Search Results - "Bernardi, Angelina"
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Effects of a tissue-selective estrogen complex on B lymphopoiesis and B cell function
Published in Immunobiology (1979) (01-08-2017)“…Abstract Background/objective 17β-estradiol (E2) has major effects on the immune system. It induces thymic atrophy, inhibits both T and B lymphopoiesis and…”
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Selective estrogen receptor modulators in T cell development and T cell dependent inflammation
Published in Immunobiology (1979) (01-10-2015)“…Abstract Lasofoxifene (las) and bazedoxifene (bza) are third generation selective estrogen receptor modulators (SERMs) with minimal estrogenic side effects,…”
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Selective oestrogen receptor modulators lasofoxifene and bazedoxifene inhibit joint inflammation and osteoporosis in ovariectomised mice with collagen-induced arthritis
Published in Rheumatology (Oxford, England) (01-03-2016)“…RA predominantly affects post-menopausal women and is strongly associated with development of generalised osteoporosis. To find treatments that target both…”
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Phosphorylation site S122 in estrogen receptor α has a tissue‐dependent role in female mice
Published in The FASEB journal (01-12-2020)“…Estrogen treatment increases bone mass and reduces fat mass but is associated with adverse effects in postmenopausal women. Knowledge regarding tissue‐specific…”
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5
Suppression of Experimental Arthritis and Associated Bone Loss by a Tissue-Selective Estrogen Complex
Published in Endocrinology (Philadelphia) (01-03-2016)“…In addition to the systemic inflammation present in rheumatoid arthritis (RA), decreased estradiol levels in postmenopausal RA patients further accelerate bone…”
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The pre-B cell receptor checkpoint
Published in FEBS letters (18-06-2010)“…B lymphocytes are essential antibody-producing cells of the immune system. During the development of progenitor B cells to mature B cells that express a…”
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Roles of activating functions 1 and 2 of estrogen receptor α in lymphopoiesis
Published in Journal of endocrinology (01-02-2018)“…Apart from the role of sex steroids in reproduction, sex steroids are also important regulators of the immune system. 17β-estradiol (E2) represses T and B cell…”
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Absence of surrogate light chain results in spontaneous autoreactive germinal centres expanding VH81X-expressing B cells
Published in Nature communications (11-05-2015)“…Random recombination of antibody heavy- and light-chain genes results in a diverse B-cell receptor (BCR) repertoire including self-reactive BCRs. However,…”
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α7 Nicotinic Acetylcholine Receptor Is Expressed in Human Atherosclerosis and Inhibits Disease in Mice—Brief Report
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2014)“…OBJECTIVE—Cholinergic pathways of the autonomic nervous system are known to modulate inflammation. Because atherosclerosis is a chronic inflammatory condition,…”
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10
Surrogate light chain is required for central and peripheral B‐cell tolerance and inhibits anti‐DNA antibody production by marginal zone B cells
Published in European journal of immunology (01-04-2015)“…Selection of the primary antibody repertoire takes place in pro‐/pre‐B cells, and subsequently in immature and transitional B cells. At the first checkpoint, μ…”
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11
Absence of surrogate light chain results in spontaneous autoreactive germinal centres expanding V(H)81X-expressing B cells
Published in Nature communications (11-05-2015)“…Random recombination of antibody heavy- and light-chain genes results in a diverse B-cell receptor (BCR) repertoire including self-reactive BCRs. However,…”
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12
Nutritional impact on Immunological maturation during Childhood in relation to the Environment (NICE): a prospective birth cohort in northern Sweden
Published in BMJ open (2018)“…IntroductionPrenatal and neonatal environmental factors, such as nutrition, microbes and toxicants, may affect health throughout life. Many diseases, such as…”
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13
Effects of lasofoxifene and bazedoxifene on B cell development and function
Published in Immunity, Inflammation and Disease (01-12-2014)“…The third generation selective estrogen receptor modulators lasofoxifene (las) and bazedoxifene (bza) are indicated for treatment of postmenopausal…”
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14
alpha 7 Nicotinic Acetylcholine Receptor Is Expressed in Human Atherosclerosis and Inhibits Disease in Mice-Brief Report
Published in Arteriosclerosis, thrombosis, and vascular biology (2014)“…Objective-Cholinergic pathways of the autonomic nervous system are known to modulate inflammation. Because atherosclerosis is a chronic inflammatory condition,…”
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Journal Article -
15
SUN-744 Phosphorylation Site S122 in Estrogen Receptor α Has a Tissue-Dependent Role in Female Mice
Published in Journal of the Endocrine Society (08-05-2020)“…Abstract Estrogen treatment increases bone mass and reduces fat mass but is associated with adverse effects in postmenopausal women. Knowledge regarding…”
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