Search Results - "Berneman, Zwi N"

Clinical use of dendritic cells for cancer therapy by Anguille, Sébastien, Dr, Smits, Evelien L, Prof, Lion, Eva, van Tendeloo, Viggo F, Prof, Berneman, Zwi N, Prof

“…Summary Since the mid-1990s, dendritic cells have been used in clinical trials as cellular mediators for therapeutic vaccination of patients with cancer…”
Get full text

Safety and clinical efficacy of BCMA CAR-T-cell therapy in multiple myeloma by Roex, Gils, Timmers, Marijke, Wouters, Kristien, Campillo-Davo, Diana, Flumens, Donovan, Schroyens, Wilfried, Chu, Yiwei, Berneman, Zwi N, Lion, Eva, Luo, Feifei, Anguille, Sébastien

“…B-cell maturation antigen (BCMA)-targeted chimeric antigen receptor (CAR)-T-cell therapy is an emerging treatment option for multiple myeloma. The aim of this…”
Get full text

A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy by De Waele, Jorrit, Verhezen, Tias, van der Heijden, Sanne, Berneman, Zwi N, Peeters, Marc, Lardon, Filip, Wouters, An, Smits, Evelien L. J. M

“…Abstract Immunotherapy is currently under intensive investigation as a potential breakthrough treatment option for glioblastoma. Given the anatomical and…”
Get full text

Trial watch: Dendritic cell (DC)-based immunotherapy for cancer by Laureano, Raquel S, Sprooten, Jenny, Vanmeerbeerk, Isaure, Borras, Daniel M, Govaerts, Jannes, Naulaerts, Stefan, Berneman, Zwi N, Beuselinck, Benoit, Bol, Kalijn F, Borst, Jannie, Coosemans, an, Datsi, Angeliki, Fučíková, Jitka, Kinget, Lisa, Neyns, Bart, Schreibelt, Gerty, Smits, Evelien, Sorg, Rüdiger V, Spisek, Radek, Thielemans, Kris, Tuyaerts, Sandra, De Vleeschouwer, Steven, de Vries, I Jolanda M, Xiao, Yanling, Garg, Abhishek D

“…Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable development over recent decades. However, this field is currently in a state…”
Get full text

Antigen-Specific Treatment Modalities in MS: The Past, the Present, and the Future by Derdelinckx, Judith, Cras, Patrick, Berneman, Zwi N, Cools, Nathalie

“…Antigen-specific therapy for multiple sclerosis may lead to a more effective therapy by induction of tolerance to a wide range of myelin-derived antigens…”
Get full text

Two for one: targeting BCMA and CD19 in B-cell malignancies with off-the-shelf dual-CAR NK-92 cells by Roex, Gils, Campillo-Davo, Diana, Flumens, Donovan, Shaw, Philip Anthony Gilbert, Krekelbergh, Laurens, De Reu, Hans, Berneman, Zwi N, Lion, Eva, Anguille, Sébastien

“…Chimeric antigen receptor (CAR) T-cell therapy has proven to be a valuable new treatment option for patients with B-cell malignancies. However, by applying…”
Get full text

Chimeric Antigen Receptor-Modified T Cell Therapy in Multiple Myeloma: Beyond B Cell Maturation Antigen by Timmers, Marijke, Roex, Gils, Wang, Yuedi, Campillo-Davo, Diana, Van Tendeloo, Viggo F I, Chu, Yiwei, Berneman, Zwi N, Luo, Feifei, Van Acker, Heleen H, Anguille, Sébastien

“…Chimeric antigen receptor (CAR)-modified T cell therapy is a rapidly emerging immunotherapeutic approach that is revolutionizing cancer treatment. The…”
Get full text

Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination by Van Tendeloo, Viggo F., Van de Velde, Ann, Van Driessche, Ann, Cools, Nathalie, Anguille, Sébastien, Ladell, Kristin, Gostick, Emma, Vermeulen, Katrien, Pieters, Katrien, Nijs, Griet, Stein, Barbara, Smits, Evelien L., Schroyens, Wilfried A., Gadisseur, Alain P., Vrelust, Inge, Jorens, Philippe G., Goossens, Herman, de Vries, I. Jolanda, Price, David A., Oji, Yusuke, Oka, Yoshihiro, Sugiyama, Haruo, Berneman, Zwi N., Akira, Shizuo

“…Active immunization using tumor antigen-loaded dendritic cells holds promise for the adjuvant treatment of cancer to eradicate or control residual disease, but…”
Get full text

Tolerogenic Dendritic Cells Induce Apoptosis-Independent T Cell Hyporesponsiveness of SARS-CoV-2-Specific T Cells in an Antigen-Specific Manner by Van Delen, Mats, Janssens, Ibo, Dams, Amber, Roosens, Laurence, Ogunjimi, Benson, Berneman, Zwi N, Derdelinckx, Judith, Cools, Nathalie

“…Although the global pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still ongoing, there are currently no specific…”
Get full text

Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells by Van Acker, Heleen H, Anguille, Sébastien, Willemen, Yannick, Van den Bergh, Johan M, Berneman, Zwi N, Lion, Eva, Smits, Evelien L, Van Tendeloo, Viggo F

“…Adoptive immunotherapy is gaining momentum to fight malignancies, whereby γδ T cells have received recent attention as an alternative cell source as to natural…”
Get full text

The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer by Vermeulen, Katrien, Van Bockstaele, Dirk R., Berneman, Zwi N.

