Search Results - "Berry, Fred B."

Pleiotropy in FOXC1-attributable phenotypes involves altered ciliation and cilia-dependent signaling by Havrylov, Serhiy, Chrystal, Paul, van Baarle, Suey, French, Curtis R., MacDonald, Ian M., Avasarala, Jagannadha, Rogers, R. Curtis, Berry, Fred B., Kume, Tsutomu, Waskiewicz, Andrew J., Lehmann, Ordan J.

“…Alterations to cilia are responsible for a wide range of severe disease; however, understanding of the transcriptional control of ciliogenesis remains…”
Get full text

Initiation of early osteoblast differentiation events through the direct transcriptional regulation of Msx2 by FOXC1 by Mirzayans, Farideh, Lavy, Rotem, Penner-Chea, Jonathan, Berry, Fred B

“…Hierarchal transcriptional regulatory networks function to control the correct spatiotemporal patterning of the mammalian skeletal system. One such factor, the…”
Get full text

Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies by Asai-Coakwell, Mika, March, Lindsey, Dai, Xiao Hua, Duval, Michele, Lopez, Irma, French, Curtis R, Famulski, Jakub, De Baere, Elfride, Francis, Peter J, Sundaresan, Periasamy, Sauvé, Yves, Koenekoop, Robert K, Berry, Fred B, Allison, W Ted, Waskiewicz, Andrew J, Lehmann, Ordan J

“…Retinal dystrophies are predominantly caused by mutations affecting the visual phototransduction system and cilia, with few genes identified that function to…”
Get full text

FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A by Berry, Fred B., Skarie, Jonathan M., Mirzayans, Farideh, Fortin, Yannick, Hudson, Thomas J., Raymond, Vincent, Link, Brian A., Walter, Michael A.

“…Mutations in the human FOXC1 transcription factor gene underlie Axenfeld–Rieger (AR) syndrome, a disorder characterized by anterior segment malformations in…”
Get full text

Regulation of FOXC1 Stability and Transcriptional Activity by an Epidermal Growth Factor-activated Mitogen-activated Protein Kinase Signaling Cascade by Berry, Fred B., Mirzayans, Farideh, Walter, Michael A.

“…Mutations in the FOXC1 transcription factor gene result in Axenfeld Rieger malformations, a disorder that affects the anterior segment of the eye, the teeth,…”
Get full text

Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification by Almubarak, Asra, Lavy, Rotem, Srnic, Nikola, Hu, Yawen, Maripuri, Devi Priyanka, Kume, Tsutomo, Berry, Fred B.

“…Endochondral ossification initiates the growth of the majority of the mammalian skeleton and is tightly controlled through gene regulatory networks. The…”
Get full text

FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton by Almubarak, Asra, Zhang, Qiuwan, Zhang, Cheng-Hai, Abdelwahab, Noor, Kume, Tsutomu, Lassar, Andrew B, Berry, Fred B

“…The Forkhead box transcription factors FOXC1 and FOXC2 are expressed in condensing mesenchyme cells at the onset of endochondral ossification. We used the…”
Get more information

FOXC1 Regulates FGFR1 Isoform Switching to Promote Invasion Following TGFβ-Induced EMT by Hopkins, Alex, Coatham, Mackenzie L, Berry, Fred B

“…Epithelial-to-mesenchymal transition (EMT) is an important physiologic process that drives tissue formation during development, but also contributes to disease…”
Get full text

FOXC1 Transcriptional Regulatory Activity Is Impaired by PBX1 in a Filamin A-Mediated Manner by Berry, Fred B., O'Neill, Megan A., Coca-Prados, Miguel, Walter, Michael A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

FOXC1 negatively regulates BMP‐SMAD activity and Id1 expression during osteoblast differentiation by Caddy, Jordan C., Luoma, Leiah M., Berry, Fred B.

“…Bone morphogenetic proteins regulate a diverse range of biological processes through their activation of SMAD1, SMAD5, or SMAD8 proteins that, in turn,…”
Get full text

FGF19 is a target for FOXC1 regulation in ciliary body-derived cells by Tamimi, Yahya, Skarie, Jonathan M., Footz, Tim, Berry, Fred B., Link, Brian A., Walter, Michael A.

