Search Results - "Bernhard, M.K."

V25. Benign familial neonatal seizures and transient neonatal diabetes in a family with a mutation in ABCC8 encoding the SUR1 subunit of the ATP-sensitive potassium (K-ATP) channel by Syrbe, S, Houghton, J, Bernhard, M.K, Lemke, J, Kapellen, T.M, Merkenschlager, A

“…Introduction Benign familial neonatal seizures (BFNS) are a distinct epilepsy syndrome with selflimited seizures starting in the first days of life. The…”
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Carbamoylation abrogates the antioxidant potential of hydrogen sulfide by Praschberger, Monika, Hermann, Marcela, Laggner, Christian, Jirovetz, Leopold, Exner, Markus, Kapiotis, Stylianos, Gmeiner, Bernhard M.K., Laggner, Hilde

“…Hydrogen sulfide (H2S) has been identified as the third gasotransmitter. Beside its role as signaling molecule in the cardiovascular and nervous system the…”
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Response to Black R and Chin R's letter on our article “Epilepsy in children and adolescents: Disease concepts, practical knowledge, and coping” by Pauschek, J, Bernhard, M.K, Syrbe, S, Nickel, P, Neininger, M.P, Merkenschlager, A, Kiess, W, Bertsche, T, Bertsche, A

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The importance of laboratory re-evaluation in cases of suspected child abuse – A case report by Woydt, L., König, C., Bernhard, M.K., Nickel, P., Dreßler, J., Ondruschka, B.

“…•Physicians needs to be familiar with medical conditions that can simulate maltreatment.•Interdisciplinary teamwork is necessary to match all investigation…”
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S-carbamoylation impairs the oxidant scavenging activity of cysteine: Its possible impact on increased LDL modification in uraemia by Schreier, Sabine M, Steinkellner, Hannes, Jirovetz, Leopold, Hermann, Marcela, Exner, Markus, Gmeiner, Bernhard M.K, Kapiotis, Stylianos, Laggner, Hilde

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Sulfite facilitates LDL lipid oxidation by transition metal ions: A pro-oxidant in wine? by Laggner, Hildegard, Hermann, Marcela, Sturm, Brigitte, Gmeiner, Bernhard M.K., Kapiotis, Stylianos

“…Lipid oxidation in LDL may play a role in atherogenesis. It has been shown that sulfite – a compound in the aqueous fraction of wine – could inhibit free…”
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The dietary soy flavonoid genistein abrogates tissue factor induction in endothelial cells induced by the atherogenic oxidized phospholipid oxPAPC by Holzer, Gregor, Esterbauer, Harald, Kronke, Gerhard, Exner, Markus, Kopp, Christoph W, Leitinger, Norbert, Wagner, Oswald, Gmeiner, Bernhard M.K, Kapiotis, Stylianos

“…Abstract Introduction Tissue factor (TF) plays a pivotal role in the generation of thrombin in atherothrombotic disease. The oxidized phospholipid…”
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Genistein prevents the glucose autoxidation mediated atherogenic modification of low density lipoprotein by Exner, M, Hermann, M, Hofbauer, R, Kapiotis, S, Quehenberger, P, Speiser, W, Held, I, Gmeiner, B M

“…Hyperglycemia has been assumed to be responsible for oxidative stress in diabetes. In this respect, glucose autoxidation and advanced glycation end products…”
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The salicylate metabolite gentisic acid, but not the parent drug, inhibits glucose autoxidation-mediated atherogenic modification of low density lipoprotein by Exner, Markus, Hermann, Marcela, Hofbauer, Roland, Kapiotis, Stylianos, Speiser, Wolfgang, Held, Irmtraud, Seelos, Christian, Gmeiner, Bernhard M.K

“…Oxidation of low density lipoprotein (LDL) by glucose-derived radicals may play a role in the aetiology of atherosclerosis in diabetes. Salicylate was shown to…”
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Hydrogen sulphide induces HIF-1α and Nrf2 in THP-1 macrophages by Lohninger, Lilian, Tomasova, Lenka, Praschberger, Monika, Hintersteininger, Michael, Erker, Thomas, Gmeiner, Bernhard M.K., Laggner, Hilde

“…The transcription factor HIF-1α regulates the adaptive response of cells to hypoxia and oxidative stress. In addition, an important regulatory role for HIF-1α…”
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Investigating the role of H₂S in 4-HNE scavenging by Laggner, Hilde, Gmeiner, Bernhard M K

