Search Results - "Bernaudo, Stefanie"
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Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis
Published in Journal of ovarian research (11-12-2019)“…Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/β-catenin pathway plays critical roles in regulating embryonic development and…”
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miR-590-3p Targets Cyclin G2 and FOXO3 to Promote Ovarian Cancer Cell Proliferation, Invasion, and Spheroid Formation
Published in International journal of molecular sciences (12-04-2019)“…Ovarian cancer is the leading cause of death from gynecological cancers. MicroRNAs (miRNAs) are small, non-coding RNAs that interact with the 3' untranslated…”
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miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2-Versican Pathway
Published in Cancer research (Chicago, Ill.) (01-08-2018)“…miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this…”
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Epidermal growth factor promotes cyclin G2 degradation via calpain-mediated proteolysis in gynaecological cancer cells
Published in PloS one (22-06-2017)“…Cyclin G2 (CCNG2) is an atypical cyclin that functions to inhibit cell cycle progression and is often dysregulated in human cancers. We have previously shown…”
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MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance
Published in Journal of cell science (01-02-2011)“…MicroRNAs (miRNAs) are small noncoding RNAs that have important roles in gene regulation. We have previously reported that activin receptor-like kinase 7…”
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Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7
Published in Molecular biology of the cell (01-11-2008)“…We have previously reported that Nodal, a member of the TGF-beta superfamily, acts through activin receptor-like kinase 7 (ALK7) to inhibit ovarian cancer cell…”
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Wnt/[beta]-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis
Published in Journal of ovarian research (11-12-2019)“…Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/[beta]-catenin pathway plays critical roles in regulating embryonic development and…”
Get full text
Journal Article