“…  The cell cycle is controlled by numerous mechanisms ensuring correct cell division. This review will focus on these mechanisms, i.e. regulation of…”
Get full text

The Use of TLR7 and TLR8 Ligands for the Enhancement of Cancer Immunotherapy by Smits, Evelien L. J. M., Ponsaerts, Peter, Berneman, Zwi N., Van Tendeloo, Viggo F. I.

“…Learning Objectives After completing this course, the reader should be able to: Describe the subtypes of Toll‐like receptor 7 and 8 agonists and their effect…”
Get full text

Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner by Anguille, Sébastien, Van Acker, Heleen H, Van den Bergh, Johan, Willemen, Yannick, Goossens, Herman, Van Tendeloo, Viggo F, Smits, Evelien L, Berneman, Zwi N, Lion, Eva

“…The contribution of natural killer (NK) cells to the treatment efficacy of dendritic cell (DC)-based cancer vaccines is being increasingly recognized. Much…”
Get full text

Balancing between immunity and tolerance: an interplay between dendritic cells, regulatory T cells, and effector T cells by Cools, Nathalie, Ponsaerts, Peter, Van Tendeloo, Viggo F. I., Berneman, Zwi N.

“…Dendritic cells (DC), professional antigen‐presenting cells of the immune system, exert important functions both in induction of T cell immunity, as well as…”
Get full text

NK Cells: Key to Success of DC‐Based Cancer Vaccines? by Lion, Eva, Smits, Evelien L.J.M., Berneman, Zwi N., Van Tendeloo, Viggo F.I.

“…Learning Objectives After completing this course, the reader will be able to: Describe the current in vivo experimental and clinical dendritic cell (DC)…”
Get full text

Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion by Van Acker, Heleen H, Anguille, Sébastien, De Reu, Hans, Berneman, Zwi N, Smits, Evelien L, Van Tendeloo, Viggo F

“…Dendritic cell (DC) vaccination can be an effective post-remission therapy for acute myeloid leukemia (AML). Yet, current DC vaccines do not encompass the…”
Get full text

12 Weeks of Combined Endurance and Resistance Training Reduces Innate Markers of Inflammation in a Randomized Controlled Clinical Trial in Patients with Multiple Sclerosis by O Eijnde, Bert, Cools, Nathalie, Berneman, Zwi N., Goossens, Herman, Koppen, Gudrun, De Winter, Benedicte, Hens, Niel, Nuyts, Amber H., Wens, Inez, Deckx, Nathalie, Van Damme, Pierre

“…Previously, we reported that patients with multiple sclerosis (MS) demonstrate improved muscle strength, exercise tolerance, and lean tissue mass following a…”
Get full text

The Ins and Outs of Messenger RNA Electroporation for Physical Gene Delivery in Immune Cell-Based Therapy by Campillo-Davo, Diana, De Laere, Maxime, Roex, Gils, Versteven, Maarten, Flumens, Donovan, Berneman, Zwi N, Van Tendeloo, Viggo F I, Anguille, Sébastien, Lion, Eva

“…Messenger RNA (mRNA) electroporation is a powerful tool for transient genetic modification of cells. This non-viral method of genetic engineering has been…”
Get full text

Apoptosis: mechanisms and relevance in cancer by Vermeulen, Katrien, Van Bockstaele, Dirk R, Berneman, Zwi N

“…Apoptosis or programmed cell death is a process with typical morphological characteristics including plasma membrane blebbing, cell shrinkage, chromatin…”
Get full text

Clinical and immunological control of experimental autoimmune encephalomyelitis by tolerogenic dendritic cells loaded with MOG-encoding mRNA by Derdelinckx, Judith, Mansilla, María José, De Laere, Maxime, Lee, Wai-Ping, Navarro-Barriuso, Juan, Wens, Inez, Nkansah, Irene, Daans, Jasmijn, De Reu, Hans, Jolanta Keliris, Aneta, Van Audekerke, Johan, Vanreusel, Verdi, Pieters, Zoë, Van der Linden, Annemie, Verhoye, Marleen, Molenberghs, Geert, Hens, Niel, Goossens, Herman, Willekens, Barbara, Cras, Patrick, Ponsaerts, Peter, Berneman, Zwi N, Martínez-Cáceres, Eva María, Cools, Nathalie

“…Although effective in reducing relapse rate and delaying progression, current therapies for multiple sclerosis (MS) do not completely halt disease progression…”
Get full text