Search Results - "Bernardo, S"

Necroptosis, pyroptosis and apoptosis: an intricate game of cell death by Bertheloot, Damien, Latz, Eicke, Franklin, Bernardo S.

“…Cell death is a fundamental physiological process in all living organisms. Its roles extend from embryonic development, organ maintenance, and aging to the…”
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Large Bulk Photovoltaic Effect and Spontaneous Polarization of Single-Layer Monochalcogenides by Rangel, Tonatiuh, Fregoso, Benjamin M, Mendoza, Bernardo S, Morimoto, Takahiro, Moore, Joel E, Neaton, Jeffrey B

“…We use a first-principles density functional theory approach to calculate the shift current and linear absorption of uniformly illuminated single-layer Ge and…”
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NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain by Stutz, Andrea, Kolbe, Carl-Christian, Stahl, Rainer, Horvath, Gabor L, Franklin, Bernardo S, van Ray, Olivia, Brinkschulte, Rebecca, Geyer, Matthias, Meissner, Felix, Latz, Eicke

“…NLRP3 is a cytosolic pattern recognition receptor that senses microbes and endogenous danger signals. Upon activation, NLRP3 forms an inflammasome with the…”
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Long-Term Ozone Exposure and Mortality in a Large Prospective Study by Turner, Michelle C, Jerrett, Michael, Pope, 3rd, C Arden, Krewski, Daniel, Gapstur, Susan M, Diver, W Ryan, Beckerman, Bernardo S, Marshall, Julian D, Su, Jason, Crouse, Daniel L, Burnett, Richard T

“…Tropospheric ozone (O3) is potentially associated with cardiovascular disease risk and premature death. Results from long-term epidemiological studies on O3…”
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Crystal Formation in Inflammation by Franklin, Bernardo S, Mangan, Matthew S, Latz, Eicke

“…The formation and accumulation of crystalline material in tissues is a hallmark of many metabolic and inflammatory conditions. The discovery that the phase…”
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The Inflammasomes and Autoinflammatory Syndromes by Broderick, Lori, De Nardo, Dominic, Franklin, Bernardo S, Hoffman, Hal M, Latz, Eicke

“…Inflammation, a vital response of the immune system to infection and damage to tissues, can be initiated by various germline-encoded innate immune-signaling…”
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The intra‐ and extracellular functions of ASC specks by Franklin, Bernardo S, Latz, Eicke, Schmidt, Florian Ingo

“…Summary Inflammasomes are the central signaling hubs of the inflammatory response. They process cytosolic evidence of infection, cell damage, or metabolic…”
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Endothelial Microparticle–Mediated Transfer of MicroRNA-126 Promotes Vascular Endothelial Cell Repair via SPRED1 and Is Abrogated in Glucose-Damaged Endothelial Microparticles by Jansen, Felix, Yang, Xiaoyan, Hoelscher, Marion, Cattelan, Arianna, Schmitz, Theresa, Proebsting, Sebastian, Wenzel, Daniela, Vosen, Sarah, Franklin, Bernardo S, Fleischmann, Bernd K, Nickenig, Georg, Werner, Nikos

“…BACKGROUND—Repair of the endothelium after vascular injury is crucial for preserving endothelial integrity and preventing the development of vascular disease…”
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LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer by Tavazoie, Masoud F., Pollack, Ilana, Tanqueco, Raissa, Ostendorf, Benjamin N., Reis, Bernardo S., Gonsalves, Foster C., Kurth, Isabel, Andreu-Agullo, Celia, Derbyshire, Mark L., Posada, Jessica, Takeda, Shugaku, Tafreshian, Kimia N., Rowinsky, Eric, Szarek, Michael, Waltzman, Roger J., Mcmillan, Elizabeth A., Zhao, Connie, Mita, Monica, Mita, Alain, Chmielowski, Bartosz, Postow, Michael A., Ribas, Antoni, Mucida, Daniel, Tavazoie, Sohail F.

“…Therapeutic harnessing of adaptive immunity via checkpoint inhibition has transformed the treatment of many cancers. Despite unprecedented long-term responses,…”
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Regulation of Innate Immune Responses by Platelets by Ribeiro, Lucas Secchim, Migliari Branco, Laura, Franklin, Bernardo S

“…The role of platelets has been extensively studied in the context of coagulation and vascular integrity. Their hemostatic imbalance can lead to known…”
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Transcription Factor T-bet Regulates Intraepithelial Lymphocyte Functional Maturation by Reis, Bernardo S., Hoytema van Konijnenburg, David P., Grivennikov, Sergei I., Mucida, Daniel

“…The intestinal epithelium harbors large populations of activated and memory lymphocytes, yet these cells do not cause tissue damage in the steady state…”
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Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease by Venegas, Carmen, Kumar, Sathish, Franklin, Bernardo S., Dierkes, Tobias, Brinkschulte, Rebecca, Tejera, Dario, Vieira-Saecker, Ana, Schwartz, Stephanie, Santarelli, Francesco, Kummer, Markus P., Griep, Angelika, Gelpi, Ellen, Beilharz, Michael, Riedel, Dietmar, Golenbock, Douglas T., Geyer, Matthias, Walter, Jochen, Latz, Eicke, Heneka, Michael T.

