Search Results - "Bernados, David"

PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8 + T-cell Function by Whelan, Sarah, Ophir, Eran, Kotturi, Maya F, Levy, Ofer, Ganguly, Sudipto, Leung, Ling, Vaknin, Ilan, Kumar, Sandeep, Dassa, Liat, Hansen, Kyle, Bernados, David, Murter, Benjamin, Soni, Abha, Taube, Janis M, Fader, Amanda Nickles, Wang, Tian-Li, Shih, Ie-Ming, White, Mark, Pardoll, Drew M, Liang, Spencer C

“…Although checkpoint inhibitors that block CTLA-4 and PD-1 have improved cancer immunotherapies, targeting additional checkpoint receptors may be required to…”
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Novel CD123xCD3 Bispecific Igm Antibody, Igm-2537, Potently Induces T-Cell Mediated Cytotoxicity of Acute Myeloid Leukemia Cells In Vivo and in Vitro with Minimal Cytokine Release by Li, Gene, Ye, Zhongde, Yakkundi, Poonam, Manlusoc, Marigold, Logronio, Kathryn, Tahrani, Leyla, Rosete, Rodnie, Bernados, David, Hinton, Paul, Pandya, Deepal, Hanna, Nardeen, Anantam, Jey, Kotturi, Maya F, Bogaert, Liz, Hong, Jiyoung, Tsai, Christina, Manley, Thomas, Keyt, Bruce A, Sinclair, Angus M., Liu, Liqin

“…Introduction: New therapeutics are needed for the effective treatment of acute myeloid leukemia (AML), as standard chemotherapeutics are poorly tolerated and…”
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COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade by Hansen, Kyle, Kumar, Sandeep, Logronio, Kathryn, Whelan, Sarah, Qurashi, Samir, Cheng, Hsin-Yuan, Drake, Andrew, Tang, Margaret, Wall, Patrick, Bernados, David, Leung, Ling, Ophir, Eran, Alteber, Zoya, Cojocaru, Gady, Galperin, Moran, Frenkel, Masha, White, Mark, Hunter, John, Liang, Spencer C., Kotturi, Maya F.

“…Immune checkpoint inhibitors (ICIs) have emerged as promising therapies for the treatment of cancer. However, existing ICIs, namely PD-(L)1 and CTLA-4…”
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