Search Results - "Bermudez Humaran, Luis"

Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria by LeBlanc, Jean Guy, Chain, Florian, Martín, Rebeca, Bermúdez-Humarán, Luis G, Courau, Stéphanie, Langella, Philippe

“…The aim of this review is to summarize the effect in host energy metabolism of the production of B group vitamins and short chain fatty acids (SCFA) by…”
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Faecalibacterium: a bacterial genus with promising human health applications by Martín, Rebeca, Rios-Covian, David, Huillet, Eugénie, Auger, Sandrine, Khazaal, Sarah, Bermúdez-Humarán, Luis G, Sokol, Harry, Chatel, Jean-Marc, Langella, Philippe

“…Abstract In humans, many diseases are associated with alterations in gut microbiota, namely increases or decreases in the abundance of specific bacterial…”
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Role of commensal and probiotic bacteria in human health: a focus on inflammatory bowel disease by Martín, Rebeca, Miquel, Sylvie, Ulmer, Jonathan, Kechaou, Noura, Langella, Philippe, Bermúdez-Humarán, Luis G

“…The human gut is one of the most complex ecosystems, composed of 1013-1014 microorganisms which play an important role in human health. In addition, some food…”
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Lactococci and lactobacilli as mucosal delivery vectors for therapeutic proteins and DNA vaccines by Bermúdez-Humarán, Luis G, Kharrat, Pascale, Chatel, Jean-Marc, Langella, Philippe

“…Food-grade Lactic Acid Bacteria (LAB) have been safely consumed for centuries by humans in fermented foods. Thus, they are good candidates to develop novel…”
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Probiotic Strain Lactobacillus casei BL23 Prevents Colitis-Associated Colorectal Cancer by Jacouton, Elsa, Chain, Florian, Sokol, Harry, Langella, Philippe, Bermúdez-Humarán, Luis G

“…The gut microbiota plays a major role in intestinal health, and an imbalance in its composition can lead to chronic gut inflammation and a predisposition to…”
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Engineering lactococci and lactobacilli for human health by Bermúdez-Humarán, Luis G, Aubry, Camille, Motta, Jean-Paul, Deraison, Celine, Steidler, Lothar, Vergnolle, Nathalie, Chatel, Jean-Marc, Langella, Philippe

“…Highlights • Recombinant lactococci and lactobacilli have been successfully used in the last years as safe mucosal delivery vectors for molecules of health…”
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Modulation of the PI3K/Akt/mTOR signaling pathway by probiotics as a fruitful target for orchestrating the immune response by Mohseni, Amir Hossein, Casolaro, Vincenzo, Bermúdez-Humarán, Luis G., Keyvani, Hossein, Taghinezhad-S, Sedigheh

“…The mammalian target of rapamycin (mTOR) and the phosphatidylinositol-3-kinase (PI3K)/protein kinase B or Akt (PKB/Akt) signaling pathways are considered as…”
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Drying process strongly affects probiotics viability and functionalities by Iaconelli, Cyril, Lemetais, Guillaume, Kechaou, Noura, Chain, Florian, Bermúdez-Humarán, Luis G., Langella, Philippe, Gervais, Patrick, Beney, Laurent

“…•4 viability and 3 functionality bacterial markers measured after 3 drying processes.•Cell functionality is not directly linked to cell survival.•Drying…”
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Twenty years of research on HPV vaccines based on genetically modified lactic acid bacteria: an overview on the gut-vagina axis by Taghinezhad-S, Sedigheh, Keyvani, Hossein, Bermúdez-Humarán, Luis G., Donders, Gilbert G. G., Fu, Xiangsheng, Mohseni, Amir Hossein

“…Most cervical cancer (CxCa) are related to persistent infection with high-risk human papillomavirus (HR-HPV) in the cervical mucosa, suggesting that an…”
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From Probiotics to Psychobiotics: Live Beneficial Bacteria Which Act on the Brain-Gut Axis by Bermúdez-Humarán, Luis G, Salinas, Eva, Ortiz, Genaro G, Ramirez-Jirano, Luis J, Morales, J Alejandro, Bitzer-Quintero, Oscar K

“…There is an important relationship between probiotics, psychobiotics and cognitive and behavioral processes, which include neurological, metabolic, hormonal…”
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Searching for the Bacterial Effector: The Example of the Multi-Skilled Commensal Bacterium Faecalibacterium prausnitzii by Martín, Rebeca, Bermúdez-Humarán, Luis G, Langella, Philippe

“…represents approximately 5% of the total fecal microbiota in healthy adults being one of the most abundant bacterium in the human intestinal microbiota of…”
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Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients by Sokol, Harry, Pigneur, Bénédicte, Watterlot, Laurie, Lakhdari, Omar, Bermúdez-Humarán, Luis G, Gratadoux, Jean-Jacques, Blugeon, Sébastien, Bridonneau, Chantal, Furet, Jean-Pierre, Corthier, Gérard, Grangette, Corinne, Vasquez, Nadia, Pochart, Philippe, Trugnan, Germain, Thomas, Ginette, Blottière, Hervé M, Doré, Joël, Marteau, Philippe, Seksik, Philippe, Langella, Philippe

