Search Results - "Bernhard, Felix"

Insulin-Like Growth Factor 1 (IGF-1) in Parkinson's Disease: Potential as Trait-, Progression- and Prediction Marker and Confounding Factors by Bernhard, Felix P, Heinzel, Sebastian, Binder, Gerhard, Weber, Karin, Apel, Anja, Roeben, Benjamin, Deuschle, Christian, Maechtel, Mirjam, Heger, Tanja, Nussbaum, Susanne, Gasser, Thomas, Maetzler, Walter, Berg, Daniela

“…Biomarkers indicating trait, progression and prediction of pathology and symptoms in Parkinson's disease (PD) often lack specificity or reliability…”
Get full text

A novel KCNC3 gene variant in the voltage-dependent Kv3.3 channel in an atypical form of SCA13 with dominant central vertigo by Bernhard, Felix P, Schütte, Sven, Heidenblut, Moritz, Oehme, Moritz, Rinné, Susanne, Decher, Niels

“…Potassium channel mutations play an important role in neurological diseases, such as spinocerebellar ataxia (SCA). SCA is a heterogeneous autosomal-dominant…”
Get full text

Wearables for gait and balance assessment in the neurological ward - study design and first results of a prospective cross-sectional feasibility study with 384 inpatients by Bernhard, Felix P, Sartor, Jennifer, Bettecken, Kristina, Hobert, Markus A, Arnold, Carina, Weber, Yvonne G, Poli, Sven, Margraf, Nils G, Schlenstedt, Christian, Hansen, Clint, Maetzler, Walter

“…Deficits in gait and balance are common among neurological inpatients. Currently, assessment of these patients is mainly subjective. New assessment options…”
Get full text

Saccade, Pupil, and Blink Responses in Rapid Eye Movement Sleep Behavior Disorder by Perkins, Julia E., Janzen, Annette, Bernhard, Felix P., Wilhelm, Karén, Brien, Donald C., Huang, Jeff, Coe, Brian C., Vadasz, David, Mayer, Geert, Munoz, Douglas P., Oertel, Wolfgang H.

“…Background Parkinson's disease (PD) patients exhibit deficits in saccade performance, pupil function, and blink rate. Isolated REM (rapid eye movement) Sleep…”
Get full text

Progression markers of motor deficits in Parkinson's disease: A biannual 4‐year prospective study by Heinzel, Sebastian, Bernhard, Felix P., Roeben, Benjamin, Nussbaum, Susanne, Heger, Tanja, Martus, Peter, Hobert, Markus A., Maetzler, Walter, Berg, Daniela

Get full text

Naturally occurring alpha-synuclein autoantibodies in Parkinson's disease: sources of (error) variance in biomarker assays by Heinzel, Sebastian, Gold, Maike, Deuschle, Christian, Bernhard, Felix, Maetzler, Walter, Berg, Daniela, Dodel, Richard

“…Alpha-synuclein (α-Syn) plays a pivotal role in the pathophysiology of Parkinson's disease (PD), which can partly be modulated by innate and adaptive immune…”
Get full text

Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease by Danielyan, Lusine, Schäfer, Richard, von Ameln-Mayerhofer, Andreas, Bernhard, Felix, Verleysdonk, Stephan, Buadze, Marine, Lourhmati, Ali, Klopfer, Tim, Schaumann, Felix, Schmid, Barbara, Koehle, Christoph, Proksch, Barbara, Weissert, Robert, Reichardt, Holger M, van den Brandt, Jens, Buniatian, Gayane H, Schwab, Matthias, Gleiter, Christoph H, Frey, 2nd, William H

“…Safe and effective cell delivery remains one of the main challenges in cell-based therapy of neurodegenerative disorders. Graft survival, sufficient enrichment…”
Get more information

No relevant association of kinematic gait parameters with Health-related Quality of Life in Parkinson's disease by Bettecken, Kristina, Bernhard, Felix, Sartor, Jennifer, Hobert, Markus A, Hofmann, Marc, Gladow, Till, van Uem, Janet M T, Liepelt-Scarfone, Inga, Maetzler, Walter

“…Health-related Quality of Life (HrQoL) is probably the most important outcome parameter for the evaluation and management of chronic diseases. As this…”
Get full text

Validation of the Geriatric Check in a cohort of hospitalized neurological patients by Hobert, Markus A, Bernhard, Felix P, Bettecken, Kristina, Sartor, Jennifer, Maetzler, Walter, Jamour, Michael

“…The Geriatrie-Check was developed as a screening tool for the identification of older patients with geriatric treatment requirements in hospitals. It was…”
Get full text

Parkinson’s disease: evolution of cognitive impairment and CSF Aβ1–42 profiles in a prospective longitudinal study by Lerche, Stefanie, Wurster, Isabel, Röben, Benjamin, Machetanz, Gerrit, Zimmermann, Milan, Bernhard, Felix, Stransky, Elke, Deuschle, Christian, Schulte, Claudia, Hansson, Oskar, Zetterberg, Henrik, Gasser, Thomas, Berg, Daniela, Maetzler, Walter, Brockmann, Kathrin

“…ObjectiveTo evaluate the evolution of cognitive impairment in relation to cerebrospinal fluid (CSF) profiles of amyloid-β (Aβ), total-Tau and…”
Get full text

