Search Results - "Bernard DUTRILLAUX"

Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide by Brison, Olivier, El-Hilali, Sami, Azar, Dana, Koundrioukoff, Stéphane, Schmidt, Mélanie, Nähse, Viola, Jaszczyszyn, Yan, Lachages, Anne-Marie, Dutrillaux, Bernard, Thermes, Claude, Debatisse, Michelle, Chen, Chun-Long

“…Common fragile sites (CFSs) are chromosome regions prone to breakage upon replication stress known to drive chromosome rearrangements during oncogenesis. Most…”
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Common Fragile Site Profiling in Epithelial and Erythroid Cells Reveals that Most Recurrent Cancer Deletions Lie in Fragile Sites Hosting Large Genes by Le Tallec, Benoît, Millot, Gaël Armel, Blin, Marion Esther, Brison, Olivier, Dutrillaux, Bernard, Debatisse, Michelle

“…Cancer genomes exhibit numerous deletions, some of which inactivate tumor suppressor genes and/or correspond to unstable genomic regions, notably common…”
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Molecular profiling of common fragile sites in human fibroblasts by Le Tallec, Benoî, Dutrillaux, Bernard, Lachages, Anne-Marie, Millot, Gael Armel, Brison, Olivier, Debatisse, Michelle

“…Common fragile sites (CFSs) can drive genomic instability. The basis for their fragile nature is not clear, but lymphocyte CFSs have been mapped to regions…”
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Loss of Y chromosome may be a synapomorphy of the tribe Lepturini (Coleoptera: Cerambycidae: Lepturinae) by DUTRILLAUX, Anne-Marie, DUTRILLAUX, Bernard

“…Phylogeny and higher classification of the cerambycid subfamily Lepturinae remain controversial. Here we report the results of a cytogenetic study of 18…”
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Different behaviour of C-banded peri-centromeric heterochromatin between sex chromosomes and autosomes in Polyphagan beetles by Dutrillaux, Anne-Marie, Dutrillaux, Bernard

“…Heterochromatin variation was studied after C-banding of male karyotypes with a XY sex formula from 224 species belonging to most of the main families of…”
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Telomeric heterochromatin and meiotic recombination in three species of Coleoptera (Dorcadion olympicum Ganglebauer, Stephanorrhina princeps Oberthür and Macraspis tristis Laporte) by Dutrillaux, Anne-Marie, Dutrillaux, Bernard

“…Centromeres are generally embedded in heterochromatin, which is assumed to have a negative impact on meiotic recombination in adjacent regions, a condition…”
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Establishment of human colon cancer cell lines from fresh tumors versus xenografts : Comparison of success rate and cell line features by DANGLES-MARIE, Virginie, POCARD, Marc, DUTRILLAUX, Bernard, PRAZ, Francoise, BELLET, Dominique, POUPON, Marie-France, RICHON, Sophie, WEISWALD, Louis-Bastien, ASSAYAG, Franck, SAULNIER, Patrick, JUDDE, Jean-Gabriel, JANNEAU, Jean-Louis, AUGER, Nathalie, VALIDIRE, Pierre

“…Obtaining representative human colon cancer cell lines from fresh tumors is technically difficult. Using 32 tumor fragments from patients with colon cancer,…”
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Premature Condensation Induces Breaks at the Interface of Early and Late Replicating Chromosome Bands Bearing Common Fragile Sites by Eliane El Achkar, Michelle Gerbault-Seureau, Martine Muleris, Dutrillaux, Bernard, Debatisse, Michelle

“…Various studies suggest a tight relationship between chromosome rearrangements driving tumor progression and breaks at loci called common fragile sites. Most…”
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Side Population' cells in adult mouse testis express Bcrp1 gene and are enriched in spermatogonia and germinal stem cells by Lassalle, Bruno, Bastos, Henri, Louis, Jean Paul, Riou, Lydia, Testart, Jacques, Dutrillaux, Bernard, Fouchet, Pierre, Allemand, Isabelle

“…Stem cells in various somatic tissues (bone marrow, skeletal muscle) can be identified by the `Side Population' marker based on Hoechst 33342 efflux. We show…”
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Unbalanced sex ratio and triploidy in the genus Cyclocephala (Coleoptera: Scarabaeoidea: Dynastidae) in the Lesser Antilles: An example of parthenogenesis on islands? by Bernard DUTRILLAUX, Dominique PLUOT-SIGWALT, Anne-Marie DUTRILLAUX

“…Sex ratio and chromosomes studies were performed on six of the seven species of genus Cyclocephala present in the Lesser Antilles. Most sex ratios based on…”
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Molecular Structure of Double-Minute Chromosomes Bearing Amplified Copies of the Epidermal Growth Factor Receptor Gene in Gliomas by Vogt, Nicolas, Lefèvre, Sandrine-Hélène, Apiou, Françoise, Dutrillaux, Anne-Marie, Cör, Andrej, Leuraud, Pascal, Poupon, Marie-France, Dutrillaux, Bernard, Debatisse, Michelle, Malfoy, Bernard, Alt, Frederick W.

