Search Results - "Bernardo, Maria Ester"

How I treat relapsed childhood acute lymphoblastic leukemia by Locatelli, Franco, Schrappe, Martin, Bernardo, Maria Ester, Rutella, Sergio

“…The most common cause of treatment failure in childhood acute lymphoblastic leukemia (ALL) remains relapse, occurring in ∼ 15%-20% of patients. Survival of…”
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Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan by Bernardo, Maria Ester, Piras, Eugenia, Vacca, Adriana, Giorgiani, Giovanna, Zecca, Marco, Bertaina, Alice, Pagliara, Daria, Contoli, Benedetta, Pinto, Rita Maria, Caocci, Giovanni, Mastronuzzi, Angela, La Nasa, Giorgio, Locatelli, Franco

“…Sixty thalassemia patients (median age, 7 years; range, 1-37) underwent allogeneic hematopoietic stem cell transplantation (HSCT) after a preparation combining…”
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Mesenchymal stem/stromal cells: a new ''cells as drugs'' paradigm. Efficacy and critical aspects in cell therapy by de Girolamo, Laura, Lucarelli, Enrico, Alessandri, Giulio, Avanzini, Maria Antonietta, Bernardo, Maria Ester, Biagi, Ettore, Brini, Anna Teresa, D'Amico, Giovanna, Fagioli, Franca, Ferrero, Ivana, Locatelli, Franco, Maccario, Rita, Marazzi, Mario, Parolini, Ornella, Pessina, Augusto, Torre, Maria Luisa, Italian Mesenchymal Stem Cell Group

“…Mesenchymal stem cells (MSCs) were first isolated more than 50 years ago from the bone marrow. Currently MSCs may also be isolated from several alternative…”
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Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation by Bernardo, Maria Ester, Fibbe, Willem E.

“…In addition to their stem/progenitor properties, mesenchymal stromal cells (MSCs) possess broad immunoregulatory properties that are being investigated for…”
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Mesenchymal Stromal Cells: Role in the BM Niche and in the Support of Hematopoietic Stem Cell Transplantation by Crippa, Stefania, Bernardo, Maria Ester

“…Mesenchymal stromal cells (MSCs) are key elements in the bone marrow (BM) niche where they interact with hematopoietic stem progenitor cells (HSPCs) by…”
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An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro‐inflammatory program by Gnani, Daniela, Crippa, Stefania, della Volpe, Lucrezia, Rossella, Valeria, Conti, Anastasia, Lettera, Emanuele, Rivis, Silvia, Ometti, Marco, Fraschini, Gianfranco, Bernardo, Maria Ester, Di Micco, Raffaella

“…Hematopoietic stem and progenitor cells (HSPC) reside in the bone marrow (BM) niche and serve as a reservoir for mature blood cells throughout life. Aging in…”
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The outcome of children with Fanconi anemia given hematopoietic stem cell transplantation and the influence of fludarabine in the conditioning regimen: a report from the Italian pediatric group by Locatelli, Franco, Zecca, Marco, Pession, Andrea, Morreale, Giuseppe, Longoni, Daniela, Di Bartolomeo, Paolo, Porta, Fulvio, Fagioli, Franca, Nobili, Bruno, Bernardo, Maria Ester, Messina, Chiara

“…From Oncoematologia Pediatrica, Fondazione IRCCS Policlinico San Matteo, Università di Pavia, Pavia, Italy (FL, MZ, MEB); Clinica Pediatrica, Università di…”
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Safety and efficacy of mesenchymal stromal cell therapy in autoimmune disorders by Bernardo, Maria Ester, Fibbe, Willem E.

“…Mesenchymal stromal cells (MSCs) are being employed in clinical trials to facilitate engraftment and to treat steroid‐resistant acute graft‐versus‐host disease…”
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Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia by Marktel, Sarah, Scaramuzza, Samantha, Cicalese, Maria Pia, Giglio, Fabio, Galimberti, Stefania, Lidonnici, Maria Rosa, Calbi, Valeria, Assanelli, Andrea, Bernardo, Maria Ester, Rossi, Claudia, Calabria, Andrea, Milani, Raffaella, Gattillo, Salvatore, Benedicenti, Fabrizio, Spinozzi, Giulio, Aprile, Annamaria, Bergami, Alessandra, Casiraghi, Miriam, Consiglieri, Giulia, Masera, Nicoletta, D’Angelo, Emanuela, Mirra, Nadia, Origa, Raffaella, Tartaglione, Immacolata, Perrotta, Silverio, Winter, Robert, Coppola, Milena, Viarengo, Gianluca, Santoleri, Luca, Graziadei, Giovanna, Gabaldo, Michela, Valsecchi, Maria Grazia, Montini, Eugenio, Naldini, Luigi, Cappellini, Maria Domenica, Ciceri, Fabio, Aiuti, Alessandro, Ferrari, Giuliana

“…ß-thalassemia is caused by ß-globin gene mutations resulting in reduced (β + ) or absent (β 0 ) hemoglobin production. Patient life expectancy has recently…”
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Gene therapy for lysosomal storage disorders: recent advances for metachromatic leukodystrophy and mucopolysaccaridosis I by Penati, Rachele, Fumagalli, Francesca, Calbi, Valeria, Bernardo, Maria Ester, Aiuti, Alessandro

