Search Results - "Berndtsson, M."

Effects of the oral, direct factor Xa inhibitor apixaban on routine coagulation assays and anti‐FXa assays by Hillarp, A., Gustafsson, K. M., Faxälv, L., Strandberg, K., Baghaei, F., Fagerberg Blixter, I., Berndtsson, M., Lindahl, T. L.

“…Summary Introduction Apixaban is an oral direct factor Xa inhibitor developed for the prophylaxis and treatment of thromboembolic disorders. Laboratory…”
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Cisplatin and Oxaliplatin Toxicity: Importance of Cochlear Kinetics as a Determinant for Ototoxicity by Hellberg, Victoria, Wallin, Inger, Eriksson, Sofi, Hernlund, Emma, Jerremalm, Elin, Berndtsson, Maria, Eksborg, Staffan, Arnér, Elias S. J., Shoshan, Maria, Ehrsson, Hans, Laurell, Göran

“…Background Cisplatin is a cornerstone anticancer drug with pronounced ototoxicity, whereas oxaliplatin, a platinum derivative with a different clinical…”
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C0144: Is there a Role for Standard Thrombin Time (TT) Measurements for the Monitoring of Low Levels of Dabigatran? by Antovic, J.P, Berndtsson, M, Malmström, R.E, Thalen, S, Pohanka, A, Norberg, E.-M, Rönquist, Y, Hjemdahl, P

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C0234: Assessment of the Diagnostic Algorithm for Heparin-Induced Thrombocytopenia by Farm Stephanie, M, Bakchoul, T, Frisk, T, Odenrick, A, Althaus, K, Norberg, E.-M, Berndtsson, M, Greinacher, A, Antovic, J

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Analyzing course configurations for teaching object-oriented modeling and design by Berndtsson, M.

“…This paper presents and analyzes an object-oriented analysis and design course that has been given in three different configurations for students who are…”
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Specific demonstration of drug-induced tumour cell apoptosis in human xenografts models using a plasma biomarker by Olofsson, M Hägg, Cummings, J, Fayad, W, Brnjic, S, Herrmann, R, Berndtsson, M, Hodgkinson, C, Dean, E, Odedra, R, Wilkinson, R W, Mundt, K E, Busk, M, Dive, C, Linder, S

“…Pharmacodynamic (PD) assays should be used before advancing new drugs to clinical trials. Most PD assays measure the response to drugs in tissue, a procedure…”
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Effects of direct oral anticoagulants on lupus anticoagulant assays in a real-life setting by Antovic, Aleksandra, Norberg, Eva-Marie, Berndtsson, Maria, Rasmuson, Agnes, Malmström, Rickard E, Skeppholm, Mika, Antovic, Jovan

“…Laboratory diagnosis of lupus anticoagulant (LA) is based on prolongation in at least one coagulation assay (diluted Russell's viper venom time - dRVVT or…”
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Clinical evaluation of laboratory methods tomonitor apixaban treatment in patients with atrial fibrillation by Skeppholm, M, Al-Aieshy, F, Berndtsson, M, Al-Khalili, F, Ronquist-Nii, Y, Soderblom, L, Ostlund, AY, Pohanka, A, Antovic, J, Malmstrom, RE

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Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA by Berndtsson, Maria, Hägg, Maria, Panaretakis, Theocharis, Havelka, Aleksandra Mandic, Shoshan, Maria C., Linder, Stig

“…Cisplatin is a broad‐spectrum anticancer drug that is also widely used in experimental studies on DNA damage‐induced apoptosis. Induction of apoptosis within…”
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Clinical evaluation of laboratory methods to monitor apixaban treatment in patients with atrial fibrillation by Skeppholm, Mika, Al-Aieshy, Fadiea, Berndtsson, Maria, Al-Khalili, Faris, Rönquist-Nii, Yuko, Söderblom, Lisbeth, Östlund, Annika Y, Pohanka, Anton, Antovic, Jovan, Malmström, Rickard E

“…Abstract Introduction The direct factor-Xa inhibitor apixaban is approved e.g. for the prevention of stroke in patients with atrial fibrillation (AF). Although…”
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Difference in Fibrin Clot Structure in Haemophilia A and Haemophilia B by Luong, Vincent, Soutari, Nida, Berndtsson, Maria, Holmström, Margareta, Antovic, Jovan P., Chaireti, Roza

