Search Results - "Berman, Judith"

Ploidy plasticity: a rapid and reversible strategy for adaptation to stress by Berman, Judith

“…Organisms must be able to grow in a broad range of conditions found in their normal growth environment and for a species to survive, at least some cells in a…”
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Tackling the emerging threat of antifungal resistance to human health by Fisher, Matthew C., Alastruey-Izquierdo, Ana, Berman, Judith, Bicanic, Tihana, Bignell, Elaine M., Bowyer, Paul, Bromley, Michael, Brüggemann, Roger, Garber, Gary, Cornely, Oliver A., Gurr, Sarah. J., Harrison, Thomas S., Kuijper, Ed, Rhodes, Johanna, Sheppard, Donald C., Warris, Adilia, White, P. Lewis, Xu, Jianping, Zwaan, Bas, Verweij, Paul E.

“…Invasive fungal infections pose an important threat to public health and are an under-recognized component of antimicrobial resistance, an emerging crisis…”
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The importance of antimicrobial resistance in medical mycology by Gow, Neil A. R., Johnson, Carolyn, Berman, Judith, Coste, Alix T., Cuomo, Christina A., Perlin, David S., Bicanic, Tihana, Harrison, Thomas S., Wiederhold, Nathan, Bromley, Mike, Chiller, Tom, Edgar, Keegan

“…Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global health care priority. Some analyses, including the O’Neill report, have…”
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Multidrug-Resistant Candida haemulonii and C. auris, Tel Aviv, Israel by Ben-Ami, Ronen, Berman, Judith, Novikov, Ana, Bash, Edna, Shachor-Meyouhas, Yael, Zakin, Shiri, Maor, Yasmin, Tarabia, Jalal, Schechner, Vered, Adler, Amos, Finn, Talya

“…Candida auris and C. haemulonii are closely related, multidrug-resistant emerging fungal pathogens that are not readily distinguishable with phenotypic assays…”
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Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia by Rosenberg, Alexander, Ene, Iuliana V., Bibi, Maayan, Zakin, Shiri, Segal, Ella Shtifman, Ziv, Naomi, Dahan, Alon M., Colombo, Arnaldo Lopes, Bennett, Richard J., Berman, Judith

“…Tolerance to antifungal drug concentrations above the minimal inhibitory concentration (MIC) is rarely quantified, and current clinical recommendations suggest…”
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Genomic Plasticity of the Human Fungal Pathogen Candida albicans by Selmecki, Anna, Forche, Anja, Berman, Judith

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Regulation of heme utilization and homeostasis in Candida albicans by Andrawes, Natalie, Weissman, Ziva, Pinsky, Mariel, Moshe, Shilat, Berman, Judith, Kornitzer, Daniel

“…Heme (iron-protoporphyrin IX) is an essential but potentially toxic cellular cofactor. While most organisms are heme prototrophs, many microorganisms can…”
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A positive postdoctoral experience is related to quality supervision and career mentoring, collaborations, networking and a nurturing research environment by Scaffidi, Amelia K, Berman, Judith E

“…For postdocs to have the best chances of achieving their career goals they need to not only acquire discipline-specific research experience, but also…”
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The distinct morphogenic states of Candida albicans by Sudbery, Peter, Gow, Neil, Berman, Judith

“…The human fungal pathogen, Candida albicans can grow in at least three different morphologies: yeast, pseudohyphae and hyphae. Further morphological forms…”
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isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1 by Selmecki, Anna, Gerami-Nejad, Maryam, Paulson, Carsten, Forche, Anja, Berman, Judith

“…Acquired azole resistance is a serious clinical problem that is often associated with the appearance of aneuploidy and, in particular, with the formation of an…”
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The ‘obligate diploid’ Candida albicans forms mating-competent haploids by Hickman, Meleah A., Zeng, Guisheng, Forche, Anja, Hirakawa, Matthew P., Abbey, Darren, Harrison, Benjamin D., Wang, Yan-Ming, Su, Ching-hua, Bennett, Richard J., Wang, Yue, Berman, Judith