“…Lysosomal storage diseases (LSDs) are rare inherited metabolic disorders characterized by a dysfunction in lysosomes, leading to waste material accumulation…”
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Human bone marrow-derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms by ESTER BERNARDO, Maria, ZAFFARONI, Nadia, ZUFFARDI, Orsetta, LOCATELLI, Franco, NOVARA, Francesca, MARIA COMETA, Angela, ANTONIETTA AVANZINI, Maria, MORETTA, Antonia, MONTAGNA, Daniela, MACCARIO, Rita, VILLA, Raffaella, GRAZIA DAIDONE, Maria

“…Significant improvement in the understanding of mesenchymal stem cell (MSC) biology has opened the way to their clinical use. However, concerns regarding the…”
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Ex Vivo and In Vivo Gene Therapy for Mucopolysaccharidoses: State of the Art by Consiglieri, Giulia, Bernardo, Maria Ester, Brunetti-Pierri, Nicola, Aiuti, Alessandro

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Control of immune responses by mesenchymal stromal cells by Fibbe, Willem E, Bernardo, Maria Ester

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Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study by Le Blanc, Katarina, Prof, Frassoni, Francesco, MD, Ball, Lynne, MD, Locatelli, Franco, Prof, Roelofs, Helene, PhD, Lewis, Ian, MD, Lanino, Edoardo, MD, Sundberg, Berit, BSc, Bernardo, Maria Ester, MD, Remberger, Mats, PhD, Dini, Giorgio, MD, Egeler, R Maarten, Prof, Bacigalupo, Andrea, MD, Fibbe, Willem, Prof, Ringdén, Olle, Prof

“…Summary Background Severe graft-versus-host disease (GVHD) is a life-threatening complication after allogeneic transplantation with haemopoietic stem cells…”
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Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity by Pende, Daniela, Marcenaro, Stefania, Falco, Michela, Martini, Stefania, Bernardo, Maria Ester, Montagna, Daniela, Romeo, Elisa, Cognet, Céline, Martinetti, Miryam, Maccario, Rita, Mingari, Maria Cristina, Vivier, Eric, Moretta, Lorenzo, Locatelli, Franco, Moretta, Alessandro

“…We analyzed 21 children with leukemia receiving haploidentical hematopoietic stem cell transplantation (haplo-HSCT) from killer immunoglobulin (Ig)–like…”
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Cotransplantation of ex vivo–expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation by Ball, Lynne M., Bernardo, Maria Ester, Roelofs, Helene, Lankester, Arjan, Cometa, Angela, Egeler, R. Maarten, Locatelli, Franco, Fibbe, Willem E.

“…Haploidentical hematopoietic stem-cell transplantation (HSCT) is associated with an increased risk of graft failure. Adult bone marrow–derived mesenchymal…”
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MPSI Manifestations and Treatment Outcome: Skeletal Focus by De Ponti, Giada, Donsante, Samantha, Frigeni, Marta, Pievani, Alice, Corsi, Alessandro, Bernardo, Maria Ester, Riminucci, Mara, Serafini, Marta

“…Mucopolysaccharidosis type I (MPSI) (OMIM #252800) is an autosomal recessive disorder caused by pathogenic variants in the IDUA gene encoding for the lysosomal…”
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Current and Future Perspective in Hematopoietic Stem Progenitor Cell‐gene Therapy for Inborn Errors of Metabolism by Tucci, Francesca, Consiglieri, Giulia, Cossutta, Matilde, Bernardo, Maria Ester

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Gene therapy for mucopolysaccharidoses: in vivo and ex vivo approaches by Fraldi, Alessandro, Serafini, Marta, Sorrentino, Nicolina Cristina, Gentner, Bernhard, Aiuti, Alessandro, Bernardo, Maria Ester

“…Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders caused by a deficiency in lysosomal enzymes catalyzing the stepwise degradation of…”
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Emapalumab treatment in an ADA-SCID patient with refractory hemophagocytic lymphohistiocytosis-related graft failure and disseminated bacillus Calmette-Guérin infection by Tucci, Francesca, Gallo, Vera, Barzaghi, Federica, Ferrua, Francesca, Migliavacca, Maddalena, Calbi, Valeria, Doglio, Matteo, Fratini, Elena Sophia, Karakas, Zeynep, Guner, Sukru, Zambelli, Matilde, Parisi, Cristina, Milani, Raffaella, Gattillo, Salvatore, Mazzi, Benedetta, Oltolini, Chiara, Barbera, Maurizio, Baldoli, Cristina, Cirillo, Daniela Maria, Asnaghi, Veronica, De Min, Cristina, Cicalese, Maria Pia, Ciceri, Fabio, Aiuti, Alessandro, Bernardo, Maria Ester

“…Emapalumab, a fully human anti-IFNγ monoclonal antibody, has been approved in the US as second-line treatment of primary hemophagocytic lymphohistiocytosis…”
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