Search Results - "Bernauer, U"

The use of metabolising systems for in vitro testing of endocrine disruptors by Jacobs, M N, Janssens, W, Bernauer, U, Brandon, E, Coecke, S, Combes, R, Edwards, P, Freidig, A, Freyberger, A, Kolanczyk, R, Mc Ardle, C, Mekenyan, O, Schmieder, P, Schrader, T, Takeyoshi, M, van der Burg, B

“…Legislation and prospective legislative proposals in for instance the USA, Europe, and Japan require, or may require that chemicals are tested for their…”
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Comparative male reproductive toxicity of selected phthalates by Bernauer, U., Rosenthal, E., Heinrich-Hirsch, B., Schulte, A.

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Biotransformation of MTBE, ETBE, and TAME after inhalation or ingestion in rats and humans by Dekant, W, Bernauer, U, Rosner, E, Amberg, A

“…The biotransformation of methyl tert-butyl ether (MTBE), ethyl tert-butyl ether (ETBE), and tert-amyl methyl ether (TAME) was studied in humans and in rats…”
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Opinion of the Scientific Committee on Consumer safety (SCCS) – Revision of the opinion on the safety of the use of titanium dioxide, nano form, in cosmetic products by SCCS, Chaudhry, Qasim

“…•The use of TiO2 nano up to 25% as a UV-filter in sunscreens can be considered safe within the limits of the Opinion.•This Opinion does not apply when…”
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Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches by Coecke, Sandra, Pelkonen, Olavi, Leite, Sofia Batista, Bernauer, Ulrike, Bessems, Jos GM, Bois, Frederic Y., Gundert-Remy, Ursula, Loizou, George, Testai, Emanuela, Zaldívar, José-Manuel

“…► Toxicokinetics (TK) is a key element to integrate the results from in silico, in vitro and in vivo studies. ► TK is needed to estimate target organ doses…”
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Expression of cytochrome P450 enzymes in human colon by Bernauer, U, Ellrich, R, Heinrich-Hirsch, B, Teubner, W, Vieth, B, Gundert-Remy, U

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Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation by Mech, A., Rasmussen, K., Jantunen, P., Aicher, L., Alessandrelli, M., Bernauer, U., Bleeker, E. A. J., Bouillard, J., Di Prospero Fanghella, P., Draisci, R., Dusinska, M., Encheva, G., Flament, G., Haase, A., Handzhiyski, Y., Herzberg, F., Huwyler, J., Jacobsen, N. R., Jeliazkov, V., Jeliazkova, N., Nymark, P., Grafström, R., Oomen, A. G., Polci, M. L., Riebeling, C., Sandström, J., Shivachev, B., Stateva, S., Tanasescu, S., Tsekovska, R., Wallin, H., Wilks, M. F., Zellmer, S., Apostolova, M. D.

“…This paper presents a comprehensive review of European Union (EU) legislation addressing the safety of chemical substances, and possibilities within each piece…”
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Guidelines on the benefit-risk assessment of the presence of phthalates in certain medical devices covering phthalates which are carcinogenic, mutagenic, toxic to reproduction (CMR) or have endocrine-disrupting (ED) properties by De Jong, W.H., De Jong, W.H., Borges, T., Ion, R.M., Panagiotakos, D., Testai, E., Vermeire, T., Bernauer, U., Rousselle, C., Bégué, Sté, Kopperud, H.M., Milana, M.R., Schmidt, T., Pignatti, F., Stoyanova, E., Volk, K., Bertollini, R., De Voogt, P., Duarte-Davidson, R., Hoet, P., Kraetke, R., Proykova, A., Samaras, T., Scott, M., Slama, R., Vighi, M., Zacharo, S.

“…By the new Medical Device Regulation (MDR, EU 2017/745) the use of certain phthalates which are carcinogenic, mutagenic, toxic to reproduction (CMR) or have…”
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Opinion of the scientific committee on consumer safety (SCCS) – Opinion on the safety of cosmetic ingredient phenylene bis-diphenyltriazine (CAS No 55514-22-2) - S86 by Bernauer, U., Bodin, L., Chaudhry, Q., Coenraads, P.J., Dusinska, M., Ezendam, J., Gaffet, E., Galli, C.L., Granum, B., Panteri, E., Rogiers, V., Rousselle, Ch, Stepnik, M., Vanhaecke, T., Wijnhoven, S., Koutsodimou, A., Simonnard, A., Uter, W., Rousselle, Christophe

“…Based on the data provided in the dossier, the SCCS considers Phenylene Bis-Diphenyltriazine, S86, safe for use as a UV-filter in sunscreen products at a…”
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Opinion of the Scientific Committee on Consumer Safety (SCCS) – Opinion on the safety of the use of β-arbutin in cosmetic products by SCCS, Degen, Gisela H.

