Search Results - "Bernard, Moussian"
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Structural basis for diamide modulation of ryanodine receptor
Published in Nature chemical biology (01-11-2020)“…The diamide insecticide class is one of the top-selling insecticides globally. They are used to control a wide range of pests by targeting their ryanodine…”
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2
The apical plasma membrane of chitin-synthesizing epithelia
Published in Insect science (01-04-2013)“…Chitin is the second most abundant polysaccharide on earth. It is produced at the apical side of epidermal, tracheal, fore-, and hindgut epithelial cells in…”
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3
The role of GlcNAc in formation and function of extracellular matrices
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01-02-2008)“…N-acetylglucosamine (GlcNAc) is an abundant hexose that as a monomer or as part of macromolecules plays multiple roles in eukaryotic cells. Especially as a…”
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Double cuticle barrier in two global pests, the whitefly Trialeurodes vaporariorum and the bedbug Cimex lectularius
Published in Journal of experimental biology (15-04-2017)“…The integument protects the organism against penetration of xenobiotics and water that would potentially interfere with homeostasis. In insects that play key…”
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A comprehensive omics analysis and functional survey of cuticular proteins in the brown planthopper
Published in Proceedings of the National Academy of Sciences - PNAS (15-05-2018)“…Cuticle, mainly composed of chitin and cuticular proteins (CPs), is a multifunctional structure of arthropods. CPs usually account for >1% of the total insect…”
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Drosophila, Chitin and Insect Pest Management
Published in Current pharmaceutical design (01-01-2020)“…Insects are a great menace in agriculture and vectors of human diseases. Hence, controlling insect populations is an important issue worldwide. A common…”
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Nuclear receptor HR3 controls locust molt by regulating chitin synthesis and degradation genes of Locusta migratoria
Published in Insect biochemistry and molecular biology (01-01-2018)“…During growth and development of insects, the steroid hormone 20-Hydroxyecdysone (20E) regulates the molting process through activation of a series of genes…”
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Helicoidal Organization of Chitin in the Cuticle of the Migratory Locust Requires the Function of the Chitin Deacetylase2 Enzyme (LmCDA2)
Published in The Journal of biological chemistry (18-11-2016)“…In the three-dimensional extracellular matrix of the insect cuticle, horizontally aligned microfibrils composed of the polysaccharide chitin and associated…”
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The putative chitin deacetylases Serpentine and Vermiform have non-redundant functions during Drosophila wing development
Published in Insect biochemistry and molecular biology (01-07-2019)“…The chitin modifying deacetylases (CDA) CDA1 and CDA2 have been reported to play partially redundant roles during insect cuticle formation and molting and…”
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Three-dimensional reconstruction of a whole insect reveals its phloem sap-sucking mechanism at nano-resolution
Published in eLife (23-02-2021)“…Using serial block-face scanning electron microscopy, we report on the internal 3D structures of the brown planthopper, (Hemiptera: Delphacidae) at nanometer…”
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Dorsoventral Axis Formation in the Drosophila Embryo—Shaping and Transducing a Morphogen Gradient
Published in Current biology (08-11-2005)“…The graded nuclear location of the transcription factor Dorsal along the dorsoventral axis of the early Drosophila embryo provides positional information for…”
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LmCYP4G102: An oenocyte-specific cytochrome P450 gene required for cuticular waterproofing in the migratory locust, Locusta migratoria
Published in Scientific reports (22-07-2016)“…Cytochrome P450 superfamily proteins play important roles in detoxification of xenobiotics and during physiological and developmental processes. To contribute…”
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The wing-specific cuticular protein LmACP7 is essential for normal wing morphogenesis in the migratory locust
Published in Insect biochemistry and molecular biology (01-09-2019)“…Wings are an indispensable structure in many insects for their foraging, courtship, escape from predators, and migration. Cuticular proteins are major…”
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Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing
Published in Nature communications (07-10-2016)“…The TOR and Insulin/IGF signalling (IIS) network controls growth, metabolism and ageing. Although reducing TOR or insulin signalling can be beneficial for…”
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15
Boudin trafficking reveals the dynamic internalisation of specific septate junction components in Drosophila
Published in PloS one (2017)“…The maintenance of paracellular barriers in invertebrate epithelia depends on the integrity of specific cell adhesion structures known as septate junctions…”
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Molecular understanding of the translational models and the therapeutic potential natural products of Parkinson's disease
Published in Biomedicine & pharmacotherapy (01-11-2022)“…Parkinson's disease is the second most prevalent neurodegenerative disease after Alzheimer's disease, mostly happened in the elder population and the…”
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Epidermal Cell Surface Structure and Chitin-Protein Co-assembly Determine Fiber Architecture in the Locust Cuticle
Published in ACS applied materials & interfaces (10-06-2020)“…The geometrical similarity of helicoidal fiber arrangement in many biological fibrous extracellular matrices, such as bone, plant cell wall, or arthropod…”
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A feedback mechanism converts individual cell features into a supracellular ECM structure in Drosophila trachea
Published in eLife (02-02-2016)“…The extracellular matrix (ECM), a structure contributed to and commonly shared by many cells in an organism, plays an active role during morphogenesis. Here,…”
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Dysfunction of Oskyddad causes Harlequin-type ichthyosis-like defects in Drosophila melanogaster
Published in PLoS genetics (13-01-2020)“…Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an extracellular coat, the cuticle, that plays a major role in…”
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Extra-corporeal detoxification in insects
Published in Heliyon (15-04-2024)“…Upon uptake of toxins, insects launch a detoxification program. This program is deployed in multiple organs and cells to raise their tolerance against the…”
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