“…A decrease in the abundance and biodiversity of intestinal bacteria within the dominant phylum Firmicutes has been observed repeatedly in Crohn disease (CD)…”
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Lactobacillus casei BL23 regulates Treg and Th17 T-cell populations and reduces DMH-associated colorectal cancer by Lenoir, Marion, Del Carmen, Silvina, Cortes-Perez, Naima G, Lozano-Ojalvo, Daniel, Muñoz-Provencio, Diego, Chain, Florian, Langella, Philippe, de Moreno de LeBlanc, Alejandra, LeBlanc, Jean Guy, Bermúdez-Humarán, Luis G

“…Chronic intestinal inflammation alters host physiology and could lead to colorectal cancer (CRC). We have previously reported beneficial effects of the…”
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The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models by Martín, Rebeca, Chain, Florian, Miquel, Sylvie, Lu, Jun, Gratadoux, Jean-Jacques, Sokol, Harry, Verdu, Elena F, Bercik, Premysl, Bermúdez-Humarán, Luis G, Langella, Philippe

“…The abundance of Faecalibacterium prausnitzii, an abundant and representative bacterium of Firmicutes phylum, has consistently been observed to be lower in…”
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Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases by Michaudel, Chloé, Danne, Camille, Agus, Allison, Magniez, Aurélie, Aucouturier, Anne, Spatz, Madeleine, Lefevre, Antoine, Kirchgesner, Julien, Rolhion, Nathalie, Wang, Yazhou, Lavelle, Aonghus, Galbert, Chloé, Da Costa, Gregory, Poirier, Maxime, Lapière, Alexia, Planchais, Julien, Nádvorník, Petr, Illes, Peter, Oeuvray, Cyriane, Creusot, Laura, Michel, Marie-Laure, Benech, Nicolas, Bourrier, Anne, Nion-Larmurier, Isabelle, Landman, Cecilia, Richard, Mathias L, Emond, Patrick, Seksik, Philippe, Beaugerie, Laurent, Arguello, Rafael Rose, Moulin, David, Mani, Sridhar, Dvorák, Zdenek, Bermúdez-Humarán, Luis G, Langella, Philippe, Sokol, Harry

“…The extent to which tryptophan (Trp) metabolism alterations explain or influence the outcome of inflammatory bowel diseases (IBDs) is still unclear. However,…”
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Mucosal targeting of therapeutic molecules using genetically modified lactic acid bacteria: an update by LeBlanc, Jean Guy, Aubry, Camille, Cortes-Perez, Naima G., de Moreno de LeBlanc, Alejandra, Vergnolle, Nathalie, Langella, Philippe, Azevedo, Vasco, Chatel, Jean-Marc, Miyoshi, Anderson, Bermúdez-Humarán, Luis G.

“…Abstract Lactic acid bacteria (LAB) represent a heterogeneous group of microorganisms naturally present in many foods and those have proved to be effective…”
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Serine protease inhibitors protect better than IL-10 and TGF-β anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci by Bermúdez-Humarán, Luis G, Motta, Jean-Paul, Aubry, Camille, Kharrat, Pascale, Rous-Martin, Laurence, Sallenave, Jean-Michel, Deraison, Céline, Vergnolle, Nathalie, Langella, Philippe

“…Different studies have described the successful use of recombinant lactic acid bacteria (recLAB) to deliver anti-inflammatory molecules at the mucosal level to…”
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Identification of novel anti-inflammatory probiotic strains isolated from pulque by Torres-Maravilla, Edgar, Lenoir, Marion, Mayorga-Reyes, Lino, Allain, Thibault, Sokol, Harry, Langella, Philippe, Sánchez-Pardo, María E, Bermúdez-Humarán, Luis G

“…Probiotics are live microorganisms which when administered in adequate amounts, confer health benefits on the host. Their use is more and more widespread for…”
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Use of superoxide dismutase and catalase producing lactic acid bacteria in TNBS induced Crohn's disease in mice by LeBlanc, Jean Guy, del Carmen, Silvina, Miyoshi, Anderson, Azevedo, Vasco, Sesma, Fernando, Langella, Philippe, Bermúdez-Humarán, Luis G., Watterlot, Laurie, Perdigon, Gabriela, de Moreno de LeBlanc, Alejandra

“…Reactive oxygen species are involved in various aspects of intestinal inflammation and tumor development. Decreasing their levels using antioxidant enzymes,…”
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Live bacterial biotherapeutics in the clinic by Bermúdez-Humarán, Luis G, Langella, Philippe

“…An engineered probiotic designed to treat a metabolic disease enters clinical trials…”
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