“…Introduction: Hemophilia A and Hemophilia B are X-linked bleeding disorders characterized by deficiency of coagulation factor VIII and IX respectively. The…”
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Clinical evaluation of laboratory methods to monitor exposure of rivaroxaban at trough and peak in patients with atrial fibrillation by Al-Aieshy, Fadiea, Malmström, Rickard E, Antovic, Jovan, Pohanka, Anton, Rönquist-Nii, Yuko, Berndtsson, Maria, Al-Khalili, Faris, Skeppholm, Mika

“…Purpose The one-dose daily regime of rivaroxaban could cause a pronounced variability in concentration and effect of which a deeper knowledge is warranted…”
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Induction of Lysosomal Membrane Permeabilization by Compounds That Activate p53-Independent Apoptosis by Erdal, Hamdiye, Berndtsson, Maria, Castro, Juan, Brunk, Ulf, Shoshan, Maria C., Linder, Stig, Sachs, Leo

“…The p53 protein activates cellular death programs through multiple pathways. Because the high frequency of p53 mutations in human tumors is believed to…”
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Screening for compounds that induce apoptosis of cancer cells grown as multicellular spheroids by Herrmann, Richard, Fayad, Walid, Schwarz, Stephan, Berndtsson, Maria, Linder, Stig

“…Screening and initial characterization of anticancer drugs are typically performed using monolayer cultures of tumor cells. It is well established that such…”
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Evaluation of a diagnostic algorithm for Heparin-Induced Thrombocytopenia by Farm, Maria, Bakchoul, Tamam, Frisk, Tony, Althaus, Karina, Odenrick, Alice, Norberg, Eva-Marie, Berndtsson, Maria, Antovic, Jovan P

“…Abstract Introduction Heparin-Induced Thrombocytopenia (HIT) is a rare but serious immune-mediated complication of heparin treatment. HIT is characterized by…”
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Feasibility, usability and acceptability of a novel digital hybrid-system for reporting of routine maternal health information in Southern Tanzania: A mixed-methods study by Unkels, Regine, Manzi, Fatuma, Kapologwe, Ntuli A, Baker, Ulrika, Ahmad, Aziz, Nabiev, Rustam, Berndtsson, Maria, Baraka, Jitihada, Hanson, Claudia, Hirose, Atsumi

“…Health information systems are important for health planning and progress monitoring. Still, data from health facilities are often of limited quality in…”
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Thrombin generation test in children and adolescents with chronic liver disease by Magnusson, Maria, Berndtsson, Maria, Fischler, Björn, Petrini, Pia, Schulman, Sam, Renne, Thomas, Granath, Anna, Sten-Linder, Margareta, Németh, Antal

“…Abstract Introduction The aim of this study was to evaluate if real-time thrombin generation assay provides additional information to assess the hemostatic…”
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Does the intensity and quality of treatment and not only the factor viii level influence global hemostasis in patients with hemophilia a? by Berndtsson, Maria, Zetterberg, Eva, Holmström, Margareta, Mahmoud Hourani Soutari, Nida, Mikovic, Danijela, Elezovic, Ivo, Antovic, Jovan P

“…Highligths • The quality of treatment influences the hemostatic capacity in hemophilia A patients • Patients receiving higher intensity treatment had better…”
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Restriction of cisplatin induction of acute apoptosis to a subpopulation of cells in a three‐dimensional carcinoma culture model by Fayad, Walid, Brnjic, Slavica, Berglind, Daniel, Blixt, Susanna, Shoshan, Maria C., Berndtsson, Maria, Olofsson, Maria Hägg, Linder, Stig

“…Cisplatin is a clinically important chemotherapeutical agent used to treat epithelial malignancies. High concentrations (20–100 μM) of cisplatin have been used…”
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Mechanisms of action of DNA-damaging anticancer drugs in treatment of carcinomas: is acute apoptosis an "off-target" effect? by Havelka, Aleksandra Mandic, Berndtsson, Maria, Olofsson, Maria Hägg, Shoshan, Maria C, Linder, Stig

“…DNA damage induces apoptosis of cells of hematological origin. Apoptosis is also widely believed to be the major antiproliferative mechanism of DNA damaging…”
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