“…The forkhead C1 (FOXC1) transcription factor is involved in the development and regulation of several organs, including the eye, where FOXC1 alterations cause…”
Get full text

FOXC1 Transcriptional Regulation Is Mediated by N- and C-terminal Activation Domains and Contains a Phosphorylated Transcriptional Inhibitory Domain by Berry, Fred B., Saleem, Ramsey A., Walter, Michael A.

“…Mutations in the FOXC1 gene result in Axenfeld-Rieger malformations of the anterior segment of the eye and lead to an increased susceptibility of glaucoma. To…”
Get full text

Molecular analysis of NPAS3 functional domains and variants by Luoma, Leiah M, Berry, Fred B

“…NPAS3 encodes a transcription factor which has been associated with multiple human psychiatric and neurodevelopmental disorders. In mice, deletion of Npas3 was…”
Get full text

Muscle dysfunction caused by loss of Magel2 in a mouse model of Prader-Willi and Schaaf-Yang syndromes by Kamaludin, Ain A, Smolarchuk, Christa, Bischof, Jocelyn M, Eggert, Rachelle, Greer, John J, Ren, Jun, Lee, Joshua J, Yokota, Toshifumi, Berry, Fred B, Wevrick, Rachel

“…Prader-Willi syndrome is characterized by severe hypotonia in infancy, with decreased lean mass and increased fat mass in childhood followed by severe…”
Get full text

A Novel Locus Predicts Spermatogenic Recovery among Childhood Cancer Survivors Exposed to Alkylating Agents by Sapkota, Yadav, Wilson, Carmen L, Zaidi, Asifa K, Moon, Wonjong, Fon Tacer, Klementina, Lu, Lu, Liu, Qi, Baedke, Jessica, Dhaduk, Rikeenkumar, Wang, Zhaoming, Chemaitilly, Wassim, Krasin, Matthew J, Berry, Fred B, Zhang, Jinghui, Hudson, Melissa M, Robison, Leslie L, Green, Daniel M, Yasui, Yutaka

“…Exposure to high doses of alkylating agents is associated with increased risk of impaired spermatogenesis among nonirradiated male survivors of childhood…”
Get full text

Severe Molecular Defects of a Novel FOXC1 W152G Mutation Result in Aniridia by Ito, Yoko A, Footz, Tim K, Berry, Fred B, Mirzayans, Farideh, Yu, May, Khan, Arif O, Walter, Michael A

“…FOXC1 mutations result in Axenfeld-Rieger syndrome, a disorder characterized by a broad spectrum of malformations of the anterior segment of the eye and an…”
Get full text

Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld–Rieger syndrome and anterior segment dysgenesis by Berry, Fred B., Lines, Matthew A., Oas, J. Martin, Footz, Tim, Underhill, D. Alan, Gage, Philip J., Walter, Michael A.

“…Axenfeld–Rieger ocular dysgenesis is associated with mutations of the human PITX2 and FOXC1 genes, which encode transcription factors of the homeodomain and…”
Get full text

PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3 by Strungaru, M Hermina, Footz, Tim, Liu, Yi, Berry, Fred B, Belleau, Pascal, Semina, Elena V, Raymond, Vincent, Walter, Michael A

“…Mutations of the PITX2 gene cause Axenfeld-Rieger syndrome (ARS) and glaucoma. In this study, the authors investigated genes directly regulated by the PITX2…”
Get full text

Human p32 Is a Novel FOXC1-Interacting Protein That Regulates FOXC1 Transcriptional Activity in Ocular Cells by Huang, LiJia, Chi, Jonathan, Berry, Fred B, Footz, Timothy K, Sharp, Michael W, Walter, Michael A

“…Mutations in the human forkhead box C1 gene (FOXC1) cause Axenfeld-Rieger (AR) malformations, often leading to glaucoma. Understanding the function of FOXC1…”
Get full text

Structural and functional analyses of disease-causing missense mutations in the forkhead domain of FOXC1 by Saleem, Ramsey A., Banerjee-Basu, Sharmila, Berry, Fred B., Baxevanis, Andreas D., Walter, Michael A.

“…Five missense mutations (P79L, P79T, I91S, I91T and R127H) within the forkhead DNA-binding domain of the FOXC1 transcription factor, identified in patients…”
Get full text