Search Results - "Berns, Kenneth I"
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Gene Therapy Using Adeno-Associated Virus Vectors
Published in Clinical Microbiology Reviews (01-10-2008)“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Next Generation of Adeno-Associated Virus Vectors for Gene Therapy for Human Liver Diseases
Published in Gastroenterology clinics of North America (01-06-2019)“…Recombinant vectors based on a nonpathogenic parvovirus, the adeno-associated virus (AAV), have taken center stage in the past decade. The safety of AAV…”
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Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma?
Published in Human gene therapy (01-12-2015)Get more information
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Adeno-Associated Virus Site-Specific Integration Is Mediated by Proteins of the Nonhomologous End-Joining Pathway
Published in Journal of Virology (15-11-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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AAV: An Overview of Unanswered Questions
Published in Human gene therapy (01-04-2017)“…AAV has been studied for 55 years and has been developed as a vector for about 35 years. By now, there is a fairly good idea of the dimensions of what would be…”
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Grand challenges for biosafety and biosecurity
Published in Frontiers in bioengineering and biotechnology (2014)Get full text
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Adeno-Associated Virus Type-2 Expression of Pigmented Epithelium-Derived Factor or Kringles 1-3 of Angiostatin Reduce Retinal Neovascularization
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2002)“…Neovascular diseases of the retina include age-related macular degeneration and diabetic retinopathy, and together they comprise the leading causes of…”
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Interleukin 10 Attenuates Neointimal Proliferation and Inflammation in Aortic Allografts by a Heme Oxygenase-Dependent Pathway
Published in Proceedings of the National Academy of Sciences - PNAS (17-05-2005)“…Interleukin 10 (IL-10) is a pleiotropic cytokine with well known antiinflammatory, immunosuppressive, and immunostimulatory properties. Chronic allograft…”
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DNA-Dependent PK Inhibits Adeno-Associated Virus DNA Integration
Published in Proceedings of the National Academy of Sciences - PNAS (17-02-2004)“…Recent studies have shown that recombinant adeno-associated virus (rAAV) can persist in episomal form; however, factors affecting rAAV persistence are poorly…”
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A p5 Integration Efficiency Element Mediates Rep-Dependent Integration into AAVS1 at Chromosome 19
Published in Proceedings of the National Academy of Sciences - PNAS (17-09-2002)“…Adeno-associated virus (AAV) undergoes site-specific integration into human chromosome 19 through a deletion-substitution mechanism at the well characterized…”
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Adeno-Associated Virus Site-Specific Integration and AAVS1 Disruption
Published in Journal of Virology (01-08-2004)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effect of DNA-Dependent Protein Kinase on the Molecular Fate of the rAAV2 Genome in Skeletal Muscle
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2001)“…We report here that the DNA-dependent protein kinase (DNA-PK) affects the molecular fate of the recombinant adeno-associated virus (rAAV) genome in skeletal…”
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Efficient Integration of Recombinant Adeno-Associated Virus DNA Vectors Requires a p5-rep Sequence in cis
Published in Journal of Virology (01-06-2002)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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My life with adeno-associated virus: a long time spent studying a short genome
Published in DNA and cell biology (01-07-2013)“…My 45 years of studying the molecular biology of adeno-associated virus are recounted. Additional activities as a mentor, department chair, and medical school…”
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Characterization of the Mouse Adeno-Associated Virus AAVS1 Ortholog
Published in Journal of Virology (01-08-2004)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Gene delivery in renal tubular epithelial cells using recombinant adeno-associated viral vectors
Published in Journal of the American Society of Nephrology (01-04-2003)“…Gene therapy has the potential to provide a therapeutic strategy for numerous renal diseases such as diabetic nephropathy, chronic rejection, Alport syndrome,…”
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The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG)
Published in Vaccine (01-01-2015)“…Abstract Recombinant viral vectors provide an effective means for heterologous antigen expression in vivo and thus represent promising platforms for developing…”
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Adeno-Associated Virus (AAV) Site-Specific Integration: Formation of AAV-AAVS1 Junctions in an in vitro System
Published in Proceedings of the National Academy of Sciences - PNAS (26-10-1999)“…An in vitro system to study the mechanism of site-specific integration of adeno-associated virus (AAV) was developed. This system is based on two substrates, a…”
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