“…Amplification of the epidermal growth factor receptor gene on double minutes is recurrently observed in cells of advanced gliomas, but the structure of these…”
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(Ovo-)viviparity in the darkling beetle, Alegoria castelnaui (Tenebrioninae: Ulomini), from Guadeloupe by Anne Marie DUTRILLAUX, Dominique PLUOT-SIGWALT, Bernard DUTRILLAUX

“…In the course of cytogenetic studies on Alegoria castelnaui Fleutiaux & Sallé 1889 (Coleoptera: Tenebrionidae: Tenebrioninae: Ulomini) from Guadeloupe, a…”
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Requirement of Poly (ADP-Ribose) Polymerase in Recovery from DNA Damage in Mice and in Cells by De Murcia, Josiane Menissier, Niedergang, Claude, Trucco, Carlotta, Ricoul, Michele, Dutrillaux, Bernard, Mark, Manuel, Oliver, F. Javier, Masson, Murielle, Dierich, Andree, LeMeur, Marianne, Walztinger, Caroline, Chambon, Pierre, De Murcia, Gilbert

“…Poly(ADP-ribose) polymerase [PARP; NAD+ADP-ribosyltransferase; NAD+; poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyltransferase, EC 2.4.2.30] is a…”
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Genetic alterations associated with acquired temozolomide resistance in SNB-19, a human glioma cell line by Auger, Nathalie, Thillet, Joëlle, Wanherdrick, Krystell, Idbaih, Ahmed, Legrier, Marie-Emmanuelle, Dutrillaux, Bernard, Sanson, Marc, Poupon, Marie-France

“…Gliomas are highly lethal neoplasms that cannot be cured by currently available therapies. Temozolomide is a recently introduced alkylating agent that has…”
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NSD3, a New SET Domain-Containing Gene, Maps to 8p12 and Is Amplified in Human Breast Cancer Cell Lines by Angrand, Pierre-Olivier, Apiou, Françoise, Stewart, A.Francis, Dutrillaux, Bernard, Losson, Régine, Chambon, Pierre

“…We describe the isolation and characterization of NSD3, the third member of a gene family including Nsd1 and NSD2. Murine Nsd1 was isolated in a search for…”
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Common Fragile Sites Nested at the Interfaces of Early and Late-Replicating Chromosome Bands : Cis Acting Components of the G2/M Checkpoint? by Debatisse, MIchelle, Achkar, Eliane El, Dutrillaux, Bernard

“…Common fragile sites (CFS) are evolutionary conserved loci where damage appears recurrently upon treatments perturbing DNA synthesis. Although long studied,…”
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Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours by CHEVILLARD, S, RADICELLA, J. P, LEVALOIS, C, LEBEAU, J, POUPON, M.-F, OUDARD, S, DUTRILLAUX, B, BOITEUX, S

“…The human OGG1 gene encodes a DNA glycosylase activity catalysing the excision of the mutagenic lesion 7,8-dihydro-8-oxoguanine from oxidatively damaged DNA…”
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Chromosomal instability in near-diploid colorectal cancer: a link between numbers and structure by Muleris, Martine, Chalastanis, Alexandra, Meyer, Nicolas, Lae, Marick, Dutrillaux, Bernard, Sastre-Garau, Xavier, Hamelin, Richard, Fléjou, Jean-Francois, Duval, Alex

“…Chromosomal instability (CIN) plays a crucial role in tumor development and occurs mainly as the consequence of either missegregation of normal chromosomes…”
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Characterization of a new cytogenetic subtype of ductal breast carcinomas by MOLIST, Romain, REMVIKOS, Yorghos, DUTRILLAUX, Bernard, MULERIS, Martine

“…About 50% of ductal breast carcinomas do not yield analysable karyotypes after short-term culturing. Comparison of the cytogenetic subset to the whole data set…”
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Origin of the complex karyotype of the polyploid parthenogenetic grasshopper Saga pedo (Orthoptera: Tettigoniidae) by Anne Marie DUTRILLAUX, Michèle LEMONNIER-DARCEMONT, Christian DARCEMONT, Vladimir KRPAČ, Pierre FOUCHET, Bernard DUTRILLAUX

“…Karyotypes of the polyploid parthenogenetic species Saga pedo from four localities in France and the Republic of Macedonia were constructed and compared. All…”
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