“…The SCCS considers the use of β-arbutin to be safe for consumers in cosmetic products in a concentration up to 7% in face creams provided that the…”
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REACH Compliance Project: Alternative methods to animal testing in REACH registrations on high tonnage chemicals – Data waiving and adaptation by Kronsbein, Anna Lena, Maul, Katrin, Menz, Jakob, Oertel, Angelika, Sittner, Dana, Springer, Andrea, Bernauer, Ulrike, Herbst, Uta, Schulte, Agnes

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Opinion of the scientific committee on consumer safety (SCCS) – Final opinion on Polyaminopropyl Biguanide (PHMB) in cosmetic products - Submission III by Bernauer, U., Bodin, L., Chaudhry, Q., Coenraads, P.J., Dusinska, M., Ezendam, E., Galli, C.L., Granum, B., Panteri, E., Rogiers, V., Rousselle, Ch, Stepnik, M., Vanhaecke, T., Wijnhoven, S., Rogiers, Vera

“…•The SCCS considers the use of the Polyaminopropyl Biguanide not safe up to maximal concentration of 0.3% as preservative.•The use of Polyaminopropyl Biguanide…”
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Opinion of the Scientific Committee on Consumer Safety (SCCS) – Revision of the opinion on the safety of the use of Silica, Hydrated Silica, and Silica Surface Modified with Alkyl Silylates (nano form) in cosmetic products by SCCS, Hoet, P.H.M.

“…The SCCS has concluded that the evidence, both provided in the submission and that available in scientific literature, is inadequate and insufficient to allow…”
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Opinion of the scientific committee on consumer safety (SCCS) – Final version of the opinion on Ethylzingerone - ‘Hydroxyethoxyphenyl Butanone’ (HEPB) - Cosmetics Europe No P98 - in cosmetic products by Bernauer, U., Bodin, L., Chaudhry, Q., Coenraads, P.J., Dusinska, M., Ezendam, E., Galli, C.L., Granum, B., Panteri, E., Rogiers, V., Rousselle, Ch, Stepnik, M., Vanhaecke, T., Wijnhoven, S., Bernauer, Ulrike

“…•The SCCS considers the use of HEPB as a cosmetic preservative in rinse-off with a maximum concentration of 2.0% not safe.•Same for oral care and leave-on…”
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Opinion of the Scientific Committee on Consumer safety (SCCS) – Opinion on Ethylzingerone - ‘Hydroxyethoxyphenyl Butanone’ (HEPB) - Cosmetics Europe No P98 - CAS No 569646-79-3 - Submission II (eye irritation) by Bernauer, Ulrike, Bodin, Laurent, Chaudhry, Qasim, Coenraads, Pieter, Dusinska, Maria, Ezendam, Janine, Gaffet, Eric, Galli, Corrado Lodovico, Granum, Berit Brunstad, Panteri, Eirini, Rogiers, Vera, Rousselle, Christophe, Stępnik, Maciej, Vanhaecke, Tamara, Wijnhoven, Susan, Koutsodimou, Aglaia, Simonnard, Alain, Uter, Wolfgang

“…Based on the new information provided by the Applicant, the SCCS considers the use of Hydroxyethoxyphenyl Butanone (HEPB) as a cosmetic preservative in…”
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Opinion of the Scientific Committee on Consumer safety (SCCS) – Opinion on the safety of the use of Methylisothiazolinone (MI) (P94), in cosmetic products (sensitisation only) by Scientific Committee of Consumer Safety – SCCS, Giménez-Arnau, A.M.

“…The information provided does not support the safe use of MI as a preservative in rinse-off cosmetic products up to a concentration limit of 100 ppm from the…”
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Opinion of the Scientific Committee on Consumer safety (SCCS) – Opinion on the safety of the use of deoxyarbutin in cosmetic products by SCCS, Degen, Gisela H.

“…Although on the basis of the provided scientific data the use of deoxyarbutin as such can be considered safe for consumers in cosmetic products in a…”
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Opinion of the Scientific Committee on Consumer Safety (SCCS) – Final version of the opinion on Phenoxyethanol in cosmetic products by Lilienblum, Werner

“…The SCCS considers 2-phenoxyethanol safe for use as a preservative with a maximum concentration of 1.0%, taking into account the information provided. The…”
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Opinion of the Scientific Committee on Consumer Safety (SCCS) – Final version of the opinion on decamethylcyclopentasiloxane (cyclopentasiloxane, D5) in cosmetic products by Rousselle, Dr Christophe

“…•The use of Cyclopentasiloxane (D5) in cosmetic products is safe at the reported concentrations.•However Cyclopentasiloxane is not safe in hair styling…”
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Revision of the opinion on hydrolysed wheat proteins – Sensitisation only by Scientific Committee SCCS, Coenraads, Pieter-Jan

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