“…The spreading of pathology within and between brain areas is a hallmark of neurodegenerative disorders. In patients with Alzheimer’s disease, deposition of…”
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Soluble Uric Acid Activates the NLRP3 Inflammasome by Braga, Tarcio Teodoro, Forni, Maria Fernanda, Correa-Costa, Matheus, Ramos, Rodrigo Nalio, Barbuto, Jose Alexandre, Branco, Paola, Castoldi, Angela, Hiyane, Meire Ioshie, Davanso, Mariana Rodrigues, Latz, Eicke, Franklin, Bernardo S., Kowaltowski, Alicia J., Camara, Niels Olsen Saraiva

“…Uric acid is a damage-associated molecular pattern (DAMP), released from ischemic tissues and dying cells which, when crystalized, is able to activate the…”
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Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a Dynamic Response to Infection by Hoytema van Konijnenburg, David P., Reis, Bernardo S., Pedicord, Virginia A., Farache, Julia, Victora, Gabriel D., Mucida, Daniel

“…Intestinal intraepithelial lymphocytes (IELs) are located at the critical interface between the intestinal lumen, which is chronically exposed to food and…”
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BARGAINING WITH ASYMMETRIC INFORMATION: AN EMPIRICAL STUDY OF PLEA NEGOTIATIONS by Silveira, Bernardo S.

“…This paper empirically investigates how sentences to be assigned at trial impact plea bargaining. The analysis is based on the model of bargaining with…”
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An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice by Ludwig-Portugall, Isis, Bartok, Eva, Dhana, Ermanila, Evers, Beatrix D G, Primiano, Michael J, Hall, J Perry, Franklin, Bernardo S, Knolle, Percy A, Hornung, Veit, Hartmann, Gunther, Boor, Peter, Latz, Eicke, Kurts, Christian

“…Intrarenal crystal formation activates the Nlrp3 inflammasome in myeloid cells and triggers a profound inflammatory response. Here, we studied whether a…”
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Comparing the Health Effects of Ambient Particulate Matter Estimated Using Ground-Based versus Remote Sensing Exposure Estimates by Jerrett, Michael, Turner, Michelle C, Beckerman, Bernardo S, Pope, C Arden, van Donkelaar, Aaron, Martin, Randall V, Serre, Marc, Crouse, Dan, Gapstur, Susan M, Krewski, Daniel, Diver, W Ryan, Coogan, Patricia F, Thurston, George D, Burnett, Richard T

“…Remote sensing (RS) is increasingly used for exposure assessment in epidemiological and burden of disease studies, including those investigating whether…”
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Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges by Silva, Hernandez Moura, Báfica, André, Rodrigues-Luiz, Gabriela Flavia, Chi, Jingyi, Santos, Patricia d'Emery Alves, Reis, Bernardo S, Hoytema van Konijnenburg, David P, Crane, Audrey, Arifa, Raquel Duque Nascimento, Martin, Patricia, Mendes, Daniel Augusto G B, Mansur, Daniel Santos, Torres, Victor J, Cadwell, Ken, Cohen, Paul, Mucida, Daniel, Lafaille, Juan J

“…Tissue-resident macrophages are the most abundant immune cell population in healthy adipose tissue. Adipose tissue macrophages (ATMs) change during metabolic…”
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High glucose condition increases NADPH oxidase activity in endothelial microparticles that promote vascular inflammation by Jansen, Felix, Yang, Xiaoyan, Franklin, Bernardo S, Hoelscher, Marion, Schmitz, Theresa, Bedorf, Jörg, Nickenig, Georg, Werner, Nikos

“…Diabetes is a major risk factor for cardiovascular diseases. Circulating endothelial microparticles (EMP) are increased in diabetic patients, but their…”
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Tissue adaptation of regulatory and intraepithelial CD4⁺ T cells controls gut inflammation by Sujino, Tomohisa, London, Mariya, van Konijnenburg, David P. Hoytema, Rendon, Tomiko, Buch, Thorsten, Silva, Hernandez M., Lafaille, Juan J., Reis, Bernardo S., Mucida, Daniel

“…Foxp3⁺ regulatory T cells in peripheral tissues (pTregs) are instrumental in limiting inflammatory responses to nonself antigens. Within the intestine, pTregs…”
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