retinoblastoma (RB) is a childhood cancer that forms in the developing retina of young children; this tumor cannot be biopsied due to the risk of provoking…”
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Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma
Published in International journal of molecular sciences (01-04-2023)“…Gene expression profiling (GEP) is clinically validated to stratify the risk of metastasis by assigning uveal melanoma (UM) patients to two highly prognostic…”
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Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors
Published in NPJ precision oncology (20-02-2023)“…We designed a liquid biopsy (LB) platform employing low-pass whole genome sequencing (LP-WGS) and targeted sequencing of cell-free (cf) DNA from plasma to…”
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Anterior plaque brachytherapy placement for treatment of iris and iridociliary melanomas - Surgical procedure and institutional experience
Published in Indian journal of ophthalmology (01-06-2024)“…Surgical placement of eye plaque brachytherapy (EPB) is the standard of care for the treatment of uveal melanomas, including iris/iridociliary melanomas…”
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Potential of Aqueous Humor as a Liquid Biopsy for Uveal Melanoma
Published in International journal of molecular sciences (02-06-2022)“…Tumor biopsy can identify prognostic biomarkers for metastatic uveal melanoma (UM), however aqueous humor (AH) liquid biopsy may serve as an adjunct. This…”
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The RB1 Story: Characterization and Cloning of the First Tumor Suppressor Gene
Published in Genes (01-11-2019)“…The gene is the first described human tumor suppressor gene and plays an integral role in the development of retinoblastoma, a pediatric malignancy of the eye…”
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Aqueous Humor Is Superior to Blood as a Liquid Biopsy for Retinoblastoma
Published in Ophthalmology (Rochester, Minn.) (01-04-2020)Get full text
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Cytomegalovirus Retinitis in an Eye with Unilateral Retinoblastoma: A Case Report
Published in Case reports in ophthalmology (01-01-2024)“…Abstract Introduction: Cytomegalovirus (CMV) retinitis in the setting of pediatric retinoblastoma is exceedingly unusual. Here, we present the first reported…”
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Lag Time between Onset of First Symptom and Treatment of Retinoblastoma: An International Collaborative Study of 692 Patients from 10 Countries
Published in Cancers (19-04-2021)“…The relationship between lag time and outcomes in retinoblastoma (RB) is unclear. In this study, we aimed to study the effect of lag time between onset of…”
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Intraocular Spread of Ocular Surface Squamous Neoplasia Presenting as a Postoperative Anterior Chamber Opacity after Excisional Biopsy
Published in Case reports in ophthalmology (01-01-2023)“…Abstract We describe a rare case of ocular surface squamous neoplasia (OSSN) with intraocular spread after excisional biopsy which presented as a postoperative…”
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Intravitreal Melphalan for Retinoblastoma: The Impact of Toxicity on Recurrence and Ultimate Globe Salvage
Published in Ocular oncology and pathology (01-12-2020)“…Introduction: Intravitreal melphalan (IVM) has emerged as an efficacious treatment for vitreous seeding in retinoblastoma. Although rarely severe, IVM-related…”
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Integrated Treatment during the Intravitreal Melphalan Era: Concurrent Intravitreal Melphalan and Systemic Chemoreduction
Published in Ocular oncology and pathology (01-11-2018)“…Background: Intravitreal injection of melphalan (IVM) is safe and effective for the treatment of seeding in retinoblastoma. Current protocols require weekly…”
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Metastatic neuroendocrine tumors mimicking as primary ocular disease
Published in American journal of ophthalmology case reports (01-06-2022)“…To report two cases of metastatic neuroendocrine tumors masquerading as primary ocular disease. Case 1 is a 38-year-old man who was referred with subacute…”
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Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy
Published in NPJ precision oncology (27-07-2021)“…Germline alterations in the RB1 tumor suppressor gene predispose patients to develop retinoblastoma (RB) in both eyes. While similar treatment is given for…”
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An Intraocular Pressure Predictive of High-risk Histopathologic Features in Group E Retinoblastoma Eyes
Published in International ophthalmology clinics (01-01-2019)Get full text
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Rare Tumors: Opportunities and challenges from the Children’s Oncology Group perspective
Published in EJC paediatric oncology (01-12-2023)“…While all childhood cancers are rare, tumors that are particularly infrequent or underrepresented within pediatrics are studied under the umbrella of the…”
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