“…4-HNE (4-hydroxy-2-nonenal) is a highly reactive α,β-unsaturated aldehyde generated from oxidation of polyunsaturated fatty acids and has been suggested to…”
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P46 - The uremic toxin indoxyl sulfate acts as a pro- or antioxidant on LDL oxidation by Praschberger, Monika, Hermann, Marcela, Wanner, Juergen, Jirovetz, Leo, Exner, Markus, Kapiotis, Stylianos, Gmeiner, Bernhard M.K., Laggner, Hilde

“…Uremic toxins have been shown to play a role in chronic kidney disease (CKD) associated oxidative stress. Oxidative stress and inflammation have been…”
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How do parents perceive adverse drug events of their children's anticonvulsant medication? by Bach, V.A., Neininger, M.P., Spindler, U.P., Hotopp, L.C., Hornemann, F., Syrbe, S., Merkenschlager, A., Kiess, W., Bernhard, M.K., Bertsche, T., Bertsche, A.

“…The main source of knowledge on adverse drug events (ADE) are physicians' reports in controlled clinical trials. In contrast, little is known about the…”
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The uremic toxin indoxyl sulfate acts as a pro- or antioxidant on LDL oxidation by Praschberger, Monika, Hermann, Marcela, Wanner, Juergen, Jirovetz, Leo, Exner, Markus, Kapiotis, Stylianos, Gmeiner, Bernhard M K, Laggner, Hilde

“…Uremic toxins have been shown to play a role in chronic kidney disease (CKD) associated oxidative stress. Oxidative stress and inflammation have been…”
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Hydrogen sulfide destroys lipid hydroperoxides in oxidized LDL by Muellner, Markus K, Schreier, Sabine M, Laggner, Hilde, Hermann, Marcela, Esterbauer, Harald, Exner, Markus, Gmeiner, Bernhard M K, Kapiotis, Stylianos

“…LOOHs (lipid hydroperoxides) in oxLDL [oxidized LDL (low-density lipoprotein)] are potentially atherogenic compounds. Recently, H2S was identified as the third…”
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Hydrogen sulphide: a novel physiological inhibitor of LDL atherogenic modification by HOCl by Laggner, Hilde, Muellner, Markus K, Schreier, Sabine, Sturm, Brigitte, Hermann, Marcela, Exner, Markus, Gmeiner, Bernhard M K, Kapiotis, Stylianos

“…Hypochlorite (HOCl), the product of the activated myeloperoxidase/H(2)O(2)/chloride (MPO/H(2)O(2)/Cl(- )) system is favored as a trigger of LDL modifications,…”
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Carbamoylated free amino acids in uremia: HOCl generates volatile protein modifying and cytotoxic oxidant species from N-carbamoyl-threonine but not threonine by Schreier, Sabine M., Hollaus, Marianne, Hermann, Marcela, Jirovetz, Leopold, Exner, Markus, Kapiotis, Stylianos, Gmeiner, Bernhard M.K., Laggner, Hilde

“…N-carbamoylation is the non-enzymatic reaction of cyanate with amino groups. Due to urea-formed cyanate in uremic patients beside carbamoylated proteins also…”
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S-Carbamoylation impairs the oxidant scavenging activity of cysteine: Its possible impact on increased LDL modification in uraemia by Schreier, Sabine M., Steinkellner, Hannes, Jirovetz, Leopold, Hermann, Marcela, Exner, Markus, Gmeiner, Bernhard M.K., Kapiotis, Stylianos, Laggner, Hilde

“…Carbamoylation is the non-enzymatic reaction of cyanate with amino-, hydroxy- or thiol groups. In vivo, amino group modification (N-carbamoylation) resulting…”
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The novel gaseous vasorelaxant hydrogen sulfide inhibits angiotensin-converting enzyme activity of endothelial cells by LAGGNER, Hilde, HERMANN, Marcela, ESTERBAUER, Harald, MUELLNER, Markus K, EXNER, Markus, GMEINER, Bernhard M. K, KAPIOTIS, Stylianos

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Effectiveness of bevacizumab for radiation-induced cerebral necrosis in children by Preuss, M, Hirsch, W, Hoffmann, K T, Bernhard, M K, Siekmeyer, M, Kiess, W, Meixensberger, J, Wurm, R E, Merkenschlager, A

“…Bevacizumab has been reported to effectively reduce cerebral edema caused by radiation therapy. However, only limited data with a short follow-up in tumor…”
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