“…Candida albicans , the most prevalent human fungal pathogen, is considered to be an obligate diploid that carries recessive lethal mutations throughout the…”
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A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole by Harrison, Benjamin D, Hashemi, Jordan, Bibi, Maayan, Pulver, Rebecca, Bavli, Danny, Nahmias, Yaakov, Wellington, Melanie, Sapiro, Guillermo, Berman, Judith

“…Candida albicans, the most prevalent human fungal pathogen, is generally diploid. However, 50% of isolates that are resistant to fluconazole (FLC), the most…”
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The evolution of drug resistance in clinical isolates of Candida albicans by Ford, Christopher B, Funt, Jason M, Abbey, Darren, Issi, Luca, Guiducci, Candace, Martinez, Diego A, Delorey, Toni, Li, Bi Yu, White, Theodore C, Cuomo, Christina, Rao, Reeta P, Berman, Judith, Thompson, Dawn A, Regev, Aviv

“…Candida albicans is both a member of the healthy human microbiome and a major pathogen in immunocompromised individuals. Infections are typically treated with…”
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Polyploid titan cells produce haploid and aneuploid progeny to promote stress adaptation by Gerstein, Aleeza C, Fu, Man Shun, Mukaremera, Liliane, Li, Zhongming, Ormerod, Kate L, Fraser, James A, Berman, Judith, Nielsen, Kirsten

“…Cryptococcus neoformans is a major life-threatening fungal pathogen. In response to the stress of the host environment, C. neoformans produces large polyploid…”
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Chromatin Profiling of the Repetitive and Nonrepetitive Genomes of the Human Fungal Pathogen Candida albicans by Price, Robert Jordan, Weindling, Esther, Berman, Judith, Buscaino, Alessia

“…Eukaryotic genomes are packaged into chromatin structures that play pivotal roles in regulating all DNA-associated processes. Histone posttranslational…”
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Flexibility of centromere and kinetochore structures by Burrack, Laura S, Berman, Judith

“…Centromeres, and the kinetochores that assemble on them, are essential for accurate chromosome segregation. Diverse centromere organization patterns and…”
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Targeting the Adaptability of Heterogeneous Aneuploids by Chen, Guangbo, Mulla, Wahid A., Kucharavy, Andrei, Tsai, Hung-Ji, Rubinstein, Boris, Conkright, Juliana, McCroskey, Scott, Bradford, William D., Weems, Lauren, Haug, Jeff S., Seidel, Chris W., Berman, Judith, Li, Rong

“…Aneuploid genomes, characterized by unbalanced chromosome stoichiometry (karyotype), are associated with cancer malignancy and drug resistance of pathogenic…”
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Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance by Selmecki, Anna M, Dulmage, Keely, Cowen, Leah E, Anderson, James B, Berman, Judith

“…The evolution of drug resistance is an important process that affects clinical outcomes. Resistance to fluconazole, the most widely used antifungal, is often…”
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Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes by Yang, Feng, Scopel, Eduardo F C, Li, Hao, Sun, Liu-Liu, Kawar, Nora, Cao, Yong-Bing, Jiang, Yuan-Ying, Berman, Judith

“…Antifungal drug tolerance is a response distinct from resistance, in which cells grow slowly above the MIC. Here, we found that the majority (69.2%) of 133…”
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Tunicamycin Potentiates Antifungal Drug Tolerance via Aneuploidy in Candida albicans by Yang, Feng, Gritsenko, Vladimir, Slor Futterman, Yaniv, Gao, Lu, Zhen, Cheng, Lu, Hui, Jiang, Yuan-Ying, Berman, Judith

“…How cells exposed to one stress are later able to better survive other types of stress is not well understood. In eukaryotic organisms, physiological and…”
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