Search Results - "Bernstein, Joel M."

Further observations on the role of Staphylococcus aureus exotoxins and IgE in the pathogenesis of nasal polyposis by Bernstein, Joel M., Allen, Cheryl, Rich, Gary, Dryja, Diane, Bina, Paul, Reiser, Raoul, Ballow, Mark, Wilding, Gregory E.

“…Objectives/Hypothesis: Recent studies have suggested that Staphylococcus aureus secrete exotoxins that may act as superantigens and upregulate the variable…”
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Exosomes Represent an Immune Suppressive T Cell Checkpoint in Human Chronic Inflammatory Microenvironments by Shenoy, Gautam N, Bhatta, Maulasri, Loyall, Jenni L, Kelleher Jr, Raymond J, Bernstein, Joel M, Bankert, Richard B

“…Background: T cells present in chronic inflammatory tissues such as nasal polyps (from chronic rhinosinusitis patients) have been demonstrated to be…”
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Genetic polymorphisms in chronic hyperplastic sinusitis with nasal polyposis by Bernstein, Joel M., Anon, Jack B., Rontal, Michael, Conroy, Jeffrey, Wang, Chong, Sucheston, Lara

“…Objectives/Hypothesis: Although many proinflammatory cytokines have been identified in nasal polyp tissue, the initial trigger that causes this inflammation…”
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Immunologic Diseases of the Ear

“…Otitis media (OM) is an inflammation of the middle ear which may lead to the destruction of middle- and inner-ear structures. This can result in severe hearing…”
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Superantigen hypothesis for the early development of chronic hyperplastic sinusitis with massive nasal polyposis by Bernstein, Joel M, Kansal, Rita

“…The pathogenesis, pathophysiology, and immunobiology of chronic hyperplastic sinusitis with massive nasal polyposis are starting to become unraveled. Allergy,…”
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Bacteria-mucin interaction in the upper aerodigestive tract shows striking heterogeneity: Implications in otitis media, rhinosinusitis, and pneumonia by BERNSTEIN, JOEL M., REDDY, MOLAKALA

“…The mucociliary system of the upper and lower respiratory tracts is a critical nonspecific pathway for the elimination of bacteria and other particulate…”
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Update on the molecular biology of nasal polyposis by Bernstein, Joel M

“…The definition of CRS with and without nasal polyposis continues to evolve. It may require an understanding of a broader range of etiologies and pathogenesis…”
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Humanized Mouse Model Used to Monitor MUC Gene Expression in Nasal Polyps and to Preclinically Evaluate the Efficacy of Montelukast in Reducing Mucus Production by Bernstein, Joel M., Lehman, Heather, Lis, Maciej, Sands, Amy, Wilding, Gregory E., Shultz, Leonard, Bankert, Richard, Bobek, Libuse

“…Objectives: To determine whether MUC gene expression could be down-regulated in nasal polyps by the leukotriene receptor antagonist montelukast, we developed a…”
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Bacterial interference in upper respiratory tract infections: a systematic review by Benninger, Michael, Brook, Itzhak, Bernstein, Joel M, Casey, Janet R, Roos, Kristian, Marple, Bradley, Farrar, Judith R

“…Published definitions of bacterial interference (BI) differ, some focusing on changes in the normal flora and others on changes in subsequent infection. A need…”
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The molecular biology of nasal polyposis by Bernstein, J M

“…The molecular biologic events in the development of nasal polyps are now becoming unraveled. It appears that eosinophils are the dominant inflammatory cell…”
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Lymphocyte subpopulations and cytokines in nasal polyps: is there a local immune system in the nasal polyp? by Bernstein, Joel M, Ballow, Mark, Rich, Gary, Allen, Cheryl, Swanson, Mia, Dmochowski, Jacek

“…The pathogenesis of chronic hyperplastic rhinosinusitis with massive nasal polyposis is still not entirely known. The present study evaluates the lymphocyte…”
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IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells by Broderick, Lori, Brooks, Stephen P., Takita, Hiroshi, Baer, Alan N., Bernstein, Joel M., Bankert, Richard B.

“…Memory T cells in human non-small cell lung cancer are unresponsive to progressing tumors. T cells were evaluated at the single cell level by imaging the…”
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Memory T Cells in the Chronic Inflammatory Microenvironment of Nasal Polyposis are Hyporesponsive to Signaling Through the T Cell Receptor by Lehman, Heather K., Simpson-Abelson, Michelle R., Conway, Thomas F., Kelleher, Raymond J., Bernstein, Joel M., Bankert, Richard B.

“…A majority of T cells from chronic inflammatory tissues derived from patients with nasal polyposis were found to express an effector memory phenotype. We…”
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Molecular analysis of bacterial flora associated with chronically inflamed maxillary sinuses by Paju, Susanna, Bernstein, Joel M, Haase, Elaine M, Scannapieco, Frank A

“…Department of Oral Biology, School of Dental Medicine 1 and Department of Otolaryngology, School of Medicine and Biomedical Sciences 2 , State University of…”
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Immunologic aspects of otitis media by Bernstein, Joel M

“…The middle ear cleft is a modified gas pocket which functions normally when the gas contents are regulated by a normal eustachian tube, resulting in…”
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Human Nasal Polyp Microenvironments Maintained in a Viable and Functional State as Xenografts in NOD-scid IL2rγnull Mice by Bernstein, Joel M., Brooks, Stephen P., Lehman, Heather K., Pope, Liza, Sands, Amy, Shultz, Leonard D., Bankert, Richard B.

“…Objectives: The objective was to develop a model with which to study the cellular and molecular events associated with nasal polyp progression. To accomplish…”
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Bacterial Interference of Penicillin-Sensitive and -Resistant Streptococcus Pneumoniae by Streptococcus Oralis in an Adenoid Organ Culture: Implications for the Treatment of Recurrent Upper Respiratory Tract Infections in Children and Adults by Bernstein, Joel M., Hasse, Elaine, Scannapieco, Frank, Dryja, Diane, Wolf, Judy, Briles, David, King, Janice, Wilding, Gregory E.

“…Objectives: The role of the viridans group of streptococci (Streptococcus oralis) in the prevention of colonization with Streptococcus pneumoniae was…”
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Geographic variation in allergic fungal rhinosinusitis by Ferguson, B J, Barnes, L, Bernstein, J M, Brown, D, Clark, 3rd, C E, Cook, P R, DeWitt, W S, Graham, S M, Gordon, B, Javer, A R, Krouse, J H, Kuhn, F A, Levine, H L, Manning, S C, Marple, B F, Morgan, A H, Osguthorpe, J D, Skedros, D, Rains, 3rd, B M, Ramadan, H H, Terrell, J E, Yonkers, A J

“…Allergic fungal rhinosinusitis (AFRS) has a worldwide distribution. This survey of 20 otolaryngologic practices throughout the United States confirmed a…”
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Human Nasal Polyp Microenvironment Maintained in Viable and Functional States as Xenografts in SCID Mice by Bernstein, Joel M., Broderick, Lori, Parsons, Robert R., Bankert, Richard B.

“…Objectives: We undertook to maintain human nasal polyp tissue in a viable and functional state in SCID (severe combined immunodeficiency) mice. Methods: Small,…”
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Miniseminar: Rhinitis: From science to practice by Golla, Suman, Bernstein, Joel M, Mabry, Richard L, Gordon, Bruce R, Haydon, Richard C

“…Chronic rhinitis is among the most common medical disorders in both the Western world, and is increasing in prevalence in developing nations. Otolaryngologists…”
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