Search Results - "Berrettini, W. H."

The CHRNA5–A3–B4 gene cluster in nicotine addiction by Berrettini, W H, Doyle, G A

“…Nicotine addiction (NA) is a common and devastating disease, such that the annual number of deaths (world-wide) from tobacco-related diseases will double from…”
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The Genetics of Anorexia Nervosa by Clarke, T K, Weiss, A R D, Berrettini, W H

“…Anorexia nervosa (AN) is a disease defined by inappropriate weight loss and maintenance of body weight <85% of that expected for weight and height; it is most…”
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Association of OPRM1 A118G variant with the relative reinforcing value of nicotine by RAY, R, JEPSON, C, PATTERSON, F, STRASSER, A, RUKSTALIS, M, PERKINS, K, LYNCH, K. G, O'MALLEY, S, BERRETTINI, W. H, LERMAN, C

“…The endogenous opioid system has been implicated in substance abuse and response to pharmacotherapies for nicotine and alcohol addiction. We examined (1) the…”
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Case–control association analysis of polymorphisms in the delta-opioid receptor, OPRD1 , with cocaine and opioid addicted populations by Crist, R.C, Ambrose-Lanci, L.M, Vaswani, M, Clarke, T.K, Zeng, A, Yuan, C, Ferraro, T.N, Hakonarson, H, Kampman, K.M, Dackis, C.A, Pettinati, H.M, O’Brien, C.P, Oslin, D.W, Doyle, G.A, Lohoff, F.W, Berrettini, W.H

“…Abstract Background Addiction susceptibility and treatment responsiveness are greatly influenced by genetic factors. Sequence variation in genes involved in…”
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Evidence for a Susceptibility Gene for Anorexia Nervosa on Chromosome 1 by Grice, D.E., Halmi, K.A., Fichter, M.M., Strober, M., Woodside, D.B., Treasure, J.T., Kaplan, A.S., Magistretti, P.J., Goldman, D., Bulik, C.M., Kaye, W.H., Berrettini, W.H.

“…Eating disorders, such as anorexia nervosa (AN), have a significant genetic component. In the current study, a genomewide linkage analysis of 192 families with…”
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The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial by Lerman, C, Wileyto, E P, Patterson, F, Rukstalis, M, Audrain-McGovern, J, Restine, S, Shields, P G, Kaufmann, V, Redden, D, Benowitz, N, Berrettini, W H

“…To determine whether the functional mu-opioid receptor (OPRM1) Asn40Asp variant predicts the comparative efficacy of different forms of NRT, we conducted a…”
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Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction by Clarke, T.‐K., Ambrose‐Lanci, L., Ferraro, T. N., Berrettini, W. H., Kampman, K. M., Dackis, C. A., Pettinati, H. M., O’Brien, C. P., Oslin, D. W., Lohoff, F. W.

“…Genetic factors are believed to account for 30–50% of the risk for cocaine and heroin addiction. Dynorphin peptides, derived from the prodynorphin (PDYN)…”
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Anorexia nervosa trios: behavioral profiles of individuals with anorexia nervosa and their parents by Jacobs, M J, Roesch, S, Wonderlich, S A, Crosby, R, Thornton, L, Wilfley, D E, Berrettini, W H, Brandt, H, Crawford, S, Fichter, M M, Halmi, K A, Johnson, C, Kaplan, A S, Lavia, M, Mitchell, J E, Rotondo, A, Strober, M, Woodside, D B, Kaye, W H, Bulik, C M

“…Anorexia nervosa (AN) is associated with behavioral traits that predate the onset of AN and persist after recovery. We identified patterns of behavioral traits…”
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Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons by Reyes, B.A.S., Vakharia, K., Ferraro, T.N., Levenson, R., Berrettini, W.H., Van Bockstaele, E.J.

“…Wntless (WLS), a mu-opioid receptor (MOR) interacting protein, mediates Wnt protein secretion that is critical for neuronal development. We investigated…”
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Susceptibility loci for bipolar disorder: overlap with inherited vulnerability to schizophrenia by Berrettini, Wade H

“…Genetic epidemiological studies reveal that relatives of bipolar probands are at increased risk for recurrent unipolar, bipolar, and schizoaffective disorders,…”
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Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility by Buono, R.J, Lohoff, F.W, Sander, T, Sperling, M.R, O’Connor, M.J, Dlugos, D.J, Ryan, S.G, Golden, G.T, Zhao, H, Scattergood, T.M, Berrettini, W.H, Ferraro, T.N

“…Purpose: Our research program uses genetic linkage and association analysis to identify human seizure sensitivity and resistance alleles. Quantitative trait…”
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Confirmation of association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and bipolar I disorder by Lohoff, F.W., Sander, T., Ferraro, T.N., Dahl, J.P., Gallinat, J., Berrettini, W.H.

