Search Results - "Bernatchez, Emilie"
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Countering the advert effects of lung cancer on the anticancer potential of dendritic cell populations reinstates sensitivity to anti-PD-1 therapy
Published in PloS one (30-11-2021)“…Lung cancer is the leading cause of cancer-related deaths. While the recent use of immune checkpoint inhibitors significantly improves patient outcomes,…”
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Lipopolysaccharide impacts murine CD103+ DC differentiation, altering the lung DC population balance
Published in European journal of immunology (01-04-2019)“…Conventional DCs are a heterogeneous population that bridge the innate and adaptive immune systems. The lung DC population comprises CD103+XCR1+ DC1s and…”
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Pulmonary CD103 expression regulates airway inflammation in asthma
Published in American journal of physiology. Lung cellular and molecular physiology (15-04-2015)“…Although CD103(+) cells recently emerged as key regulatory cells in the gut, the role of CD103 ubiquitous expression in the lung and development of allergic…”
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4
Exposure to the Gram-Negative Bacteria Pseudomonas aeruginosa Influences the Lung Dendritic Cell Population Signature by Interfering With CD103 Expression
Published in Frontiers in cellular and infection microbiology (06-07-2021)“…Lung dendritic cells (DCs) are divided into two major populations, which include CD103 + XCR1 + cDC1s and CD11b + Sirpα + cDC2s. The maintenance of their…”
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Hypersensitivity pneumonitis onset and severity is regulated by CD103 dendritic cell expression
Published in PloS one (19-06-2017)“…Pulmonary dendritic cells drive lung responses to foreign antigens, including Saccharopolyspora rectivirgula, a causative agent of hypersensitivity…”
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Human and Mouse Eosinophils Differ in Their Ability to Biosynthesize Eicosanoids, Docosanoids, the Endocannabinoid 2-Arachidonoyl-glycerol and Its Congeners
Published in Cells (Basel, Switzerland) (02-01-2022)“…High eosinophil (EOS) counts are a key feature of eosinophilic asthma. EOS notably affect asthmatic response by generating several lipid mediators. Mice have…”
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CD34 regulates the skeletal muscle response to hypoxia
Published in Journal of muscle research and cell motility (01-12-2019)“…Chronic obstructive pulmonary disease (COPD) can sometimes be associated with skeletal muscle atrophy. Hypoxemic episodes, which occur during disease…”
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CD103 expression by DCs: a new player in lung cancer immunity
Published in The Journal of immunology (1950) (01-05-2018)“…Abstract Despite the use of various therapies, lung cancer remains one of the world’s leading causes of death. Cancer immunotherapy is a promising therapeutic…”
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Altering the dendritic cell signature in the lung: a new adjuvant to immune checkpoint inhibitor therapies?
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Lung cancer is the leading cause of cancer-related death. While the recent introduction of immune checkpoint immunotherapies significantly improves…”
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10
The effect of LPS on CD103 expression on dendritic cells
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Control of the intensity and duration of the pulmonary immune response is crucial in homeostasis maintenance in the lung. Dendritic cells (DCs), the…”
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S1P 1 Contributes to Endotoxin-enhanced B Cell Functions Involved in Hypersensitivity Pneumonitis
Published in American journal of respiratory cell and molecular biology (01-08-2020)“…In a proportion of patients with hypersensitivity pneumonitis, biological and environmental factors sustaining inflammation are ill-defined, resulting in no…”
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CD103 expression on DCs regulates the onset and severity of TH17 airway inflammation
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Pulmonary dendritic cells (DCs) drive TH17 immunopathological responses to foreign antigens, including Saccharopolyspora rectivirgula (SR), a…”
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S1P1 Contributes to Endotoxin-enhanced B-Cell Functions Involved in Hypersensitivity Pneumonitis
Published in American journal of respiratory cell and molecular biology (01-08-2020)“…Huppe et al discuss their study on the impact of endotoxins on B-cell activation in preexisting hypersensitivity pneumonitis and the role of S1P1 in this…”
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Environmental bioaerosol antigen Methanosphaera stadtmanae induces a TH17 inflammatory lung response via TLR4 signaling
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Bioaerosols in occupational environments are highly associated with the development of inflammatory lung diseases. The archaea specie Methanosphaera…”
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Methanosphaera stadtmanae induces a type IV hypersensitivity response in a mouse model of airway inflammation
Published in Physiological reports (01-04-2017)“…Despite improved awareness of work‐related diseases and preventive measures, many workers are still at high risk of developing occupational hypersensitivity…”
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16
AllerGen’s 8th research conference
Published in Allergy, asthma, and clinical immunology (08-12-2016)Get full text
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17
Human and murine eosinophils differ in their ability to synthesize key bioactive lipids involved in asthma
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract CONTEXT High eosinophil (EOS) counts is a key feature of asthma. EOS notably affect the asthmatic response by the mean of their lipidome. Mouse models…”
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Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma
Published in Respiratory research (03-02-2015)“…In vivo phosphorylation of sphingosine analogs with their ensuing binding and activation of their cell-surface sphingosine-1-phosphate receptors is regarded as…”
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