White Matter Changes-Related Gait and Executive Function Deficits: Associations with Age and Parkinson's Disease by Sartor, Jennifer, Bettecken, Kristina, Bernhard, Felix P, Hofmann, Marc, Gladow, Till, Lindig, Tobias, Ciliz, Meltem, Ten Kate, Mara, Geritz, Johanna, Heinzel, Sebastian, Benedictus, Marije, Scheltens, Philip, Hobert, Markus A, Maetzler, Walter

“…White matter changes (WMC) are a common finding among older adults and patients with Parkinson's disease (PD), and have been associated with, e.g., gait…”
Get full text

Environmental sustainability: a strategic value in guiding cruise industry management by Carlos Eduardo de Almeida Ramoa, Luiz Carlos da Silva Flores, Felix Bernhard Herle

“…PurposeIn a systemic approach, a ship is a system in which people and organizations interact directly and indirectly in all processes from construction, during…”
Get full text

Distributed Computation in a Quadrupedal Robotic System by Kuehn, Daniel, Bernhard, Felix, Burchardt, Armin, Schilling, Moritz, Stark, Tobias, Zenzes, Martin, Kirchner, Frank

“…Today's and future space missions (will) have to deal with increasing requirements regarding autonomy and flexibility in the locomotor system. To cope with…”
Get full text

Corrigendum: White Matter Changes-Related Gait and Executive Function Deficits: Associations with Age and Parkinson's Disease by Sartor, Jennifer, Bettecken, Kristina, Bernhard, Felix P, Hofmann, Marc, Gladow, Till, Lindig, Tobias, Ciliz, Meltem, Ten Kate, Mara, Geritz, Johanna, Heinzel, Sebastian, Benedictus, Marije, Scheltens, Philip, Hobert, Markus A, Maetzler, Walter

“…[This corrects the article on p. 213 in vol. 9, PMID: 28713264.]…”
Get full text

Corporate Social Performance and the Likelihood of Bankruptcy: Evidence from a Period of Economic Upswing by Habermann, Florian, Fischer, Felix Bernhard

“…The paper aims to investigate the effects of corporate social performance (CSP) on bankruptcy likelihood in times of economic upswing. This is important…”
Get full text

Zombie Firms, Corporate Restructuring and Relationship Banking: Credit Guidance as a Key to Tackle Zombie Lending? by Fischer, Felix Bernhard

“…Abstract Economists have examined the rise of so-called zombie firms in recent years. Such firms remain in financial distress for a prolonged period while…”
Get full text

Four‐Year Follow‐up of [18F]Fluorodeoxyglucose Positron Emission Tomography–Based Parkinson's Disease–Related Pattern Expression in 20 Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder Shows Prodromal Progression by Kogan, Rosalie V., Janzen, Annette, Meles, Sanne K., Sittig, Elisabeth, Renken, Remco J., Gurvits, Vita, Mayer, Geert, Leenders, Klaus L., Oertel, Wolfgang H., Booij, Jan, Reetz, Kathrin, Overeem, Sebastiaan, Pijpers, Angelique, Bernhard, Felix, García, David Vállez, Peretti, Débora E., Teune, Laura K., Reesink, Fransje E., Kok, Jelmer G.

“…Background Isolated rapid eye movement sleep behavior disorder is known to be prodromal for alpha‐synucleinopathies, such as Parkinson's disease (PD) and…”
Get full text

Parkinson's disease: evolution of cognitive impairment and CSF Aβ 1-42 profiles in a prospective longitudinal study by Lerche, Stefanie, Wurster, Isabel, Röben, Benjamin, Machetanz, Gerrit, Zimmermann, Milan, Bernhard, Felix, Stransky, Elke, Deuschle, Christian, Schulte, Claudia, Hansson, Oskar, Zetterberg, Henrik, Gasser, Thomas, Berg, Daniela, Maetzler, Walter, Brockmann, Kathrin

“…To evaluate the evolution of cognitive impairment in relation to cerebrospinal fluid (CSF) profiles of amyloid-β (Aβ), total-Tau and phosphorylated-Tau in…”
Get full text

A Phase II Study to Evaluate the Safety and Efficacy of Prasinezumab in Early Parkinson's Disease (PASADENA): Rationale, Design, and Baseline Data by Pagano, Gennaro, Boess, Frank G, Taylor, Kirsten I, Ricci, Benedicte, Mollenhauer, Brit, Poewe, Werner, Boulay, Anne, Anzures-Cabrera, Judith, Vogt, Annamarie, Marchesi, Maddalena, Post, Anke, Nikolcheva, Tania, Kinney, Gene G, Zago, Wagner M, Ness, Daniel K, Svoboda, Hanno, Britschgi, Markus, Ostrowitzki, Susanne, Simuni, Tanya, Marek, Kenneth, Koller, Martin, Sevigny, Jeff, Doody, Rachelle, Fontoura, Paulo, Umbricht, Daniel, Bonni, Azad

“…Currently available treatments for Parkinson's disease (PD) do not slow clinical progression nor target alpha-synuclein, a key protein associated with the…”
Get full text

Naturally Occurring Alpha-Synuclein Autoantibodies in Parkinson's Disease: Sources of by Heinzel, Sebastian, Gold, Maike, Deuschle, Christian, Bernhard, Felix, Maetzler, Walter, Berg, Daniela, Dodel, Richard

“…Alpha-synuclein ([alpha]-Syn) plays a pivotal role in the pathophysiology of Parkinson's disease (PD), which can partly be modulated by innate and adaptive…”
Get full text