“…Recent studies have indicated that the brain‐derived neurotrophic factor (BDNF) gene is involved in the etiology of bipolar disorder (BPD). Two family‐based…”
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Are schizophrenic and bipolar disorders related? A review of family and molecular studies by Berrettini, Wade H

“…Schizophrenic and bipolar disorders are similar in several epidemiologic respects, including age at onset, lifetime risk, course of illness, worldwide…”
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Candidate genes for anorexia nervosa in the 1p33-36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa by BERGEN, A. W, VAN DEN BREE, M. B. M, BULIK, C. M, KLUMP, K, FICHTER, M, HALMI, K, KAPLAN, A, STROBER, M, TREASURE, J, WOODSIDE, B, KAYE, W. H, YEAGER, M, WELCH, R, GANJEI, J. K, HAQUE, K, BACANU, S, BERRETTINI, W. H, GRICE, D. E, GOLDMAN, D

“…Serotonergic and opioidergic neurotransmitter system alterations have been observed in people with eating disorders; the genes for the serotonin 1D receptor…”
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Alternative transcripts and evidence of imprinting of GNAL on 18p11.2 by CORRADI, J. P, RAVYN, V, ROBBINS, A. K, HAGAN, K. W, PETERS, M. F, BOSTWICK, R, BUONO, R. J, BERRETTINI, W. H, FURLONG, S. T

“…Genetic studies implicating the region of human chromosome 18p11.2 in susceptibility to bipolar disorder and schizophrenia have observed parent-of-origin…”
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Perfectionism in Anorexia Nervosa: Variation by Clinical Subtype, Obsessionality, and Pathological Eating Behavior by Halmi, Katherine A., Sunday, Suzanne R., Strober, Michael, Kaplan, Alan, Woodside, D. Blake, Fichter, Manfred, Treasure, Janet, Berrettini, Wade H., Kaye, Walter H.

“…OBJECTIVE: The purpose of this study was to examine the role of perfectionism as a phenotypic trait in anorexia nervosa and its relevance across clinical…”
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Confirmation of multiple seizure susceptibility QTLs on chromosome 15 in C57BL/6J and DBA/2J inbred mice by Ferraro, T N, Smith, G G, Schwebel, C L, Doyle, G A, Ruiz, S E, Oleynick, J U, Lohoff, F W, Berrettini, W H, Buono, R J

“…To confirm seizure susceptibility (SZS) quantitative trait loci (QTLs) on chromosome (chr) 15 identified previously using C57BL/6J (B6) and DBA/2J (D2) mice…”
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Genetics of Psychiatric Disease by Berrettini, Wade H

“…Genetic epidemiologic studies reveal that relatives of bipolar (BIP) probands are at increased risk for recurrent unipolar (RUP), BIP, and schizoaffective (SA)…”
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Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants by Gamazon, E R, Badner, J A, Cheng, L, Zhang, C, Zhang, D, Cox, N J, Gershon, E S, Kelsoe, J R, Greenwood, T A, Nievergelt, C M, Chen, C, McKinney, R, Shilling, P D, Schork, N J, Smith, E N, Bloss, C S, Nurnberger, J I, Edenberg, H J, Foroud, T, Koller, D L, Scheftner, W A, Coryell, W, Rice, J, Lawson, W B, Nwulia, E A, Hipolito, M, Byerley, W, McMahon, F J, Schulze, T G, Berrettini, W H, Potash, J B, Zandi, P P, Mahon, P B, McInnis, M G, Zöllner, S, Zhang, P, Craig, D W, Szelinger, S, Barrett, T B, Liu, C

“…We conducted a systematic study of top susceptibility variants from a genome-wide association (GWA) study of bipolar disorder to gain insight into the…”
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A polymorphism in the OPRM1 3′-untranslated region is associated with methadone efficacy in treating opioid dependence by Crist, R C, Doyle, G A, Nelson, E C, Degenhardt, L, Martin, N G, Montgomery, G W, Saxon, A J, Ling, W, Berrettini, W H

“…The μ-opioid receptor (MOR) is the primary target of methadone and buprenorphine. The primary neuronal transcript of the OPRM1 gene, MOR-1, contains a ~13 kb…”
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